Issue 21, 2011

Modular ‘click’ sensors for zinc and their application in vivo

Abstract

Although the central role that zinc plays in many biological processes and important disease states is now well-established, there remains a pressing need to develop an absolute understanding of the underlying biology of zinc trafficking in terms of its dynamic and quantitative processing in specific organelles. Here we describe the modular synthesis of zinc sensors using a ‘click’ approach and demonstrate the applicability of our new sensors in vivo using a zebrafish model.

Graphical abstract: Modular ‘click’ sensors for zinc and their application in vivo

Supplementary files

Article information

Article type
Communication
Submitted
28 feb. 2011
Accepted
31 mar. 2011
First published
28 abr. 2011

Chem. Commun., 2011,47, 6036-6038

Modular ‘click’ sensors for zinc and their application in vivo

K. Jobe, C. H. Brennan, M. Motevalli, S. M. Goldup and M. Watkinson, Chem. Commun., 2011, 47, 6036 DOI: 10.1039/C1CC11213A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements