Electrochemical sensor based on a three dimensional nanostructured MoS2 nanosphere-PANI/reduced graphene oxide composite for simultaneous detection of ascorbic acid, dopamine, and uric acid

Shuaihui Li; Yashen Ma; Yongkang Liu; Gu Xin; Minghua Wang; Zhihong Zhang; Zhongyi Liu

doi:10.1039/C8RA09511F

Electrochemical sensor based on a three dimensional nanostructured MoS₂ nanosphere-PANI/reduced graphene oxide composite for simultaneous detection of ascorbic acid, dopamine, and uric acid†

Shuaihui Li,^a Yashen Ma,^b Yongkang Liu,^b Gu Xin,*^c Minghua Wang,^b Zhihong Zhang

*^b and Zhongyi Liu

*^a

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* Corresponding authors

^a School of Chemical Engineering and Energy, Zhengzhou University, No. 100 Science Avenue, Zhengzhou 450001, Henan, China
E-mail: liuzhongyi@zzu.edu.cn, 2006025@zzuli.edu.cn
Tel: +86-37186609676

^b Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, China

^c College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, China
E-mail: guxin@zzu.edu.cn

Abstract

A three dimensional (3D) nanostructured composite based on the self-assembly of MoS₂ nanospheres and polyaniline (PANI) loaded on reduced graphene oxide (denoted by 3D MoS₂-PANI/rGO) was prepared via a feasible one-pot hydrothermal process. The 3D MoS₂-PANI/rGO nanocomposite not only exhibits good functionality and bioaffinity but also displays high electrochemical catalytic activity. As such, the developed 3D MoS₂-PANI/rGO nanocomposite can be employed as the sensing platform for simultaneously detecting small biomolecules, i.e., ascorbic acid (AA), dopamine (DA), and uric acid (UA). The peak currents obtained from the differential pulse voltammetry (DPV) measurements depended linearly on the concentrations in the wide range from 50 μM to 8.0 mM, 5.0 to 500 μM, and 1.0 to 500 μM, giving low detection limits of 22.20, 0.70, and 0.36 μM for AA, DA, and UA, respectively. Furthermore, the 3D MoS₂-PANI/rGO-based electrochemical sensor also exhibited high selectivity, good reproducibility and stability toward small molecule detection. The present sensing strategy based on 3D MoS₂-PANI/rGO suggests a good reliability in the trace determination of electroactive biomolecules.

This article is part of the themed collection: Sensors for health and happiness

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Article information

DOI: https://doi.org/10.1039/C8RA09511F
Article type: Paper
Submitted: 19 nov. 2018
Accepted: 15 ene. 2019
First published: 23 ene. 2019
This article is Open Access

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RSC Adv., 2019,9, 2997-3003

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Electrochemical sensor based on a three dimensional nanostructured MoS₂ nanosphere-PANI/reduced graphene oxide composite for simultaneous detection of ascorbic acid, dopamine, and uric acid

S. Li, Y. Ma, Y. Liu, G. Xin, M. Wang, Z. Zhang and Z. Liu, RSC Adv., 2019, 9, 2997 DOI: 10.1039/C8RA09511F

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