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Themed collection Recent Open Access Articles

8 items
Open Access Highlight

Neglected sulfur(VI) pharmacophores in drug discovery: exploration of novel chemical space by the interplay of drug design and method development

The key learnings of the utilization of sulfoximines, sulfondiimines and sulfonimidamides in drug discovery at Bayer AG are shared.

Graphical abstract: Neglected sulfur(vi) pharmacophores in drug discovery: exploration of novel chemical space by the interplay of drug design and method development
Open Access Review Article

Progress in the synthesis of perylene bisimide dyes

Rapid progress in the synthesis of perylene bisimide dyes gave an old scaffold new life.

Graphical abstract: Progress in the synthesis of perylene bisimide dyes
Open Access Research Article

Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme

The first example of a hydroxylammonium derivative that causes a specific covalent modification of the active-site lysine residue of an aldolase enzyme, which is a promising target for anti-bacterial drug discovery, is reported.

Graphical abstract: Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme
From the themed collection: Recent Open Access Articles
Open Access Research Article

Trioxotriangulene with carbazole: a donor–acceptor molecule showing strong near-infrared absorption exceeding 1000 nm

A donor–acceptor type trioxotriangulene neutral radical derivative having three carbazolyl groups as electron-donors was newly synthesized, and exhibited a strong near-infrared photo absorption over 1000 nm.

Graphical abstract: Trioxotriangulene with carbazole: a donor–acceptor molecule showing strong near-infrared absorption exceeding 1000 nm
From the themed collection: Recent Open Access Articles
Open Access Research Article

Visible light-mediated photo-oxygenation of arylcyclohexenes

The photo-oxygenation of versatile arylcycloalkenes proceeds through zwitterionic intermediates and provides access to new allyl hydroperoxides and endoperoxides.

Graphical abstract: Visible light-mediated photo-oxygenation of arylcyclohexenes
From the themed collection: Recent Open Access Articles
Open Access Research Article

Direct methylation and carbonylation of in situ generated arynes via HDDA-Wittig coupling

A high-efficiency HDDA-Wittig coupling strategy for synthesis of fully functionalized benzenes is reported. Direct methylation and carbonylation of aryne intermediates reacted with phosphorus ylides to form the carbonylated 2,3-dihydro-1H-indenes.

Graphical abstract: Direct methylation and carbonylation of in situ generated arynes via HDDA-Wittig coupling
From the themed collection: Recent Open Access Articles
Open Access Research Article

Oxidative selenofunctionalization of allenes: convenient access to 2-(phenylselanyl)-but-2-enals and 4-oxo-3-(phenylselanyl)pent-2-enoates

The controlled preparation of two types of α-seleno-α,β-unsaturated carbonyls, namely, α-selenoenals and α-selenoenones, have been accomplished.

Graphical abstract: Oxidative selenofunctionalization of allenes: convenient access to 2-(phenylselanyl)-but-2-enals and 4-oxo-3-(phenylselanyl)pent-2-enoates
From the themed collection: Recent Open Access Articles
Open Access Research Article

Radical addition of ketones and cyanide to olefins via acid catalyzed formation of intermediate alkenyl peroxides

γ-Cyanoketones are formed by double radical addition from olefins, ketones and sulfonyl cyanides via reactive alkenyl peroxide intermediates.

Graphical abstract: Radical addition of ketones and cyanide to olefins via acid catalyzed formation of intermediate alkenyl peroxides
From the themed collection: Recent Open Access Articles
8 items

About this collection

This collection contains recent Open Access articles published from Organic Chemistry Frontiers . New articles will be added to this webpage as soon as possible after publication.

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