Critical Review
Dengue-virosensor: advancement of dengue virus-based biosensors
Novel literature covering advancements in the field of dengue diagnostics.
Critical Review
Paper-based point of care diagnostics for cancer biomarkers
Advancements in assay design, detection techniques, signal transduction and enhancement strategies using smart nanomaterials.
Communication
Paper sensors for the measurement of nitric oxide release from endothelial cells
Nitric oxide (NO) is a ubiquitous and important biological mediator.
Communication
Paper-based sensing of pancreatic-cancer biomarker α-chymotrypsin through turn-on lanthanide-luminescence
An inexpensive and robust paper-based sensor has been developed to detect pancreatic cancer biomarker α-chymotrypsin through turn-on visible light emitting Tb3+-luminescence for the first time.
Paper
Headspace paper-based analytical device for ammonia quantification in human biological samples
The simple and low-cost contact-less headspace paper-based colorimetric device (hPAD) was established for improving the selective detection of ammonia levels in human samples.
Paper
Leveraging synthetic imagery and YOLOv8 for a novel colorimetric approach to paper-based point-of-care male fertility testing
The development of paper-based systems has revolutionized point-of-care (POC) applications by enabling rapid, robust, accurate and sensitive biochemical analysis, infectious disease diagnosis, and fertility monitoring.
Paper
An approach to use machine learning to optimize paper immunoassays for SARS-CoV-2 IgG and IgM antibodies
Optimizing paper immunoassay conditions for diagnostic accuracy is often achieved by tuning running conditions in a trial and error manner. We report the use of machine learning to optimize an assay for SARS-CoV-2 IgG and IgM antibodies.
Paper
Monolith-modified cellulose paper for biochemical sensing applications
A microfluidic paper-based analytical device (μPAD) modified with a poly(GMA-co-EDMA) monolith for rapid tuberculosis detection.
Paper
A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action
Soft, skin-mounted microfluidic devices can collect microliter volumes of eccrine sweat and are capable of in situ real-time analysis of different biomarkers to assess physiological state and health.
About this collection
In recent years, the need for accessible, affordable, and reliable diagnostic methods has become increasingly critical, especially in low-resource settings. The advent of paper-based point-of-care (POC) diagnostic platforms has emerged as a promising solution to meet this demand. This collection aims to explore the advancements, challenges, and future directions in developing and applying paper-based POC diagnostics. It highlights innovative designs, materials, and technologies that enhance the functionality, sensitivity, and specificity of these platforms. Additionally, it covers integration of paper-based systems with digital health technologies for data analysis and remote health monitoring, contributing to the advancement of telemedicine and decentralized healthcare.
Guest Editors: Thiago Paixão (Universidade de São Paulo, Brazil), Daniel Citterio (Keio University, Japan) and Willam de Araujo (Universidade Estadual de Campinas, Brazil)