Photo-crosslinked integrated triphasic scaffolds with gradient composition and strength for osteochondral regeneration

Wenzhao Wang, Hui Li, Ping Song, Yanbo Guo, Di Luo, Hao Li and Liang Ma

J. Mater. Chem. B, 2024, 12, 1271
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A triphasic biomimetic BMSC-loaded scaffold for osteochondral integrated regeneration in rabbits and pigs

Zhaoyi Wang, Wangbei Cao, Fanghui Wu, Xiurong Ke, Xinyu Wu, Tong Zhou, Jun Yang, Guojing Yang, Cheng Zhong, Zhongru Gou and Changyou Gao

Biomater. Sci., 2023, 11, 2924
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Bionic gradient scaffolds for osteochondral tissue engineering: construction strategies, interface optimization, gradient characterization, and controllability research

Fufen Li, Xiaohan Yang, Yining Chen, Min Gong, Lang Li, Anjing Chen, Nianhua Dan and Zhengjun Li

Biomater. Sci., 2026, 14, 305
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3D printing of customized bioceramics for promoting bone tissue regeneration by regulating sympathetic nerve behavior

Zixuan Su, Chuan Guo, Xingyu Gui, Lina Wu, Boqing Zhang, Yuxiang Qin, Zhen Tan, Changchun Zhou, Wei Wei, Yujiang Fan and Xingdong Zhang

J. Mater. Chem. B, 2024, 12, 4217
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3D bio-printing of photocrosslinked anatomically tooth-shaped scaffolds for alveolar ridge preservation after tooth extraction

Haihuan Gong, Yanyan Zhao, Qiwei Chen, Yilin Wang, Hong Zhao, Jing Zhong, Qing Lan, Ying Jiang and Wenhua Huang

J. Mater. Chem. B, 2022, 10, 8502
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Real-time visualizing cartilage-targeted catalytic nanomedicine designed from black phosphorus nanosheets for enhanced BMSC chondrogenic differentiation and in vivo antioxidative therapy

Jize Dong, Chunfeng Song, Moran Huang, Zhen Peng, Luze Shi, Yaying Sun, Jiwu Chen and Xingyu Zhang

Applied Materials Today, 2024, 41, 102436
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Osteochondral tissue engineering‑based subchondral bone plate repair (Review)

Xiaoyang Zhang, Weibo Jiang, Quezhu Danzeng, Yi Shen and Mengying Cui

Mol Med Rep, 2025, 31, 1
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Engineered Osteochondral Scaffolds with Bioactive Cartilage Zone for Enhanced Articular Cartilage Regeneration

Aleksandra A. Golebiowska, Jonathon T. Intravaia, Vinayak Sathe, Sangamesh G. Kumbar and Syam P. Nukavarapu

Ann Biomed Eng, 2025, 53, 597
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A Hierarchical 3D Graft Printed with Nanoink for Functional Craniofacial Bone Restoration

Yang Shi, Jue Shi, Yuan Sun, Qiqi Liu, Chun Zhang, Changyu Shao, Kang Yu, Mingjie Ge, Rui Mi, Jingyi Gu, Wenzhi Wu, Weiying Lu, Zhuo Chen, Yong He, Ruikang Tang and Zhijian Xie

Adv Funct Materials, 2023, 33
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Gradient scaffolds for osteochondral tissue engineering and regeneration

Ziqi Xiong, Fangyuan Hong, Zhonglin Wu, Yijia Ren, Nuola Sun, Boon Chin Heng and Jing Zhou

Chemical Engineering Journal, 2024, 498, 154797
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In situ swelling of low-friction, high load-bearing self-bending bilayer hydrogels inspired by articular cartilage

Jianfeng Chen, Chuan Li, Xiaoxiao Chen, Kui Zhou, Hanjing Li, Kai Peng, Yinong Yang, Yichuan Dai and Ben Huang

Biomed. Mater., 2025, 20, 025018
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The current status of nano-hydrogel preparations for osteochondral repair: Systematic Review

Abebe Feyissa Amhare, Lichun Qiao, Huan Deng, Jinyan Lin, Jun Wang, Wei Wang and Jing Han

Front. Bioeng. Biotechnol., 2025, 13
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A bilayer bioengineered patch with sequential dual-growth factor release to promote vascularization in bladder reconstruction

Jian Zhao, Haoqian Zhang, Zhengyun Ling, Ziyan An, Shuwei Xiao, Pengchao Wang, Zhouyang Fu, Jinpeng Shao, Yanfeng Sun and Weijun Fu

Regenerative Biomaterials, 2024, 11
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Recent development in multizonal scaffolds for osteochondral regeneration

Le Yu, Sacha Cavelier, Brett Hannon and Mei Wei

Bioactive Materials, 2023, 25, 122
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Osteochondral Interface: Regenerative Engineering and Challenges

Nuh Yildirim, Amina Amanzhanova, Gulzada Kulzhanova, Fariza Mukasheva and Cevat Erisken

ACS Biomater. Sci. Eng., 2023, 9, 1205
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Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1

Hai Liu, Weilun Pan, Honglin Liu, Denghui Xie and Liqiong Liao

International Journal of Biological Macromolecules, 2024, 257, 128481
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Fiber-reinforced hydrogel combined with 3D printed scaffolds for regeneration of osteochondral defects

Huan Liu, Yichen Dou, Jiawei Wei, Shiqi Xiao, Shue Jin, Li Yuan, Jing Wen, Jiangshan Liu, Yubao Li and Jidong Li

Materials Chemistry and Physics, 2025, 335, 130532
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Advances in the Development of Gradient Scaffolds Made of Nano-Micromaterials for Musculoskeletal Tissue Regeneration

