Issue 32, 2022

MXene-modified molecularly imprinted polymers as an artificial bio-recognition platform for efficient electrochemical sensing: progress and perspectives

Abstract

The development of efficient electrochemical sensors of exceptional features, molecularly imprinted polymers (MIPs), has been extensively utilized due to their great vitality as an alternative to bio-recognition elements. MIPs as an artificial bio-recognition element are getting significant attention due to their affordability, easy processability, and scaling-up capabilities. However, the challenge of longer stability and higher sensitivity associated with MIP-based sensing technology is still a remaining challenge. This can be addressed by modifying MIPs with electro-active nano-systems. Correspondingly, MXene is an emerging material of choice to make MIP-based sensing platforms more efficient and develop a bio-active-free sensing system. This review highlights state-of-the-art MXene-modified MIP electrochemical sensing platforms to overcome the associated limitations of pristine MIPs. As a proof-of-concept, the sensitive and selective detection of markers for health monitoring can be efficiently fulfilled by the high-performance MXene-MIP nanocomposite-based electrochemical sensor. Moreover, the challenges associated with this research area along with the potential solutions are also discussed. An attempt has been made to explore MXene-MIP nanocomposites as a next-generation sensing platform suitable for point-of-care testing (POCT) applications.

Graphical abstract: MXene-modified molecularly imprinted polymers as an artificial bio-recognition platform for efficient electrochemical sensing: progress and perspectives

  • This article is part of the themed collection: PCCP Reviews

Article information

Article type
Perspective
Submitted
23 may. 2022
Accepted
27 jul. 2022
First published
28 jul. 2022

Phys. Chem. Chem. Phys., 2022,24, 19164-19176

MXene-modified molecularly imprinted polymers as an artificial bio-recognition platform for efficient electrochemical sensing: progress and perspectives

A. Singhal, S. Yadav, Mohd. A. Sadique, R. Khan, A. K. Kaushik, N. Sathish and A. K. Srivastava, Phys. Chem. Chem. Phys., 2022, 24, 19164 DOI: 10.1039/D2CP02330J

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