Issue 28, 2016

Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells

Abstract

A novel pyrano[3,2-c]julolidin-2-one based fluorescent molecular rotor PYJO4 has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg2+ in live cells. The probe operates via a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb. PYJO4 coated test strips can be used to detect mercury ions in contaminated water.

Graphical abstract: Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells

Supplementary files

Article information

Article type
Paper
Submitted
07 jun. 2016
Accepted
17 jun. 2016
First published
17 jun. 2016

J. Mater. Chem. B, 2016,4, 4934-4940

Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells

A. K. Jha, S. Umar, R. K. Arya, D. Datta and A. Goel, J. Mater. Chem. B, 2016, 4, 4934 DOI: 10.1039/C6TB01413E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements