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Themed collection Recent Open Access Articles

54 items
Open Access Paper

Nanoparticle-supported polymer brushes for temperature-regulated glycoprotein separation: investigation of structure–function relationship

Nanoparticle-supported polymer brushes enable temperature-regulated protein binding and release.

Graphical abstract: Nanoparticle-supported polymer brushes for temperature-regulated glycoprotein separation: investigation of structure–function relationship
From the themed collection: Recent Open Access Articles
Open Access Review Article

Amorphous polyphosphate, a smart bioinspired nano-/bio-material for bone and cartilage regeneration: towards a new paradigm in tissue engineering

Physiological amorphous polyphosphate nano/micro-particles, injectable and implantable, attract and stimulate MSCs into implants for tissue regeneration.

Graphical abstract: Amorphous polyphosphate, a smart bioinspired nano-/bio-material for bone and cartilage regeneration: towards a new paradigm in tissue engineering
From the themed collection: Recent Review Articles
Open Access Paper

Biodegradable nitric oxide precursor-loaded micro- and nanoparticles for the treatment of Staphylococcus aureus biofilms

Bacteria in biofilms are more difficult to eradicate than planktonic bacteria and result in treatment challenges for many chronic infectious diseases.

Graphical abstract: Biodegradable nitric oxide precursor-loaded micro- and nanoparticles for the treatment of Staphylococcus aureus biofilms
From the themed collection: Recent Open Access Articles
Open Access Paper

Exploiting the protein corona around gold nanorods for low-dose combined photothermal and photodynamic therapy

We load Ce6 onto NRs using its protein corona, deliver them to cells before performing laser irradiation for simultaneous PTT and PDT with greatly enhanced therapeutic efficacy.

Graphical abstract: Exploiting the protein corona around gold nanorods for low-dose combined photothermal and photodynamic therapy
From the themed collection: Recent Open Access Articles
Open Access Paper

Non-invasive characterization of hybrid gelatin:poly-L-lactide electrospun scaffolds using second harmonic generation and multiphoton imaging

In this work we generated hybrid gelatin:poly-L-lactide electrospun scaffolds and implemented non-invasive methods to characterize them.

Graphical abstract: Non-invasive characterization of hybrid gelatin:poly-l-lactide electrospun scaffolds using second harmonic generation and multiphoton imaging
From the themed collection: Recent Open Access Articles
Open Access Paper

Growth behaviour of silica/carbonate nanocrystalline composites of calcite and aragonite

The precipitation of calcium carbonate into alkaline silica gel produces concomitant polymorphic precipitation of aragonite with biomorphic morphology and calcite crystalline dendrites.

Graphical abstract: Growth behaviour of silica/carbonate nanocrystalline composites of calcite and aragonite
From the themed collection: Recent Open Access Articles
Open Access Paper

Low-fouling, mixed-charge poly-L-lysine polymers with anionic oligopeptide side-chains

A mixed-charge polymer, with anionic oligopeptide moieties attached to a cationic poly-L-lysine backbone, provides antifouling surfaces for human plasma samples.

Graphical abstract: Low-fouling, mixed-charge poly-l-lysine polymers with anionic oligopeptide side-chains
From the themed collection: Recent Open Access Articles
Open Access Paper

Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes

The introduction of a small amount of the organic cosolvent dimethyl sulfoxide leads to a remarkable improvement of the photophysical properties of the complex between hypericin and lactoglobulin.

Graphical abstract: Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes
From the themed collection: Recent Open Access Articles
Open Access Paper

On the subtle tuneability of cellulose hydrogels: implications for binding of biomolecules demonstrated for CBM 1

Choice of molecular probe for determining porosity, surface area, or binding in never-dried cellulose hydrogels is critical to discern differences in structure.

Graphical abstract: On the subtle tuneability of cellulose hydrogels: implications for binding of biomolecules demonstrated for CBM 1
From the themed collection: Recent Open Access Articles
Open Access Communication

Stable DHLA–PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging

Stability, biocompatibility and near-infrared photoluminescence of PbS nanocrystals capped with PEG-based ligands open up realistic prospects for non-invasive bioimaging applications.

Graphical abstract: Stable DHLA–PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging
From the themed collection: Recent Open Access Articles
Open Access Paper

Switchable presentation of cytokines on electroactive polypyrrole surfaces for hematopoietic stem and progenitor cells

Redox potential-dependent switching of immobilized interleukin-3 presentation towards hematopoietic progenitor cells using electroactive polypyrrole surfaces affects cell viability.

Graphical abstract: Switchable presentation of cytokines on electroactive polypyrrole surfaces for hematopoietic stem and progenitor cells
From the themed collection: Recent Open Access Articles
Open Access Paper

Antibody-modified hydroxyapatite surfaces for the efficient capture of bladder cancer cells in a patient's urine without recourse to any sample pre-treatment

In this study, we describe a sensitive protocol for the detection of bladder cancer cells in a patient's urine without pre-treatment of the urine sample using antibody-modified hydroxyapatite (HAp) micro/nanostructured surfaces converted from natural seashells under mild biomineralization conditions.

Graphical abstract: Antibody-modified hydroxyapatite surfaces for the efficient capture of bladder cancer cells in a patient's urine without recourse to any sample pre-treatment
From the themed collection: Recent Open Access Articles
Open Access Paper

Reactive oxygen species mediated theranostics using a Fenton reaction activable lipo-polymersome

A succinic peroxide-filled Fenton reaction activable Pt/Fe3O4@SP-PLGA lipo-polymersome displays ROS mediated chemodynamic therapy (CDT).

Graphical abstract: Reactive oxygen species mediated theranostics using a Fenton reaction activable lipo-polymersome
From the themed collection: Recent Open Access Articles
Open Access Paper

Effective co-delivery of nutlin-3a and p53 genes via core–shell microparticles for disruption of MDM2–p53 interaction and reactivation of p53 in hepatocellular carcinoma

Using core–shell microparticles encapsulating p53/β-CD-g-CS NPs and nutlin-3a effectively suppressed p53–MDM2 interaction and restored p53 apoptotic activity in cancer cells.

Graphical abstract: Effective co-delivery of nutlin-3a and p53 genes via core–shell microparticles for disruption of MDM2–p53 interaction and reactivation of p53 in hepatocellular carcinoma
From the themed collection: Recent Open Access Articles
Open Access Paper

Composite vector formulation for multiple siRNA delivery as a host targeting antiviral in a cell culture model of hepatitis C virus (HCV) infection

RNA interference-based gene therapies are promising tool to treat chronic viral infections. We design composite nanoparticle by the LbL technique to deliver sequentially siRNA against host targeting agents. They proved to be efficient in controlling HCV replication with up to 90% reduction over 10 days.

Graphical abstract: Composite vector formulation for multiple siRNA delivery as a host targeting antiviral in a cell culture model of hepatitis C virus (HCV) infection
From the themed collection: Recent Open Access Articles
Open Access Paper

Hierarchically designed hybrid nanoparticles for combinational photochemotherapy against a pancreatic cancer cell line

Hierarchical formulation of hybrid nanoparticles that consist of aggregated gold nanoparticles impregnated into a gemcitabine–polymer conjugate matrix for photochemotherapy of pancreatic cancer.

Graphical abstract: Hierarchically designed hybrid nanoparticles for combinational photochemotherapy against a pancreatic cancer cell line
From the themed collection: Recent Open Access Articles
Open Access Paper

A one-pot synthesis of water soluble highly fluorescent silica nanoparticles

We report a one-pot synthesis of water dispersible fluorescent silica nanoparticles (NPs) functionalized with terminal amine groups, starting from silicon tetrabromide (SiBr4) and aminopropyltriethoxy silane (APTES).

Graphical abstract: A one-pot synthesis of water soluble highly fluorescent silica nanoparticles
From the themed collection: Recent Open Access Articles
Open Access Communication

Dual water-healable zwitterionic polymer coatings for anti-biofouling surfaces

Herein, we show for the first time drop-casting zwitterionic polymer colloidal particles onto different surfaces to obtain zwitterionic coatings with highly protein-repelling properties and dual self-healing capabilities.

Graphical abstract: Dual water-healable zwitterionic polymer coatings for anti-biofouling surfaces
From the themed collection: Recent Open Access Articles
Open Access Paper

Bioceramic microneedle arrays are able to deliver OVA to dendritic cells in human skin

Bioceramic arrays with high-aspect-ratio microneedles were able to penetrate human ex vivo skin and deliver their cargo to dendritic cells.

Graphical abstract: Bioceramic microneedle arrays are able to deliver OVA to dendritic cells in human skin
From the themed collection: Recent Open Access Articles
Open Access Paper

Protein-repellent and antimicrobial nanoparticle coatings from hyaluronic acid and a lysine-derived biocompatible surfactant

A water based, green and one-step strategy to functionalize surfaces of silicone catheters, poly(dimethylsiloxane) (PDMS), with antifouling and antimicrobial nanoparticles (hyaluronic acid–surfactant mixture) to avoid uncontrolled protein adsorption and microbial attachment is reported.

Graphical abstract: Protein-repellent and antimicrobial nanoparticle coatings from hyaluronic acid and a lysine-derived biocompatible surfactant
From the themed collection: Recent Open Access Articles
Open Access Paper

Electrospun organic–inorganic nanohybrids as sustained release drug delivery systems

Novel organic–inorganic nanohybrids have been prepared, and are found to provide long-term extended drug release.

Graphical abstract: Electrospun organic–inorganic nanohybrids as sustained release drug delivery systems
From the themed collection: Recent Open Access Articles
Open Access Paper

Barcoding chemical modifications into nucleic acids improves drug stability in vivo

The efficacy of nucleic acid therapies can be limited by unwanted degradation.

Graphical abstract: Barcoding chemical modifications into nucleic acids improves drug stability in vivo
From the themed collection: Recent Open Access Articles
Open Access Paper

Novel synthetic routes of large-pore magnetic mesoporous nanocomposites (SBA-15/Fe3O4) as potential multifunctional theranostic nanodevices

Superparamagnetic nanocomposites with a well-defined mesoporous matrix and mesoporous surface available for the high loading of drugs or biological entities.

Graphical abstract: Novel synthetic routes of large-pore magnetic mesoporous nanocomposites (SBA-15/Fe3O4) as potential multifunctional theranostic nanodevices
From the themed collection: Recent Open Access Articles
Open Access Paper

Rapid bioinspired mineralization using cell membrane nanofragments and alkaline milieu

Bone formation in vivo occurs in alkaline environment, which determines the optimal pKa of phosphatases, the optimal amount of calcium for mineral precipitation, and the spherical shape of initial minerals. Manipulation of environmental pH for in vitro synthesis of bone-like tissue, showed a markedly rapid mineralization with nanofragments and alkaline milieu.

Graphical abstract: Rapid bioinspired mineralization using cell membrane nanofragments and alkaline milieu
From the themed collection: Recent Open Access Articles
Open Access Communication

Seed-mediated synthesis of plasmonic gold nanoribbons using cancer cells for hyperthermia applications

MCF7 Cells biomineralize gold ions into long aspect-ratio nanoribbons in the presence of spherical nanoparticles as seeds with excellent photothermal properties.

Graphical abstract: Seed-mediated synthesis of plasmonic gold nanoribbons using cancer cells for hyperthermia applications
From the themed collection: Recent Open Access Articles
Open Access Paper

Enhanced biostability and cellular uptake of zinc oxide nanocrystals shielded with a phospholipid bilayer

The surface chemistry and charge of zinc oxide nanocrystals influence their behaviour in biological fluids. A novel lipid bilayer assembly is developed to shield ZnO nanocrystals improving their stability and cell internalization.

