Issue 99, 2023

Photochemical reductive deamination of alpha-amino aryl alkyl ketones

Abstract

Photochemical reductive deamination of alpha-amino aryl alkyl ketones under photosensitizer-free conditions is presented. This protocol features high efficiency and selectivity. A plausible reaction pathway is proposed based on ultraviolet–visible absorption investigation, control experiments and deuterium-labelling studies. Mechanistic study reveals that the alpha-hydrogen atom of the ketone product originated from water.

Graphical abstract: Photochemical reductive deamination of alpha-amino aryl alkyl ketones

Supplementary files

Article information

Article type
Communication
Submitted
29 sep. 2023
Accepted
15 nov. 2023
First published
16 nov. 2023

Chem. Commun., 2023,59, 14685-14688

Photochemical reductive deamination of alpha-amino aryl alkyl ketones

J. Liang, Y. Su and Y. Zou, Chem. Commun., 2023, 59, 14685 DOI: 10.1039/D3CC04837C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements