Native carboxyl group-assisted C–H acetoxylation of hydrocinnamic and phenylacetic acids

Xinchao Wang, Hang Wang, Chunlin Zhou, Lei Yang, Lei Fu and Gang Li

Chem. Commun., 2022, 58, 4993
DOI: 10.1039/D2CC00459C

Multiple-fold C–F bond functionalization for the synthesis of (hetero)cyclic compounds: fluorine as a detachable chemical handle

Danhua Ge and Xue-Qiang Chu

Org. Chem. Front., 2022, 9, 2013
DOI: 10.1039/D1QO01749G

Transition-metal-catalyzed asymmetric defluorinative reactions

Danhua Ge, Jia-Wei Chen, Yu-Lan Chen, Mengtao Ma, Zhi-Liang Shen and Xue-Qiang Chu

Org. Chem. Front., 2023, 10, 3909
DOI: 10.1039/D3QO00751K

Four-component defluorinative reaction of allylic fluorides, amidines, and Cs2CO3under transition-metal-free conditions

Yu-Lan Chen, Li-Wen Sun, Jia-Wei Chen, Ming-Quan Zhu, Mengtao Ma, Zhi-Liang Shen and Xue-Qiang Chu

Green Chem., 2022, 24, 6816
DOI: 10.1039/D2GC02045A

Ruthenium-catalysed cross-coupling reaction of ketones with transformable directing groups as alkenyl electrophiles

Yuya Kogure, Kohei Hatakeyama, Kai Tsuchiya, Yuta Kunii and Satoshi Ueno

Chem. Commun., 2023, 59, 12463
DOI: 10.1039/D3CC04265K

Suppressing hydrodechlorination in PC–Ni cocatalyzed C–N and C–O coupling reactions

Bo Yang, Hu Zhang, Yi-Ming Chen, Jian-Ping Qu and Yan-Biao Kang

Org. Chem. Front., 2025, 12, 5896
DOI: 10.1039/D5QO00660K

Divergent C(sp2)–H arylation of heterocycles via organic photoredox catalysis

Jie Ren, Chao Pi, Xiuling Cui and Yangjie Wu

Green Chem., 2022, 24, 3017
DOI: 10.1039/D1GC04825B

Transition-metal-free and base promoted C–C bond formation via C–N bond cleavage of organoammonium salts

Tao Zhang, Kunyu Wang, Yuting Ke, Yuanyuan Tang, Long Liu, Tianzeng Huang, Chunya Li, Zhi Tang and Tieqiao Chen

Org. Biomol. Chem., 2021, 19, 8237
DOI: 10.1039/D1OB01468D

Carbon–carbon bond activation by B(OMe)3/B2pin2-mediated fragmentation borylation

Li Wang, Qi Zhong, Youliang Zou, Youzhi Yin, Aizhen Wu, Quan Chen, Ke Zhang, Jiachen Jiang, Mengzhen Zhao and Hua Zhang

Chem. Sci., 2021, 12, 15104
DOI: 10.1039/D1SC04487G

Conceptual advances in nucleophilic organophosphine-promoted transformations

Lona Dutta, Atanu Mondal, Jay Prakash Maurya, Dipto Mukhopadhyay and S. S. V. Ramasastry

Chem. Commun., 2023, 59, 11045
DOI: 10.1039/D3CC03648K

Ni-catalyzed reductive cross-couplings of diaryl disulfides with aryl bromides for biaryl synthesis through C–S bond cleavage

Xuan-Qi Zhang, Cai-Yu He, Shuang-Feng Song, Xue-Qiang Chu, Hao Xu, Xiaocong Zhou, Weidong Rao and Zhi-Liang Shen

Org. Chem. Front., 2025, 12, 5459
DOI: 10.1039/D5QO00546A

A DFT mechanistic study on nickel-catalyzed arylation of amino alcohols with aryl electrophiles: insights into the origins of chemoselectivity

Chao Shan, Zhiqiang Zhang, Junyan You, Ranran Li and Xuexiang Ma

Catal. Sci. Technol., 2025, 15, 1634
DOI: 10.1039/D4CY01460J

Copper-catalyzed enantioselective diyne cyclizationviaC(sp2)–O bond cleavage

Ji-Jia Zhou, Ya-Nan Meng, Li-Gao Liu, Yi-Xi Liu, Zhou Xu, Xin Lu, Bo Zhou and Long-Wu Ye

Chem. Sci., 2023, 14, 3493
DOI: 10.1039/D2SC06152J

Carboxyl group assisted isodesmicmeta-C–H iodination of phenethylamines, benzylamines, and 2-aryl anilines

Lei Yang, Xinchao Wang, Meng Zhang, Shangda Li, Xinqiang Fang and Gang Li

Org. Chem. Front., 2023, 10, 3760
DOI: 10.1039/D3QO00479A

Cross-coupling of organic fluorides with allenes: a silyl-radical-relay pathway for the construction of α-alkynyl-substituted all-carbon quaternary centres

Jun Zhou, Zhengyu Zhao, Soichiro Mori, Katsuhiro Yamamoto and Norio Shibata

Chem. Sci., 2024, 15, 5113
DOI: 10.1039/D3SC06617G

Metal-free C–H borylation of heterocycles by merging photoredox and hydrogen atom transfer catalysis

Changfu Wu, Shuang Luo, Xiaozu Liu and Peijun Liu

Org. Chem. Front., 2024, 11, 4785
DOI: 10.1039/D4QO01041H

Fluorescent coumarin-alkynes for labeling of amino acids and peptides via manganese(i)-catalyzed C–H alkenylation

Adelina Kopp, Tsuyoshi Oyama and Lutz Ackermann

Chem. Commun., 2024, 60, 5423
DOI: 10.1039/D4CC00361F

Nickel-catalyzed cross-electrophile coupling of aryl thiols with aryl bromides via C–S bond activation

Hao Xu, Cai-Yu He, Bo-Jie Huo, Jia-Wen Jing, Chengping Miao, Weidong Rao, Xue-Qiang Chu, Xiaocong Zhou and Zhi-Liang Shen

Org. Chem. Front., 2023, 10, 5171
DOI: 10.1039/D3QO01236K

Visible light-induced metal-free chemoselective oxidative cleavage of benzyl C–heteroatom (N, S, Se) bonds utilizing organoboron photocatalysts

Lanfeng Wei, Wenbo Bai, Zhiyan Hu, Zhiyong Yang and Liang Xu

Chem. Commun., 2023, 59, 13344
DOI: 10.1039/D3CC04073A

A regioselective, convergent, and additive-free approach for the synthesis of pyrido[1,4]oxazocines

Kai-Qiang Tian, Tongbo Zhang, Shi-Jiao Zhang, Jun Zhao, Leilei Mao, Guiyun Duan and Hong-Shuang Li

New J. Chem., 2023, 47, 18193
DOI: 10.1039/D3NJ03776B

Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters

Xiaodong Gu, Kexin Liu, Limin Yang, Chengyi Xie, Mingliang Li and Jun (Joelle) Wang

Chem. Sci., 2022, 13, 12498
DOI: 10.1039/D2SC03409C

HFIP-promoted para-selective alkylation of anilines and phenols with tertiary alkyl bromides

Pengcheng Huang, Xipeng Jiang, Du Gao, Cheng Wang, Da-Qing Shi and Yingsheng Zhao

Org. Chem. Front., 2023, 10, 2476
DOI: 10.1039/D3QO00342F

Defluorophosphorylation of fluoroalkyl peroxides for the synthesis of highly substituted furans

Xue-Qiang Chu, Song-Zhou Cai, Jia-Wei Chen, Zi-Lun Yu, Mengtao Ma, Patrick J. Walsh and Zhi-Liang Shen

Green Chem., 2023, 25, 2000
DOI: 10.1039/D2GC04512E

Benzothiazolium salts as versatile primary alcohol derivatives in Ni-catalyzed cross-electrophile arylation/vinylation

Cheng Ye, Quan Lin, Yunrong Chen, Fan Wu and Hegui Gong

Org. Biomol. Chem., 2025, 23, 1596
DOI: 10.1039/D4OB01762E

Photoinduced aerobic C–S borylation of aryl sulfides

Xinqi Li, Zhen Wan, Xiaoyun Hu and Hua Zhang

Org. Chem. Front., 2022, 9, 3034
DOI: 10.1039/D2QO00240J

Deaminative radical reactions via relayed proton-coupled electron transfer

Qianqian Shi, Kuohong Chen, Limin Guo, Lili Han, Donghui Wei and Yu Lan

Org. Chem. Front., 2023, 10, 2155
DOI: 10.1039/D3QO00192J

Theoretical investigation on the mechanism of Ni0(acetylide carbanion)-ate complex-catalyzed C(sp2)–F bond activation and the origin of the counterion effect on reactivity

Xiao-Xia You, Ling-Qi Meng, Xu Liu, Li-Li Wang, Xin-Cheng Xu, Rong-Lin Zhong and Zhong-Min Su

Org. Chem. Front., 2026, 13, 2341
DOI: 10.1039/D5QO01757B

Heterocycles from cyclopropenones

Ashraf A. Aly, Alaa A. Hassan, Sara M. Mostafa, Asmaa. H. Mohamed, Esraa M. Osman and AbdElAziz A. Nayl

RSC Adv., 2022, 12, 18615
DOI: 10.1039/D2RA03011J

Catalytic asymmetric defluorinative allylation of silyl enol ethers

Jordi Duran, Javier Mateos, Albert Moyano and Xavier Companyó

Chem. Sci., 2023, 14, 7147
DOI: 10.1039/D3SC01498C

Cross-conjugated vinylogous annulation of π-CF3-allyl Pd-complexes with 4-methyl-3-trifluoroacetyl-quinolones

Chiliveru Priyanka, Desagoni Madhu, Palivela Siva Gangadhar, Lingamallu Giribabu and Nagender Punna

Chem. Commun., 2024, 60, 12233
DOI: 10.1039/D4CC03953J

Palladium-catalyzed α-arylation of sulfoxonium ylides with aryl fluorosulfates

Qing-Dong Wang, Jing-Ao Ren, Xu-Rong Cao, Xiaocong Zhou, Jin-Ming Yang and Zhi-Liang Shen

Org. Biomol. Chem., 2025, 23, 1412
DOI: 10.1039/D4OB01694G

Decarbonylative cycloaddition of 1H-indene-1,2,3-trione and norbornene via rhodium(i)-catalyzed carbon–carbon bond cleavage

Zhenzhu Hu, Yuhang Wang, Peng Ma, Jianhui Wang and Guiyan Liu

New J. Chem., 2022, 46, 11108
DOI: 10.1039/D2NJ01708C

Palladium-catalyzed α-arylation/β-elimination of sulfones

Mengzhao Yu, Luqiong Duan, Xinwei Zhang, Qian Zhang, Hongzhen Wang and Xiaolei Huang

New J. Chem., 2024, 48, 1062
DOI: 10.1039/D3NJ04668K

Enabling the Use of Alkyl Thianthrenium Salts in Cross‐Coupling Reactions by Copper Catalysis

Cheng Chen, Minyan Wang, Hongjian Lu, Binlin Zhao and Zhuangzhi Shi

Angewandte Chemie, 2021, 133, 21924
DOI: 10.1002/ange.202109723

Directing group assisted rhodium-catalyzed formal C–H arylation and carbonylative arylation of arenes with aryl halides in the presence of CO

Houyun Teng, Xiaoyuan Shao, Zheng-Feng Zhang, Ke-Fang Yang, Ming-Der Su, Li-Wen Xu and Lei Yang

Journal of Catalysis, 2024, 429, 115234
DOI: 10.1016/j.jcat.2023.115234

Addition of Alcohols onto Electron-Deficient Heteroarenium Salts: A Reversible Covalent Bonding Process under Basic Conditions

Baoli Chen, En Li, Feifei Song, Nicolas Guimond, Jiean Chen and Yong Huang

Synlett, 2023, 34, 1042
DOI: 10.1055/a-2005-5372

Cross-Electrophile Couplings of Benzyl Sulfonium Salts with Thiosulfonates via C–S Bond Activation

Xuan-Bo Hu, Yuwei Chen, Chen-Long Zhu, Hao Xu, Xiaocong Zhou, Weidong Rao, Xiao-Chun Hang, Xue-Qiang Chu and Zhi-Liang Shen

J. Org. Chem., 2024, 89, 13601
DOI: 10.1021/acs.joc.4c01786

Iron‐Mediated Desulfonylative Cross‐Electrophile Couplings of Heteroaryl Sulfones with Thiosulfonates for Efficient Synthesis of Heteroaryl Sulfides

Yuan He, Jie Pan, Ying Yan, Xue‐Qiang Chu, Hao Xu, Chengping Miao, Weidong Rao and Zhi‐Liang Shen

Chin. J. Chem., 2025, 43, 2151
DOI: 10.1002/cjoc.70092

Recent advances in single-atom catalysts for efficient C–C and C-heteroatom bonds formation

Xiaolong Guo, Zekun Bai, Zhenyu He, Yang Tian and Sihui Zhan

Sci. China Chem., 2026, 69, 1580
DOI: 10.1007/s11426-025-2996-6

Bridging the Gap between Bioreduction and Ullmann Homocoupling for Continuous-Flow Chemoenzymatic Cascades

Pengbo Liu, Weixi Kong, Liya Zhou, Zhongxu Guo, Li Ma, Ying He, Guanhua Liu, Yanjun Jiang and Yunting Liu

ACS Sustainable Chem. Eng., 2025, 13, 8939
DOI: 10.1021/acssuschemeng.5c00824

Direct Cross-Couplings of Aryl Nonaflates with Aryl Bromides under Nickel Catalysis

Hao Xu, Jia-Wen Jing, Yu-Bing Chen, Yong-Qing Xu, Xue-Qiang Chu, Xiaocong Zhou, Weidong Rao and Zhi-Liang Shen

J. Org. Chem., 2025, 90, 2341
DOI: 10.1021/acs.joc.4c02777

Palladium-Catalyzed Cross-Couplings of Aryl Thianthrenium Salts with N-Tosylhydrazones for the Synthesis of 1,1-Diarylalkenes

Qian-Qian Fu, Sheng-Bo Zhang, Shuang-Feng Song, Xue-Qiang Chu, Hao Xu, Chengping Miao, Weidong Rao and Zhi-Liang Shen

Org. Lett., 2025, 27, 11953
DOI: 10.1021/acs.orglett.5c04036

Advances in Synthetic Strategies for Indolo[2,1‐a]isoquinoline Derivatives

Qinghan Li, Lirong Han, Hui Zhou, Jinsong Hou and Xiaohao Shi

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.202500035

Bifunctional Photoactive Chiral Ligands Enable Visible‐Light‐Induced Nickel‐Catalyzed Enantioselective C−O Coupling

Junjie Xue, Lei Su, Weiwei Fang, Shen Gao, Qingshu Zheng and Jiawang Liu

Angew Chem Int Ed, 2026, 65
DOI: 10.1002/anie.202523823

Novel highly utilized PdNi bimetallic-loaded N-doped carbon catalysts prepared from MOF for Suzuki coupling reaction and hydro reduction of nitroaromatics

Yanjie Jiang, Siyu Han, Gongshu Wang, Zhangpei Chen, Ping Li and Jianshe Hu

Journal of Environmental Chemical Engineering, 2024, 12, 113324
DOI: 10.1016/j.jece.2024.113324

Photo-Promoted Decarboxylative Arylation of 3-Indoleacetic Acids for the Synthesis of Indole-Containing Diarylmethanes

Jiaxin Wang, Xiaofeng Wu, Weiya Kong, Jiacheng Li, Xingang Yao and Xiaodong Tang

J. Org. Chem., 2026, 91, 4306
DOI: 10.1021/acs.joc.5c03166

Visible-Light Photoredox-Catalyzed Dicarbofunctionalization of Styrenes with Oxime Esters and CO2: Multicomponent Reactions toward Cyanocarboxylic Acids and γ-Keto Acids

Junxue Bai, Miao Li, Cong Zhou, Yu Sha, Jiang Cheng, Jianwei Sun and Song Sun

Org. Lett., 2021, 23, 9654
DOI: 10.1021/acs.orglett.1c03938

Photoinduced Reduction of Nitroarenes and Tandem C–N Cross-Coupling with Haloarenes

Haoshi Bao and Leifeng Wang

Org. Lett., 2023, 25, 8872
DOI: 10.1021/acs.orglett.3c03656

Photo‐ and Cerium‐Mediated C─C Bond Cleavage for the Deconstructive Diversification of Cyclic Acids

Yan Xu, Jianjie Wang, Qian Zhang, Xinyao Hu, Chun Lv, Heng Yang, Bin Sun and Can Jin

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202500561

Well-defined (NHC)PdCl2(azetidine) complexes: Synthesis, characterization and catalytic activities

Jin Yang

Journal of Molecular Structure, 2023, 1294, 136463
DOI: 10.1016/j.molstruc.2023.136463

Exploration on Metal-Catalytic Conversion of Sulfinyl Sulfones

Yilong Li, Lulu Liu, Dingjian Shan, Fangcan Liang, Shuo Wang, Le Yu, Ji-Quan Liu, Qingling Wang, Xinxin Shao and Dianhu Zhu

ACS Catal., 2023, 13, 13474
DOI: 10.1021/acscatal.3c03663

Allylic and Vinylic Carbon-Fluorine Bond Activation via Transition Metal-Mediated and -Catalyzed Fluorine Elimination

Takeshi Fujita

J. Synth. Org. Chem. Jpn., 2024, 82, 130
DOI: 10.5059/yukigoseikyokaishi.82.130

Nickel-Catalyzed Direct Cross-Coupling of Aryl Thioether with Aryl Bromide

Na-Na Ma, Xuan-Bo Hu, Yuan-Shuai Wu, Ya-Wen Zheng, Mengtao Ma, Xue-Qiang Chu, Hao Xu, Haiqing Luo and Zhi-Liang Shen

