Issue 59, 2018

NaI-mediated divergent synthesis of isatins and isoindigoes: a new protocol enabled by an oxidation relay strategy

Abstract

A new approach for the synthesis of isatins and isoindigoes by an inexpensive and environmentally friendly NaI-mediated transformation is disclosed. The selectivity could be switched by simply varying the solvent, and isatins (using THF) and isoindigoes (using DMSO) could be obtained in moderate to excellent yields.

Graphical abstract: NaI-mediated divergent synthesis of isatins and isoindigoes: a new protocol enabled by an oxidation relay strategy

Supplementary files

Article information

Article type
Communication
Submitted
05 jun. 2018
Accepted
03 jul. 2018
First published
04 jul. 2018

Chem. Commun., 2018,54, 8265-8268

NaI-mediated divergent synthesis of isatins and isoindigoes: a new protocol enabled by an oxidation relay strategy

H. Zhang, Y. Wang, L. Huang, L. Zhu, Y. Feng, Y. Lu, Q. Zhao, X. Wang and Z. Wang, Chem. Commun., 2018, 54, 8265 DOI: 10.1039/C8CC04471F

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