Recent advances in dual photoredox/nickel catalyzed alkene carbofunctionalised reactions

Abstract

Alkene carbofunctionalization reactions have great potential for synthesizing complex molecules and constructing complex structures in natural products and medicinal chemistry. Recently, dual photoredox/nickel catalysis emerged as a novel strategy for alkene carbofunctionalization. Nickel offers numerous advantages over other transition metals, such as being cost-effective, abundant, and less toxic, and moreover, it has many oxidation states. The introduction of nickel catalysts exhibits excellent catalytic activity in dual photoredox/transition metal catalysis, facilitating the formation of carbon-carbon or carbon-heteroatom bonds in organic transformations. This review highlights the latest advancements in dual photoredox/nickel-catalyzed alkene carbofunctionalizations and this review includes the literature published from 2020 to 2024.