Issue 32, 2020

Finely tuned Prussian blue-based nanoparticles and their application in disease treatment

Abstract

The Prussian blue (PB) based nanostructure is a mixed-valence coordination network with excellent biosafety, remarkable photothermal effect and multiple enzyme-mimicking behaviours. Compared with other nanomaterials, PB-based nanoparticles (NPs) exhibit several unparalleled advantages in biomedical applications. This review begins with the chemical composition and physicochemical properties of PB-based NPs. The tuning strategies of PB-based NPs and their biomedical properties are systemically demonstrated. Afterwards, the biomedical applications of PB-based NPs are comprehensively recounted, mainly focusing on treatment of tumors, bacterial infection and inflammatory diseases. Finally, the challenges and future prospects of PB-based NPs and their application in disease treatment are discussed.

Graphical abstract: Finely tuned Prussian blue-based nanoparticles and their application in disease treatment

Article information

Article type
Review Article
Submitted
15 may. 2020
Accepted
23 jun. 2020
First published
10 jul. 2020

J. Mater. Chem. B, 2020,8, 7121-7134

Finely tuned Prussian blue-based nanoparticles and their application in disease treatment

Y. Gao, G. Yu, K. Xing, D. Gorin, Y. Kotelevtsev, W. Tong and Z. Mao, J. Mater. Chem. B, 2020, 8, 7121 DOI: 10.1039/D0TB01248C

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