Issue 21, 2024

Recent progress of UCNPs–MoS2 nanocomposites as a platform for biological applications

Abstract

Composite materials can take advantages of the functional benefits of multiple pure nanomaterials to a greater degree than single nanomaterials alone. The UCNPs–MoS2 composite is a nano-application platform that combines upconversion luminescence and photothermal properties. Upconversion nanoparticles (UCNPs) are inorganic nanomaterials with long-wavelength excitation and short-wavelength tunable emission capabilities, and are able to effectively convert near-infrared (NIR) light into visible light for increased photostability. However, UCNPs have a low capacity for absorbing visible light, whereas MoS2 shows better absorption in the ultraviolet and visible regions. By integrating the benefits of UCNPs and MoS2, UCNPs–MoS2 nanocomposites can convert NIR light with a higher depth of detection into visible light for application with MoS2 through fluorescence resonance energy transfer (FRET), which compensates for the issues of MoS2's low tissue penetration light-absorbing wavelengths and expands its potential biological applications. Therefore, starting from the construction of UCNPs–MoS2 nanoplatforms, herein, we review the research progress in biological applications, including biosensing, phototherapy, bioimaging, and targeted drug delivery. Additionally, the current challenges and future development trends of UCNPs–MoS2 nanocomposites for biological applications are also discussed.

Graphical abstract: Recent progress of UCNPs–MoS2 nanocomposites as a platform for biological applications

Article information

Article type
Review Article
Submitted
15 dic. 2023
Accepted
23 abr. 2024
First published
24 abr. 2024

J. Mater. Chem. B, 2024,12, 5024-5038

Recent progress of UCNPs–MoS2 nanocomposites as a platform for biological applications

Y. Wang, Y. Wang, H. Zhong, L. Xiong, J. Song, X. Zhang, T. He, X. Zhou, L. Li and D. Zhen, J. Mater. Chem. B, 2024, 12, 5024 DOI: 10.1039/D3TB02958A

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