Issue 2, 2017

Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata

Abstract

The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminase from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed into the corresponding amines in good to excellent yields. The process was implemented with an integrated in-line purification step for the recovery of the pure amines.

Graphical abstract: Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata

Supplementary files

Article information

Article type
Communication
Submitted
29 jun. 2016
Accepted
03 ago. 2016
First published
03 ago. 2016

Green Chem., 2017,19, 372-375

Author version available

Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata

M. Planchestainer, M. L. Contente, J. Cassidy, F. Molinari, L. Tamborini and F. Paradisi, Green Chem., 2017, 19, 372 DOI: 10.1039/C6GC01780K

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