Issue 6, 2017

Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(ii) ions

Abstract

Two simple fluorescent sensors for Cu(II) ions were synthesized in two reaction steps, using recently developed C–H functionalization reactions for boron dipyrrins, starting from a standard 8-aryl-BODIPY dye and a tris(2-aminoethyl)amine (TREN) ligand. At pH 5, the resulting BODIPY–TREN conjugates are demonstrated to be promising, highly selective, water soluble, Cu(II) sensors that can permeate the cell membrane.

Graphical abstract: Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(ii) ions

Supplementary files

Article information

Article type
Paper
Submitted
24 nov. 2016
Accepted
20 dic. 2016
First published
13 ene. 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 3066-3071

Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(II) ions

B. Verbelen, M. Valckenborgh, M. Inclán, A. Nebot, W. Dehaen and E. García-España, RSC Adv., 2017, 7, 3066 DOI: 10.1039/C6RA27299A

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