Org. Lett., 2023, 25, 1771
DOI: 10.1021/acs.orglett.3c00518

Recent developments in C–H functionalization of azauracils

Juanjuan Wu, Leilei Wang and Kelu Yan

Tetrahedron, 2026, 193, 135128
DOI: 10.1016/j.tet.2025.135128

Mechanistic Insight into the Ni-Catalyzed Kumada Cross-Coupling: Alkylmagnesium Halide Promotes C–F Bond Activation and Electron-Deficient Metal Center Slows Down β-H Elimination

Yuanyuan Li and Jun Zhu

J. Org. Chem., 2022, 87, 8902
DOI: 10.1021/acs.joc.2c00586

Arylation Reactions in the Synthesis of Biologically Important 2,5-Diaryl-1,3,4-Oxadiazoles

Monika Olesiejuk and Agnieszka Kudelko

Applied Sciences, 2022, 12, 7806
DOI: 10.3390/app12157806

Template Synthesis to Solve the Unreachable Ortho C–H Functionalization Reaction of Aryl Iodide

Bo-Sheng Zhang, Wan-Yuan Jia, Yi-Ming Wang, João C. A. Oliveira, Svenja Warratz, Ze-Qiang Zhang, Xue-Ya Gou, Yong-Min Liang, Xi-Cun Wang, Zheng-Jun Quan and Lutz Ackermann

J. Org. Chem., 2023, 88, 16539
DOI: 10.1021/acs.joc.3c02014

Defluorinative Asymmetric Allylic Alkylations

Paula Rodríguez, Jordi Duran, Martí Gisbert and Xavier Companyó

Synlett, 2024, 35, 1613
DOI: 10.1055/a-2211-6538

Optimal exploitation of supported heterogenized Pd nanoparticles for C-C cross-coupling reactions

Abhay Srivastava, Harsimar Kaur, Harsh Pahuja, T.M. Rangarajan, Rajender S. Varma and Sharda Pasricha

Coordination Chemistry Reviews, 2024, 507, 215763
DOI: 10.1016/j.ccr.2024.215763

Preparation of palygorskite grafted fluorescent covalent organic framework and the application in C C coupling reactions

Yun Lei, Xinyu Bai, Shuo Tian, Xin Wang, Huiying Zhan, Haixiong Shi, Penghui Zhang, Shuxia Zhang, Jixia Wang, Xuan Yao, Quanlu Yang and Shang Wu

Tetrahedron Letters, 2025, 165-166, 155641
DOI: 10.1016/j.tetlet.2025.155641

Gold‐Catalyzed Heck and Suzuki‐Type Reactions: Challenges and Recent Advances

Jiawen Wu, Wenqian Du, Lizhu Zhang, Gang Li and Zhonghua Xia

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400793

Radical Cascade Cyclization of N-(o-Cyanobiaryl)acrylamides with Sulfonium Salts via Synergetic Photoredox and Copper Catalysis

Xin-Qian Liu, Hui Chen, Jian-Hong Fan, Ke-Wen Tang, Long-Jin Zhong and Yu Liu

Org. Lett., 2024, 26, 7650
DOI: 10.1021/acs.orglett.4c02759

Palladium-Catalyzed Defluorinative Alkylation of gem-Difluoroalkenes with Cyclopropanols: Stereoselective Synthesis of γ-Fluorinated γ,δ-Unsaturated Ketones

Lingyu Kong, Wenqing Ti, Aijun Lin, Hequan Yao, Yue Huang and Xuanyi Li

Org. Lett., 2024, 26, 3591
DOI: 10.1021/acs.orglett.4c01045

Direct Stannylation and Silylation of Arylmethanols by Palladium Catalysis

Guanglu Yue, Qianyi Liu, Jingyao Wei, Yanqiong Pi, Di Qiu and Fanyang Mo

J. Org. Chem., 2023, 88, 2735
DOI: 10.1021/acs.joc.2c02265

Recent Advances of C−S Coupling Reaction of (Hetero)Arenes by C−H Functionalization

Lei‐Yang Zhang, Nai‐Xing Wang, Dumitra Lucan, Julia Nastasi and Yalan Xing

The Chemical Record, 2024, 24
DOI: 10.1002/tcr.202400177

Chroman‐4‐one‐Based Amino Bidentate Ligand: An Efficient Ligand for Suzuki‐Miyaura and Mizoroki‐Heck Coupling Reactions in Aqueous Medium

Danish Khan and Iram Parveen

Eur J Org Chem, 2021, 2021, 4946
DOI: 10.1002/ejoc.202100866

Transition metal nanoparticles as nanocatalysts for Suzuki, Heck and Sonogashira cross-coupling reactions

Muhammad Ashraf, Muhammad Sohail Ahmad, Yusuke Inomata, Nisar Ullah, Muhammad Nawaz Tahir and Tetsuya Kida

Coordination Chemistry Reviews, 2023, 476, 214928
DOI: 10.1016/j.ccr.2022.214928

[CuI(PPh3)3]‐Mediated Arylation of 1,2,3‐Triazoles

Steven Lal, Jialei Qian, Raul Pacheco‐Muino, Vera Kleene, Matthew J. Foulkes and Silvia Díez‐González

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202500111

Nickel-catalyzed Suzuki cross-coupling reaction of alkyl triaryl phosphonium salts

Meiqi Zhu, Wen Yu, Qin Zhong, Benqiang Cui, Changsheng Cao and Yanhui Shi

Tetrahedron, 2023, 135, 133321
DOI: 10.1016/j.tet.2023.133321

Iron-Mediated One-Pot Dehydroxylative Cross-Electrophile Coupling of Alcohol with Disulfide for Thioether Synthesis by Using TCT as a Hydroxyl-Activating Agent

Meng-Ke Xu, Xuan-Qi Zhang, Yong-Qing Xu, Xue-Qiang Chu, Hao Xu, Xiaocong Zhou, Weidong Rao and Zhi-Liang Shen