Graphical abstract: Enhanced biostability and cellular uptake of zinc oxide nanocrystals shielded with a phospholipid bilayer
From the themed collection: Recent Open Access Articles
Open Access Paper

Additives influence the phase behavior of calcium carbonate solution by a cooperative ion-association process

The role of biologically relevant additives on the phase behavior of calcium carbonate solution was studied by investigating their effects on the formation of amorphous calcium carbonate.

Graphical abstract: Additives influence the phase behavior of calcium carbonate solution by a cooperative ion-association process
From the themed collection: Recent Open Access Articles
Open Access Paper

Bioinspired reversible hydrogel adhesives for wet and underwater surfaces

A hydrogel-based wet adhesive with bioinspired microstructures can exhibit strong and reversible adhesion to wet and underwater surfaces.

Graphical abstract: Bioinspired reversible hydrogel adhesives for wet and underwater surfaces
From the themed collection: Recent Open Access Articles
Open Access Communication

Towards deployable meta-implants

The first step towards deployable meta-implants: design, manufacturing and proof of concept.

Graphical abstract: Towards deployable meta-implants
From the themed collection: Recent Open Access Articles
Open Access Review Article

Effects of bone substitute architecture and surface properties on cell response, angiogenesis, and structure of new bone

This paper presents an overview of the effect of porous biomaterial architecture on seeding efficiency, cell response, angiogenesis, and bone formation.

Graphical abstract: Effects of bone substitute architecture and surface properties on cell response, angiogenesis, and structure of new bone
From the themed collection: Recent Review Articles
Open Access Paper

Prevention of encrustation and blockage of urinary catheters by Proteus mirabilis via pH-triggered release of bacteriophage

The crystalline biofilms of Proteus mirabilis can seriously complicate the care of patients undergoing long-term indwelling urinary catheterisation.

Graphical abstract: Prevention of encrustation and blockage of urinary catheters by Proteus mirabilis via pH-triggered release of bacteriophage
From the themed collection: Recent Open Access Articles
Open Access Paper

Sub-zero temperature mechanically stable low molecular weight hydrogels

We show here a low molecular weight hydrogelator based on a functionalised dipeptide which is stable down to temperatures of −12 °C despite being made from >99% water. With the addition of glycerol this can be lowered further to −40 °C. At these colder temperatures there is no effect on the mechanical properties of the gels.

Graphical abstract: Sub-zero temperature mechanically stable low molecular weight hydrogels
From the themed collection: Recent Open Access Articles
Open Access Review Article

Contrast agents for cardiovascular magnetic resonance imaging: an overview

Contrast agents for Cardiovascular Magnetic Resonance (CMR) play a major role in research and clinical cardiology.

Graphical abstract: Contrast agents for cardiovascular magnetic resonance imaging: an overview
From the themed collection: Recent Review Articles
Open Access Paper

SU-8 based pyrolytic carbon for the electrochemical detection of dopamine

Here we investigated the electrochemical properties and dopamine (DA) detection capability of SU-8 photoresist based pyrolytic carbon (PyC) as well as its biocompatibility with neural cells.

Graphical abstract: SU-8 based pyrolytic carbon for the electrochemical detection of dopamine
From the themed collection: Recent Open Access Articles
Open Access Paper

Gold–iron oxide dimers for magnetic hyperthermia: the key role of chloride ions in the synthesis to boost the heating efficiency

To produce Au–FexOy dimers with outstanding heating performances under clinical magnetic hyperthermia conditions, here we report two synthesis routes, a two-pot and a one-pot method.

Graphical abstract: Gold–iron oxide dimers for magnetic hyperthermia: the key role of chloride ions in the synthesis to boost the heating efficiency
From the themed collection: Recent Open Access Articles
Open Access Paper

Enzymatic synthesis of a thiolated chitosan-based wound dressing crosslinked with chicoric acid

This work describes the enzymatic synthesis of multifunctional hydrogels for chronic wound treatment using thiolated chitosan and the natural polyphenol chicoric acid.

Graphical abstract: Enzymatic synthesis of a thiolated chitosan-based wound dressing crosslinked with chicoric acid
From the themed collection: Recent Open Access Articles
Open Access Paper

Biomimetic graphene for enhanced interaction with the external membrane of astrocytes

Phospholipids modified graphene oxide (GO–PL) shows enhanced compatibility with primary rat cortical astrocytes with respect to standard adhesion agents and non-functionalized GO.

Graphical abstract: Biomimetic graphene for enhanced interaction with the external membrane of astrocytes
From the themed collection: Recent Open Access Articles
Open Access Paper

Elastic serum-albumin based hydrogels: mechanism of formation and application in cardiac tissue engineering

The simplicity of making hydrogels with tunable mechanical properties from commercially available proteins is demonstrated for cardiac tissue engineering.

Graphical abstract: Elastic serum-albumin based hydrogels: mechanism of formation and application in cardiac tissue engineering
From the themed collection: Recent Open Access Articles
Open Access Paper

Dual controlled delivery of squalenoyl-gemcitabine and paclitaxel using thermo-responsive polymeric micelles for pancreatic cancer

A thermoresponsive block copolymer has been developed with the capability to co-carry two drug molecules and to augment their cytotoxic properties via direct cell membrane interaction with cancer cells.

Graphical abstract: Dual controlled delivery of squalenoyl-gemcitabine and paclitaxel using thermo-responsive polymeric micelles for pancreatic cancer
From the themed collection: Recent Open Access Articles
Open Access Communication

Tuneable plasmonic gold dendrimer nanochains for sensitive disease detection

We report the development of a tuneable plasmonic nanochain immunoassay with increased sensitivity over traditional monodisperse nanoparticle lateral flow tests.

Graphical abstract: Tuneable plasmonic gold dendrimer nanochains for sensitive disease detection
From the themed collection: Recent Open Access Articles
Open Access Paper

A hydroxamic acid–methacrylated collagen conjugate for the modulation of inflammation-related MMP upregulation

The selective covalent coupling of hydroxamic acid functions on to methacrylated type I collagen led to UV-cured networks with inherent MMP-modulating capability and enhanced proteolytic stability.

Graphical abstract: A hydroxamic acid–methacrylated collagen conjugate for the modulation of inflammation-related MMP upregulation
From the themed collection: Recent Open Access Articles
Open Access Paper

Influence of charged groups on the cross-linking efficiency and release of guest molecules from thiol–ene cross-linked poly(2-oxazoline) hydrogels

This study concerns hydrogels obtained from poly(oxazolines) bearing charged groups and their effect on the loading and release of guest molecules.

Graphical abstract: Influence of charged groups on the cross-linking efficiency and release of guest molecules from thiol–ene cross-linked poly(2-oxazoline) hydrogels
From the themed collection: Recent Open Access Articles
Open Access Paper

Rapid formulation of redox-responsive oligo-β-aminoester polyplexes with siRNA via jet printing

Novel reduction responsive oligo-β-aminoesters were successfully synthesized and condensed with siRNA through an inkjet method, thus showing promising biological response.

Graphical abstract: Rapid formulation of redox-responsive oligo-β-aminoester polyplexes with siRNA via jet printing
From the themed collection: Recent Open Access Articles
Open Access Paper

Effective control of the intrinsic DNA morphology by photosensitive polyamines

Changes occurring in the intrinsic B-DNA morphology upon binding to molecular photoswitches.

Graphical abstract: Effective control of the intrinsic DNA morphology by photosensitive polyamines
From the themed collection: Recent Open Access Articles
Open Access Paper

Surface enhancement of a molecularly imprinted polymer film using sacrificial silica beads for increasing L-arabitol chemosensor sensitivity and detectability

Sacrificial silica beads, used for increasing the specific surface area of a molecularly imprinted polymer film, improve the performance of the chemosensor.

Graphical abstract: Surface enhancement of a molecularly imprinted polymer film using sacrificial silica beads for increasing l-arabitol chemosensor sensitivity and detectability
From the themed collection: Recent Open Access Articles
Open Access Review Article

Surface modification strategies for combating catheter-related complications: recent advances and challenges

This review summarizes the progress made in addressing bacterial colonization and other surface-related complications arising from catheter use.

Graphical abstract: Surface modification strategies for combating catheter-related complications: recent advances and challenges
From the themed collection: Recent Review Articles
Open Access Paper

Single cell analysis of proliferation and movement of cancer and normal-like cells on nanowire array substrates

Performing single cell analysis can reveal the existence of different cell populations on nanowire arrays.

Graphical abstract: Single cell analysis of proliferation and movement of cancer and normal-like cells on nanowire array substrates
From the themed collection: Recent Open Access Articles
Open Access Communication

Biocompatible pH-responsive nanoparticles with a core-anchored multilayer shell of triblock copolymers for enhanced cancer therapy

pH-Responsive drug nanocarriers were made via facile self-assembly, showing excellent stability in bio-media (50% PBS/FBS) and enhanced drug efficacy towards cancer cells.

Graphical abstract: Biocompatible pH-responsive nanoparticles with a core-anchored multilayer shell of triblock copolymers for enhanced cancer therapy
From the themed collection: Recent Open Access Articles
Open Access Paper

Combinatorial delivery of bioactive molecules by a nanoparticle-decorated and functionalized biodegradable scaffold

The combination of supportive biomaterials and bioactive factors to stimulate endogenous progenitor cells is of key interest for the treatment of conditions in which intrinsic bone healing capacities are compromised.

Graphical abstract: Combinatorial delivery of bioactive molecules by a nanoparticle-decorated and functionalized biodegradable scaffold
From the themed collection: Recent Open Access Articles
Open Access Paper

Dendritic polyglycerol anions for the selective targeting of native and inflamed articular cartilage

Dye-conjugated polyanions show high affinities toward native and inflamed cartilage dependent on the anionic moiety and the condition of the tissue.

Graphical abstract: Dendritic polyglycerol anions for the selective targeting of native and inflamed articular cartilage
From the themed collection: Recent Open Access Articles
Open Access Paper

Detection of Posner's clusters during calcium phosphate nucleation: a molecular dynamics study

Molecular dynamics simulations of calcium and phosphate ions in water show that Posner-like clusters originate during the aggregation process.

Graphical abstract: Detection of Posner's clusters during calcium phosphate nucleation: a molecular dynamics study
From the themed collection: Recent Open Access Articles
Open Access Review Article

Bibliographic review on the state of the art of strontium and zinc based regenerative therapies. Recent developments and clinical applications

This review brings up to date the state of the art of strontium and zinc based regenerative therapies, both having a promoting effect on tissue formation and a role inhibiting resorption in musculoskeletal disorders.

Graphical abstract: Bibliographic review on the state of the art of strontium and zinc based regenerative therapies. Recent developments and clinical applications
From the themed collection: Recent Open Access Articles
Open Access Paper

Turn-on fluorescence detection of protein by molecularly imprinted hydrogels based on supramolecular assembly of peptide multi-functional blocks

Supramolecular in-cavity target–peptide complex for self-reporting imprinted polymers.

Graphical abstract: Turn-on fluorescence detection of protein by molecularly imprinted hydrogels based on supramolecular assembly of peptide multi-functional blocks
From the themed collection: Recent Open Access Articles
Open Access Paper

Tuning HIV drug release from a nanogel-based in situ forming implant by changing nanogel size

This paper reports an in situ forming implant based on responsive nanogels that gives tuneable long-acting drug release.

Graphical abstract: Tuning HIV drug release from a nanogel-based in situ forming implant by changing nanogel size
From the themed collection: Recent Open Access Articles
54 items

About this collection

This collection contains recent Open Access articles published by Journal of Materials Chemistry B, the home for high impact applications, properties and synthesis of exciting new materials for biology and medicine. New articles will be added to this webpage as soon as possible after publication.

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