A ferrocene-containing analogue of the MCU inhibitor Ru265 with increased cell permeability

Zhouyang Huang, Jesse A. Spivey, Samantha N. MacMillan and Justin J. Wilson

Inorg. Chem. Front., 2023, 10, 591
DOI: 10.1039/D2QI02183H

Supramolecular delivery of dinuclear ruthenium and osmium MCU inhibitors

Nicholas P. Bigham, Robyn J. Novorolsky, Keana R. Davis, Haipei Zou, Samantha N. MacMillan, Michael J. Stevenson, George S. Robertson and Justin J. Wilson

Inorg. Chem. Front., 2024, 11, 5064
DOI: 10.1039/D4QI01102C

Dinuclear nitrido-bridged osmium complexes inhibit the mitochondrial calcium uniporter and protect cortical neurons against lethal oxygen–glucose deprivation

Joshua J. Woods, Robyn J. Novorolsky, Nicholas P. Bigham, George S. Robertson and Justin J. Wilson

RSC Chem. Biol., 2023, 4, 84
DOI: 10.1039/D2CB00189F

MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology

Jin Wang, Jinyong Jiang, Haoliang Hu and Linxi Chen

Journal of Advanced Research, 2025, 68, 271
DOI: 10.1016/j.jare.2024.02.013

Insight of the role of mitochondrial calcium homeostasis in hepatic insulin resistance

Zhanchen Dong and Xiaofeng Yao

Mitochondrion, 2022, 62, 128
DOI: 10.1016/j.mito.2021.11.007

Coordination chemistry of emerging Meitner-Auger electron-emitting radiometals for targeted radionuclide therapy

Grant J. Stec and Justin J. Wilson

Coordination Chemistry Reviews, 2025, 542, 216764
DOI: 10.1016/j.ccr.2025.216764

A Fluorogenic Inhibitor of the Mitochondrial Calcium Uniporter

Zhouyang Huang, Samantha N. MacMillan and Justin J. Wilson

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202214920

Investigation of Cobalt(III) Cage Complexes as Inhibitors of the Mitochondrial Calcium Uniporter

Nicholas P. Bigham and Justin J. Wilson

Eur J Inorg Chem, 2023, 26
DOI: 10.1002/ejic.202200735

Employing phosphonate and phosphinate ligands for prodrug development of the mitochondrial calcium uniporter inhibitor Ru265

Haipei Zou, Samantha N. MacMillan and Justin J. Wilson

Journal of Inorganic Biochemistry, 2026, 275, 113145
DOI: 10.1016/j.jinorgbio.2025.113145

Mitochondrial Ca2+ in Cancer Growth and Metabolism

Jillian S. Weissenrieder and J. Kevin Foskett

Journal Cellular Physiology, 2025, 240
DOI: 10.1002/jcp.70093

Structure‐Activity Relationships of Metal‐Based Inhibitors of the Mitochondrial Calcium Uniporter

Zhouyang Huang and Justin J. Wilson

ChemMedChem, 2023, 18
DOI: 10.1002/cmdc.202300106

Chemical Structure Elucidation in the Development of Inorganic Drugs: Evidence from Ru‐, Au‐, As‐, and Sb‐based Medicines

Alissa Lance‐Byrne, Brent Lindquist‐Kleissler and Timothy C. Johnstone

Eur J Inorg Chem, 2024, 27
DOI: 10.1002/ejic.202300717

EXAFS Analysis of Ru265 and Ru360 in Human Blood

Ani T. Baker, James H. Lovett, Haipei Zou, Justin J. Wilson and Hugh H. Harris

Inorg. Chem., 2026, 65, 3606
DOI: 10.1021/acs.inorgchem.5c05608

Mitochondria modulate ameloblast Ca2+ signaling

Veronica Costiniti, Guilherme H. S. Bomfim, Maria Neginskaya, Ga‐Yeon Son, Erna Mitaishvili, Marta Giacomello, Evgeny Pavlov and Rodrigo S. Lacruz

The FASEB Journal, 2022, 36
DOI: 10.1096/fj.202100602R

A [1H,15N] Heteronuclear Single Quantum Coherence NMR Study of the Solution Reactivity of the Ruthenium‐Based Mitochondrial Calcium Uniporter Inhibitor Ru265

Joshua J. Woods, Jesse A. Spivey and Justin J. Wilson

Eur J Inorg Chem, 2022, 2022
DOI: 10.1002/ejic.202100995

The mitochondrial calcium uniporter: Balancing tumourigenic and anti‐tumourigenic responses

Danielle M. Colussi and Peter B. Stathopulos

The Journal of Physiology, 2024, 602, 3315
DOI: 10.1113/JP285515

Carboxylate-Capped Analogues of Ru265 Are MCU Inhibitor Prodrugs

Nicholas P. Bigham, Zhouyang Huang, Jesse Spivey, Joshua J. Woods, Samantha N. MacMillan and Justin J. Wilson

Inorg. Chem., 2022, 61, 17299
DOI: 10.1021/acs.inorgchem.2c02930

A Fluorogenic Inhibitor of the Mitochondrial Calcium Uniporter

Zhouyang Huang, Samantha N. MacMillan and Justin J. Wilson

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202214920

Metal Coordination Complexes as Therapeutic Agents for Ischemia-Reperfusion Injury

Nicholas P. Bigham and Justin J. Wilson

J. Am. Chem. Soc., 2023, 145, 9389
DOI: 10.1021/jacs.3c01984