Org. Lett., 2025, 27, 5152
DOI: 10.1021/acs.orglett.5c01308

Enabling the Use of Alkyl Thianthrenium Salts in Cross‐Coupling Reactions by Copper Catalysis

Cheng Chen, Minyan Wang, Hongjian Lu, Binlin Zhao and Zhuangzhi Shi

Angew Chem Int Ed, 2021, 60, 21756
DOI: 10.1002/anie.202109723

Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C–S Bond Activation

Qian-Qian Fu, Yuan Liang, Xiao-Xiao Sun, Xue-Qiang Chu, Hao Xu, Xiaocong Zhou, Weidong Rao and Zhi-Liang Shen

Org. Lett., 2024, 26, 8577
DOI: 10.1021/acs.orglett.4c03208

HP(O)Ph2-Mediated Hydrodefluorination of Polyfluoro(hetero)arenes

Xue-Ying Huang, Xian-Xian Mao, Chenshu Dai, Ming-Yang Gu, Danhua Ge, Zhi-Liang Shen, Kai Guo, Chao-Jun Li and Xue-Qiang Chu

JACS Au, 2026, 6, 1602
DOI: 10.1021/jacsau.5c01460

Nickel‐Catalyzed Stereo‐ and Enantioselective Cross‐Coupling of gem‐Difluoroalkenes with Carbon Electrophiles by C−F Bond Activation

Ziqi Zhu, Lin Lin, Jieshuai Xiao and Zhuangzhi Shi

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202113209

Nickel-Catalyzed Decarbonylative Reductive Alkylation of Aroyl Fluorides with Alkyl Bromides

Qiang Chen, Jingwen You, Tian Tian, Zhenyao Li, Myuto Kashihara, Hiroki Mori and Yasushi Nishihara

Org. Lett., 2022, 24, 9259
DOI: 10.1021/acs.orglett.2c03823

Transamidation and Decarbonylation of N-Phthaloyl-Amino Acid Amides Enabled by Palladium-Catalyzed Selective C–N Bond Cleavage

Hao-Yu Zhang, Xuan-Wen Tao, Li-Na Yi, Zhi-Gang Zhao and Qiang Yang

J. Org. Chem., 2022, 87, 231
DOI: 10.1021/acs.joc.1c02245

Ru(II)- or Rh(III)-Catalyzed Annulation of Aromatic/Vinylic Acids with AlkylidenecyclopropanesviaC–H Activation

Balu Ramesh and Masilamani Jeganmohan

J. Org. Chem., 2022, 87, 5668
DOI: 10.1021/acs.joc.1c03141

Nickel-catalyzed cross-electrophile coupling of unactivated (hetero)aryl sulfone with aryl bromide

Wen-Xin Li, Bo-Jie Huo, Jie-Ying Huang, Weidong Rao, Hao Xu, Xiaocong Zhou and Zhi-Liang Shen

Journal of Catalysis, 2024, 430, 115359
DOI: 10.1016/j.jcat.2024.115359

Nickel‐Catalyzed Cross‐Electrophile Coupling of Aryl Phosphates with Aryl Bromides

Jing‐Ao Ren, Xue Chen, Chao Gui, Chengping Miao, Xue‐Qiang Chu, Hao Xu, Xiaocong Zhou, Mengtao Ma and Zhi‐Liang Shen

Adv Synth Catal, 2023, 365, 2511
DOI: 10.1002/adsc.202300663

Microenvironment modulation of cuprous cluster enables inert aryl chlorides activation in single-molecule metallaphotoredox amination

Guo-Jin Zha, Wei Ji, Zheng-Hang Qi, Wen-Jie Qiu, Ai-Min Li, Dun-Ru Zhu and Su Jing

Journal of Catalysis, 2022, 405, 313
DOI: 10.1016/j.jcat.2021.12.007

Unveiling the Synthetic Potential of Conjugated Organic Molecule as Efficient Photo-catalytic Trifluoromethylation and Photo-cocatalytic C–N Coupling Reaction

Yumin Pan, Tingting Xie, Jiming Peng, Cuihui Cao and Bi-Qun Zou

Catal Lett, 2025, 155
DOI: 10.1007/s10562-024-04900-x

Modular Synthesis of Furans with Four Nonidentical Substituents by Aqueous Defluorinative Reaction of Trifluoromethyl Enones with Two Nucleophiles

Xue-Ying Huang, Shu-Ji Gao, Danhua Ge, Mengtao Ma, Zhi-Liang Shen and Xue-Qiang Chu

Org. Lett., 2025, 27, 462
DOI: 10.1021/acs.orglett.4c04488

Nickel‐Catalyzed Csp2−OMe Functionalization for Chemoselective Aromatic Homologation En Route to Nanographenes

Lorena Capdevila, Judith Sala, Lutz Ackermann and Xavi Ribas

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202200625

Iso‐Pentadienyl Carbonate as a Five Carbon Synthon in Manganese(I)‐Catalyzed Selective Linear 1,3‐Dienylation

Shubham Singh, Athira Parammal, Manoj Kumar, Joe Sam X and Parthasarathi Subramanian

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202301632

Hydroxylation of Aryl Sulfonium Salts for Phenol Synthesis under Mild Reaction Conditions

Xuan-Bo Hu, Qian-Qian Fu, Xue-Ying Huang, Xue-Qiang Chu, Zhi-Liang Shen, Chengping Miao and Weiyi Chen

Molecules, 2024, 29, 831
DOI: 10.3390/molecules29040831

Direct C(sp3)–H Polyfluoroarylation: Access to Polyfluoroaryl Amino Acids via Rh-Catalyzed Selective C–F Bond Cleavage

Xuan-Wen Tao, Li-Na Yi, Meng-Yi Huang, Yun Fu and Qiang Yang

J. Org. Chem., 2022, 87, 14476
DOI: 10.1021/acs.joc.2c01906

Nickel-Catalyzed Enantio- and Diastereoselective Synthesis of Fluorine-Containing Vicinal Stereogenic Centers

Uttam Dhawa, Lara Lavrencic and Xile Hu

ACS Cent. Sci., 2024, 10, 1657
DOI: 10.1021/acscentsci.4c00819

A study of the reactivity of 2,4-diphenylfuran

Alexander A. Fedorov, Danil A. Myasnikov and Maxim G. Uchuskin

Chem Heterocycl Comp, 2023, 59, 713
DOI: 10.1007/s10593-023-03259-y

Photo‐ and Cerium‐Mediated C─C Bond Cleavage for the Deconstructive Diversification of Cyclic Acids

Yan Xu, Jianjie Wang, Qian Zhang, Xinyao Hu, Chun Lv, Heng Yang, Bin Sun and Can Jin

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202500561

Photo‐ and Rh‐Promoted Cross‐Coupling Reactions of α‐Hydroxy Aryl Ketones via Cleavage of Carbon–Carbon σ‐Bonds

Atsuya Shimizu, Haruka Tan and Jun Takaya

ChemistrySelect, 2026, 11
DOI: 10.1002/slct.72585

Nickel-Catalyzed Reductive Amidation of Aryl Fluorosulfates with Isocyanates: Synthesis of Amides via C–O Bond Cleavage

Gan-Qi Qin, Jiao Wang, Xu-Rong Cao, Xue-Qiang Chu, Xiaocong Zhou, Weidong Rao, Li-Xin Zhai, Chengping Miao and Zhi-Liang Shen

J. Org. Chem., 2024, 89, 13735
DOI: 10.1021/acs.joc.4c01399

Phosphine-Catalyzed Dearomative [3 + 2] Cycloaddition of Benzoxazoles with a Cyclopropenone

Xingben Wang, Congjun Yu, Iuliana L. Atodiresei and Frederic W. Patureau

Org. Lett., 2022, 24, 1127
DOI: 10.1021/acs.orglett.1c04045

A Highly Efficient Cross‐Coupling Mode via the Release of Small Molecules: Transition Metal‐Catalyzed Unimolecular Fragment Coupling (UFC)

Tian Tian, Shuhei Uei, Zhiping Li and Yasushi Nishihara

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202401190

Nickel-Catalyzed Stereoselective Cascade C–F Functionalizations of gem-Difluoroalkenes

Xiaowei Li, Yuxiu Li, Zemin Wang, Wenlong Shan, Ruihua Liu, Cong Shi, Hongyun Qin, Leifeng Yuan, Xiangqian Li and Dayong Shi

ACS Catal., 2023, 13, 2135
DOI: 10.1021/acscatal.3c00047

RadicalRetro: A Deep Learning-Based Retrosynthesis Model for Radical Reactions

Jiangcheng Xu, Jun Dong, Kui Du, Wenwen Liu, Jiehai Peng and Wenbo Yu

Processes, 2025, 13, 1792
DOI: 10.3390/pr13061792

Nickel‐Catalyzed Stereo‐ and Enantioselective Cross‐Coupling of gem‐Difluoroalkenes with Carbon Electrophiles by C−F Bond Activation

Ziqi Zhu, Lin Lin, Jieshuai Xiao and Zhuangzhi Shi

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202113209

Rosa Indica flower petal anthocyanin mediated biogenic synthesis of PdNPs: Catalyst intended for the Suzuki-Miyaura reactions

Rahul A. Kalel, Prakash B. Rathod, Ankita S. Jadhav and Dipalee D. Malkhede

Polyhedron, 2024, 249, 116784
DOI: 10.1016/j.poly.2023.116784

Versatile deacylative cross-coupling of aromatic ketones

Hikaru Nakahara, Ryota Isshiki, Masayuki Kubo, Keiichiro Iizumi, Kei Muto and Junichiro Yamaguchi

Chem, 2024, 10, 2916
DOI: 10.1016/j.chempr.2024.07.002

Visible-Light Photoredox-Catalyzed Carboxylation of Benzylic C(sp3)–O Bonds in Ethers with CO2

Jing-Wei Yang, Chuan-Kun Ran, Wen-Jing Zhu, Yi Jiang, Si-Shun Yan, Jian-Heng Ye and Da-Gang Yu

J. Org. Chem., 2025, 90, 8406
DOI: 10.1021/acs.joc.5c01091

Silica-supported Schiff-based palladium nanocatalyzed cross-coupling reactions and its applications in the synthesis of antiplatelet and fungicidal

Jun Li, Gaoliang Wang, Honglei Yuan, Kun Feng and Xianke Sun

Arabian Journal of Chemistry, 2023, 16, 105203
DOI: 10.1016/j.arabjc.2023.105203

Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays

Thomas Gerstberger, Helmut Berger, Frank H. Büttner, Michael Gmachl, Dirk Kessler, Manfred Koegl, Simon Lucas, Laetitia J. Martin, Moriz Mayer, Darryl B. McConnell, Sophie Mitzner, Guido Scholz, Matthias Treu, Bernhard Wolkerstorfer, Stephan Zahn, Krzysztof M. Zak, Philipp A. Jaeger and Peter Ettmayer

J. Med. Chem., 2024, 67, 11701
DOI: 10.1021/acs.jmedchem.3c02381

C−P Bond Formation by Nickel or Cobalt Catalyzed Coupling Reactions

Anju Modi, Corinne Gosmini and Audrey Auffrant

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202401780

Nickel-catalyzed cross-coupling of 2-fluorobenzofurans with arylboronic acids via aromatic C–F bond activation

Takeshi Fujita, Haruna Yabuki, Ryutaro Morioka, Kohei Fuchibe and Junji Ichikawa

Beilstein J. Org. Chem., 2025, 21, 146
DOI: 10.3762/bjoc.21.8

Visible Light Catalyzed Reductive Cross‐Coupling of α‐CF3‐alkyl Bromide and Alkynyl Bromide†

Yiqiang Tian, Yi Li and Chun Zhang

Chin. J. Chem., 2024, 42, 2479
DOI: 10.1002/cjoc.202400402

Na2S·9H2O Enabled Defluorodisulfuration and Hydrodefluorination of Perfluorobutyl Tetralones: Synthesis of Trifluoromethyl 1,2-Dithioles

Zi-Lun Yu, Man-Hang Feng, Peng-Yuan Zhang, Hao Xu, Danhua Ge, Mengtao Ma, Zhi-Liang Shen and Xue-Qiang Chu

Org. Lett., 2023, 25, 4388
DOI: 10.1021/acs.orglett.3c01573

Exploring Carbon-based Materials as a tailored platform for Suzuki–Miyaura Coupling Reaction: A Review

Sobia Jabeen, Yaxi Li, Xin Wu, Yuanyuan Cheng, Yunliang Liu, Jingwen Yu, Naiyun Liu, Jun Huang and Haitao Li

Coordination Chemistry Reviews, 2025, 524, 216323
DOI: 10.1016/j.ccr.2024.216323

Carbodefluorination of fluoroalkyl ketones via a carbene-initiated rearrangement strategy

Linxuan Li, Xinyu Zhang, Yongquan Ning, Xiaolong Zhang, Binbin Liu, Zhansong Zhang, Paramasivam Sivaguru, Giuseppe Zanoni, Shuang Li, Edward A. Anderson and Xihe Bi

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-31976-z

Palladium-Catalyzed α-Arylation of Nitroalkanes with Aryl Fluorosulfonates for Convenient Access to α-Arylated Nitroalkanes

Chen-Long Zhu, Fei Zhao, Yuan-Yuan Wang, Xue-Qiang Chu, Hao Xu, Chengping Miao, Weidong Rao and Zhi-Liang Shen

J. Org. Chem., 2025, 90, 12199
DOI: 10.1021/acs.joc.5c01502

Visible‐Light‐Induced ArC(sp3)−F Bond Activation in Aqueous Media: From DFT Study to Molecular Design

Cefei Zhang, Sitong Li, Lijun Deng, Jinmeng Yan, Zhishan Su, Zhipeng Yu and Changwei Hu

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202403729

Nickel-Catalyzed Direct Cross-Coupling of Aryl Fluorosulfates with Aryl Bromides

Jin-He Na, Xiang Liu, Jia-Wen Jing, Jing Wang, Xue-Qiang Chu, Mengtao Ma, Hao Xu, Xiaocong Zhou and Zhi-Liang Shen

Org. Lett., 2023, 25, 2318
DOI: 10.1021/acs.orglett.3c00674

Nickel-catalyzed reductive cross-coupling of polyfluoroarenes with alkyl electrophiles by site-selective C–F bond activation

Longlong Xi, Liting Du and Zhuangzhi Shi

Chinese Chemical Letters, 2022, 33, 4287
DOI: 10.1016/j.cclet.2022.01.077

Ligand‐Controlled Palladium‐Catalyzed Regiodivergent Defluorinative Allylation of gem‐Difluorocyclopropanes via σ‐Bond Activation

Lei Wu, Minyan Wang, Yong Liang and Zhuangzhi Shi

Chin. J. Chem., 2022, 40, 2345
DOI: 10.1002/cjoc.202200307

Selective Electroreductive Cross-Coupling of N-Heteroarenes and Aryl Carboxylic Derivatives

Xinyu Chen, Maorui Wang, Huanfeng Jiang, Pierre. H. Dixneuf and Min Zhang

J. Am. Chem. Soc., 2025
DOI: 10.1021/jacs.5c16945

Cobalt/Rhodium-Catalyzed Diversified Amidation of Benzocyclobutenols via C–C Cleavage under Catalyst and Condition Control

Xingwei Li, Runze Zhang, Zisong Qi, Junwei Li and Lingheng Kong

Org. Lett., 2023, 25, 5078
DOI: 10.1021/acs.orglett.3c01788

Nickel-catalyzed cross-electrophile couplings of aryl fluorosulfates with vinyl chlorosilanes

Jin-He Na, Hong-Jian Du, Jia-Wen Jing, Xue-Qiang Chu, Xiao-Chun Hang, Zhi-Liang Shen, Xiaocong Zhou and Haiqing Luo

Journal of Catalysis, 2024, 437, 115636
DOI: 10.1016/j.jcat.2024.115636

Molybdenum-doped carbon nitride as an efficient heterogeneous catalyst for direct amination of nitroarenes with arylboronic acids

Wen-Jing Li, Jun-Bo Wang, Yu-Heng Liu, Mo Zhang and Zhan-Hui Zhang

Chinese Chemical Letters, 2025, 36, 110001
DOI: 10.1016/j.cclet.2024.110001

Synthesis of Fluorinated Compounds by Nickel-Catalyzed Defluorinative Cross-Coupling Reactions

Kuai Wang and Wangqing Kong

ACS Catal., 2023, 13, 12238
DOI: 10.1021/acscatal.3c02993

Transition‐Metal‐Free Regioselective C−H Arylation of Heteroarenes

Shubhanjali Choudhary, Tanisha Yadav, Jarsha Jaleel, Pragati Sharma, Ritika Jaryal, Shubahnakar Bose and Rakesh Kumar

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400891

Nickel-Catalyzed Desulfurative Cross-Coupling of Aryl Iodides with Heteroaromatic Thioethers via C–S Bond Cleavage

Pingliang Zhu, Yu Zhao, Shaowen Ling, Baolong Xu, Hui Liu, Xinjin Li and Feng-Gang Sun

J. Org. Chem., 2024, 89, 12001
DOI: 10.1021/acs.joc.4c00678

Divergent Transformations of Aromatic Esters: Decarbonylative Coupling, Ester Dance, Aryl Exchange, and Deoxygenative Coupling

Masayuki Kubo and Junichiro Yamaguchi

Acc. Chem. Res., 2024, 57, 1747
DOI: 10.1021/acs.accounts.4c00233

Nickel-Catalyzed Reductive Borylation of Enaminones via C(sp2)–N Bond Cleavage

Xiaoning Li, Zunsheng Chen, Yan Liu, Nianhua Luo, Weiming Chen, Chenfu Liu, Fuchao Yu and Jiuzhong Huang

J. Org. Chem., 2022, 87, 10349
DOI: 10.1021/acs.joc.2c00096

Synthesis and application of Pd-Ni bimetallic nanoparticles supported on nitrogen-doped carbon materials

Yuxin Sun, Yanjie Jiang, Yao Liu, Zhangpei Chen, Xiaoxu Xu and Jianshe Hu

Applied Surface Science, 2025, 705, 163544
DOI: 10.1016/j.apsusc.2025.163544

Organic charge-transfer complex induces chemoselective decarboxylation to aryl radicals for general functionalization

Chun-Hong Hu, Yueqian Sang, Ya-Wei Yang, Wen-Wen Li, Hui-Lin Wang, ZiYing Zhang, Chen Ye, Li-Zhu Wu, Xiao-Song Xue and Yang Li

Chem, 2023, 9, 2997
DOI: 10.1016/j.chempr.2023.06.022

A Practically Unified Electrochemical Strategy for Ni-Catalyzed Decarboxylative Cross-Coupling of Aryl Trimethylammonium Salts

Xianqiang Kong, Yiyi Chen, Xiaohui Chen, Zheng-Xuan Lu, Wei Wang, Shao-Fei Ni and Zhong-Yan Cao

Org. Lett., 2022, 24, 2137
DOI: 10.1021/acs.orglett.2c00408

Ru(II)-Catalyzed [3 + 3] Annulation of Benzamides with Iodonium Ylides via Redox-Neutral C–H Bond Functionalization

Shanmugarajan Jothi Murugan, Suresh Kumar Yadav and Masilamani Jeganmohan

J. Org. Chem., 2025, 90, 10662
DOI: 10.1021/acs.joc.5c00979

Magnetic nanoparticles β-Cyclodextrin-supported nickel catalyst (Ni-MNPCD): Efficient, sustainable and reusable catalyst for ligand-free and phenol-based C C and C N coupling reactions

Maryam Tukhani, Abdolreza Hajipour and Alireza Najafi Chermahini

Carbohydrate Polymers, 2026, 373, 124603
DOI: 10.1016/j.carbpol.2025.124603

Heterolytic bond dissociation energy related to C−F activation in nickel-catalyzed cross-coupling of phenylmagnesium chloride with fluoroarenes

Hongli Wu, Junjie Tai, Jialun Xu, Shuo-Qing Zhang, Yuanbin She and Yun-Fang Yang

Journal of Organometallic Chemistry, 2025, 1035, 123674
DOI: 10.1016/j.jorganchem.2025.123674

Efficient Decarboxylative/Defluorinative Alkylation for the Synthesis of gem‐Difluoroalkenes through an SN2’‐Type Route

Wei‐Long Xing, Jia‐Xin Wang, Ming‐Chen Fu and Yao Fu

Chin. J. Chem., 2022, 40, 323
DOI: 10.1002/cjoc.202100709

Nickel- or Palladium-Catalyzed Decarbonylative Transformations of Acyl Halides

Tian Tian and Yasushi Nishihara

J. Synth. Org. Chem. Jpn., 2025, 83, 746
DOI: 10.5059/yukigoseikyokaishi.83.746

Carbonylative transformation of aryl halides and strong bonds via cheap metal catalysts and sustainable technologies

Maolin Yang, Yukun Liu, Xin Qi, Yanhua Zhao and Xiao-Feng Wu

Green Synthesis and Catalysis, 2024, 5, 211
DOI: 10.1016/j.gresc.2024.04.008

Palladium–Catalyzed α‐Arylation of Sulfoxonium Ylides with Aryl Thianthrenium Salts via C−S and C−H Bond Activation

Qing‐Dong Wang, Xue Chen, Yuan‐Shuai Wu, Chengping Miao, Jin‐Ming Yang and Zhi‐Liang Shen

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202401873

Cobalt(III)-Catalyzed Chemo- and Regioselective [4 + 2]-Annulation of Aromatic Sulfoxonium Ylides with 1,3-Diynes

Suresh Kumar Yadav, Balu Ramesh and Masilamani Jeganmohan

J. Org. Chem., 2022, 87, 4134
DOI: 10.1021/acs.joc.1c02967

Recent Progress on Transition-Metal-Mediated Reductive C(sp3)–O Bond Radical Addition and Coupling Reactions

Li Cheng, Quan Lin, Yunrong Chen and Hegui Gong

Synthesis, 2022, 54, 4426
DOI: 10.1055/a-1848-3005

Photoinduced EDA Complexes Enabled C(sp2)–OMe Bond Cleavage and Cyanation of Electron-Rich Arenes

Jun Zhou, Sijia Zhang, Wenjie Liu, Jiaxin Yang, Xi Du, Siping Wei, Xia Zhou, Anping Luo and Bowen Lei

Org. Lett., 2025, 27, 6800
DOI: 10.1021/acs.orglett.5c01967

Quinoline as an Intramolecular Hydride Shuttle in the Deoxygenative Coupling Reaction of Alcohol and the Inert Methyl C(sp3)–H Bond

Hui-Yun Wang, Zhen-Yuan Liu, Long-Xue Wang, Da-Ying Shao, Feng-Ying Dong, Yao-Bin Shen, Bin Qiu, Jian Xiao and Xiao-De An

J. Org. Chem., 2024, 89, 18406
DOI: 10.1021/acs.joc.4c02269

Bifunctional Photoactive Chiral Ligands Enable Visible‐Light‐Induced Nickel‐Catalyzed Enantioselective C−O Coupling

Junjie Xue, Lei Su, Weiwei Fang, Shen Gao, Qingshu Zheng and Jiawang Liu

Angewandte Chemie, 2026, 138
DOI: 10.1002/ange.202523823

Nickel‐Catalyzed Cross‐Electrophile Coupling of Triazine Esters with Aryl Bromides

Xiang Liu, Cai‐Yu He, Hao‐Nan Yin, Chengping Miao, Xue‐Qiang Chu, Weidong Rao, Hao Xu, Xiaocong Zhou and Zhi‐Liang Shen

Chin. J. Chem., 2023, 41, 3539
DOI: 10.1002/cjoc.202300399