Issue 9, 2019

Continuous-flow crystallisation in 3D-printed compact devices

Abstract

A flexible and cost-effective methodology to develop compact flow devices with heat exchange ability is presented here. Additive manufacturing techniques allow the rapid design and manufacture of modular jacketed flow devices, where heat exchange can be modelled and controlled to generate efficient devices for applications in continuous-flow cooling crystallisation. As a proof of concept, the crystallisation of paracetamol has been demonstrated. The manufactured devices are effective in crystallising form II paracetamol employing metacetamol as a co-crystallising agent.

Graphical abstract: Continuous-flow crystallisation in 3D-printed compact devices

Supplementary files

Article information

Article type
Paper
Submitted
11 may. 2019
Accepted
23 jul. 2019
First published
23 jul. 2019

React. Chem. Eng., 2019,4, 1682-1688

Continuous-flow crystallisation in 3D-printed compact devices

O. Okafor, K. Robertson, R. Goodridge and V. Sans, React. Chem. Eng., 2019, 4, 1682 DOI: 10.1039/C9RE00188C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements