Issue 24, 2019

Red-emitting pyrene–benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect

Abstract

A series of pyrene–benzothiazolium probes were synthesized. By replacing the pyridinium with a benzothiazolium unit, the selectivity of pyrene-derivatives is found to switch from nuclear to cellular lysosomes. New probes do not require proton participation and exhibit high biocompatibility and long-term imaging ability.

Graphical abstract: Red-emitting pyrene–benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect

Supplementary files

Article information

Article type
Communication
Submitted
05 feb. 2019
Accepted
25 feb. 2019
First published
04 mar. 2019

Chem. Commun., 2019,55, 3469-3472

Red-emitting pyrene–benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect

C. S. Abeywickrama, K. J. Wijesinghe, R. V. Stahelin and Y. Pang, Chem. Commun., 2019, 55, 3469 DOI: 10.1039/C9CC01068H

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