Issue 39, 2021

Emerging nanomaterials applied for tackling the COVID-19 cytokine storm

Abstract

During the global outbreak of coronavirus disease 2019 (COVID-19), a hyperinflammatory state called the cytokine storm was recognized as a major contributor to multiple organ failure and mortality. However, to date, the diagnosis and treatment of the cytokine storm remain major challenges for the clinical prognosis of COVID-19. In this review, we outline various nanomaterial-based strategies for preventing the COVID-19 cytokine storm. We highlight the contribution of nanomaterials to directly inhibit cytokine release. We then discuss how nanomaterials can be used to deliver anti-inflammatory drugs to calm the cytokine storm. Nanomaterials also play crucial roles in diagnostics. Nanomaterial-based biosensors with improved sensitivity and specificity can be used to detect cytokines. In summary, emerging nanomaterials offer platforms and tools for the detection and treatment of the COVID-19 cytokine storm and future pandemic.

Graphical abstract: Emerging nanomaterials applied for tackling the COVID-19 cytokine storm

Article information

Article type
Review Article
Submitted
29 jun. 2021
Accepted
19 ago. 2021
First published
16 sep. 2021

J. Mater. Chem. B, 2021,9, 8185-8201

Emerging nanomaterials applied for tackling the COVID-19 cytokine storm

X. Yang, J. You, Y. Wei, H. Li, L. Gao, Q. Guo, Y. Huang, C. Gong and C. Yi, J. Mater. Chem. B, 2021, 9, 8185 DOI: 10.1039/D1TB01446C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements