Issue 13, 2021

Recent trends on burn wound care: hydrogel dressings and scaffolds

Abstract

Acute and chronic wounds can cause severe physical trauma to patients and also result in an immense socio-economic burden. Thus, wound management has attracted increasing attention in recent years. However, burn wound management is still a major challenge in wound management. Autografts are often considered the gold-standard for burn care, but their application is limited by many factors. Hence, ideal burn dressings and skin substitute dressings are desirable. With the development of biomaterials and progress of tissue engineering technology, some innovative dressings and tissue engineering scaffolds, such as nanofibers, films, foams and hydrogels, have been widely used in the field of biomedicine, especially in wound management. Among them, hydrogels have attracted tremendous attention with their unique advantages. In this review, we discuss the challenges in burn wound management, several crucial design considerations with respect to hydrogels for burn wound healing, and available polymers for hydrogels in burn wound care. In addition, the potential application and plausible prospect of hydrogels are also highlighted.

Graphical abstract: Recent trends on burn wound care: hydrogel dressings and scaffolds

Article information

Article type
Review Article
Submitted
17 mar. 2021
Accepted
14 may. 2021
First published
28 may. 2021

Biomater. Sci., 2021,9, 4523-4540

Recent trends on burn wound care: hydrogel dressings and scaffolds

Y. Yao, A. Zhang, C. Yuan, X. Chen and Y. Liu, Biomater. Sci., 2021, 9, 4523 DOI: 10.1039/D1BM00411E

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