Lei Fang, Xiaoqi Lin, Ruian Xu, Lu Liu, Yu Zhang, Feng Tian, Jiao Jiao Li and Jiajia Xue

Nano-Micro Lett., 2025, 17
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Functional hydrogels for the repair and regeneration of tissue defects

Xinlin Li, Mengfei Xu, Zhaoli Geng and Yi Liu

Front. Bioeng. Biotechnol., 2023, 11
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Recent research trends in gradient hydrogels for various biomedical applications

Do Young Jung, Mina Kwon and Ki Su Kim

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4D biofabrication of functionally gradient hydrogels: A pathway to morphogenetic tissue engineering

Jian Zhang, Guodong Wu and Aixiang Ding

Chemical Engineering Journal, 2025, 522, 167810
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Recent Methods for Modifying Mechanical Properties of Tissue-Engineered Scaffolds for Clinical Applications

Andrew Johnston and Anthony Callanan

Biomimetics, 2023, 8, 205
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3D printing of personalized magnesium composite bone tissue engineering scaffold for bone and angiogenesis regeneration

Wenzhao Wang, Ling Wang, Boqing Zhang, Shenghui Shang, Chenxi Zhao, Wencan Zhang, Jing Chen, Changchun Zhou, Hengxing Zhou and Shiqing Feng

Chemical Engineering Journal, 2024, 484, 149444
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Biomimetic bone cartilage scaffolds based on trilayer methacrylated hydroxyapatite/GelMA composites for full-thickness osteochondral regeneration

Yu Zhong, Xia Cao, Ming Huang, Yun Lei and Ai-Lin Liu

International Journal of Biological Macromolecules, 2025, 298, 139860
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Functionally Designed Liquid Crystal Elastomer Foams for Cartilage Regeneration

Cancan Du, Zhongcheng Liu and Yan Xu

Adv Funct Materials, 2026, 36
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Novel multi-component synergistic bioink that balances biocompatibility and mechanical strength for cartilage regeneration

Zijun Ma, Wendan Jia, Xiaoyuan Wang, Rong Cheng, Lu Han, Meng Li, Xiaoning Yang and Shengbo Sang

J. Zhejiang Univ. Sci. B, 2025, 26, 1156
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A new strategy for intervertebral disc regeneration: The synergistic potential of mesenchymal stem cells and their extracellular vesicles with hydrogel scaffolds

Yan Zhao, Huaize Dong, Qiuqiu Xia, Yanyang Wang, Lu Zhu, Zongyue Hu, Jiyue Xia, Qiming Mao, Zijing Weng, Jiangbi Yi, Shuai Feng, Youhong Jiang, Wenbo Liao and Zhijun Xin

Biomedicine & Pharmacotherapy, 2024, 172, 116238
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Gradient hydrogels: From fabrication strategies, reinforcement mechanisms, to biomedical applications

Yufei Yong, Lianghao Jia, Hongrong Wu, Tao Xiang and Shaobing Zhou

Chemical Engineering Journal, 2025, 522, 167390
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κ‐Carrageenan Scaffolds Incorporating Hydroxyapatite‐Coated Chitosan Nanoparticles for Bone Tissue Engineering and Controlled Rosuvastatin Release

Mohammad Salmani Mobarakeh, Monireh Kouhi, Legha Ansari, Sayedeh Boshra Sadat, Saman Savabi, Farahnaz Nejatidanesh and Rahmatollah Emadi

Macromolecular Bioscience, 2026, 26
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Gelatin methacryloyl hydrogel with and without dental pulp stem cells for TMJ regeneration: An in vivo study in rabbits

Joao Luiz Monteiro, Toru Takusagawa, Gerhilde C. Sampaio, Helen He, Emanuel D. de Oliveira e Silva, Belmiro C. E. Vasconcelos, Joseph P. McCain, Robert W. Redmond, Mark A. Randolph and Fernando P. S. Guastaldi

J of Oral Rehabilitation, 2024, 51, 394
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Fused Deposition Modeling Printed PLA/Nano β-TCP Composite Bone Tissue Engineering Scaffolds for Promoting Osteogenic Induction Function

Wenzhao Wang, Pan Liu, Boqing Zhang, Xingyu Gui, Xuan Pei, Ping Song, Xia Yu, Zhengdong Zhang and Changchun Zhou

IJN, 2023, Volume 18, 5815
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SLA-3d printed building and characteristics of GelMA/HAP biomaterials with gradient porous structure

Qinghua Chen, Bin Zou, Xinfeng Wang, Xingguo Zhou, Gongxian Yang, Qingguo Lai and Yun Zhao

Journal of the Mechanical Behavior of Biomedical Materials, 2024, 155, 106553
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Polysaccharide-Based Composite Hydrogel with Hierarchical Microstructure for Enhanced Vascularization and Skull Regeneration

Gonggong Lu, Xiang Li, Peilei Wang, Xing Li, Yuxiang Wang, Jiayi Zhu, Alfredo Ronca, Ugo D’Amora, Wenke Liu and Xuhui Hui

Biomacromolecules, 2023, 24, 4970
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3D printing of lithium osteogenic bioactive composite scaffold for enhanced bone regeneration

Wenzhao Wang, Jianlu Wei, Dong Lei, Suning Wang, Boqing Zhang, Shenghui Shang, Baoshuai Bai, Chenxi Zhao, Wencan Zhang, Changchun Zhou, Hengxing Zhou and Shiqing Feng

Composites Part B: Engineering, 2023, 256, 110641
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