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Themed collection The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways

16 items
Editorial

Introduction to the themed issue ‘The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways’

Sun exposure stimulates vitamin D production in addition to several immunomodulatory pathways. Fifteen perspectives in this themed issue aim to distinguish the contribution of vitamin D-dependent and independent pathways, initiated by UV radiation exposure, to beneficial health outcomes.

Graphical abstract: Introduction to the themed issue ‘The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways’
Perspective

Sunlight exposure is just one of the factors which influence vitamin D status

Studies on the determinants of vitamin D status have tended to concentrate on input – exposure to ultraviolet B radiation and the limited sources in food.

Graphical abstract: Sunlight exposure is just one of the factors which influence vitamin D status
From the themed collection: 2017 Perspective articles collection
Perspective

The role of UV radiation and vitamin D in the seasonality and outcomes of infectious disease

Individual components of solar radiation, UVA, UVB and heat generation, are linked to their downstream immune functions, inducing vitamin D production, demonstrating a great degree of overlap between various components.

Graphical abstract: The role of UV radiation and vitamin D in the seasonality and outcomes of infectious disease
From the themed collection: 2017 Perspective articles collection
Perspective

Challenge and perspective: the relevance of ultraviolet (UV) radiation and the vitamin D endocrine system (VDES) for psoriasis and other inflammatory skin diseases

Focussing on the UV induced cutaneous synthesis of vitamin D, this review gives an update on the relevance of the VDES and of UV radiation for the management of psoriasis and other inflammatory skin diseases.

Graphical abstract: Challenge and perspective: the relevance of ultraviolet (UV) radiation and the vitamin D endocrine system (VDES) for psoriasis and other inflammatory skin diseases
From the themed collection: 2017 Perspective articles collection
Perspective

ASTHMA – comparing the impact of vitamin D versus UVR on clinical and immune parameters

Asthma is estimated to affect more than 300 million individuals worldwide. Vitamin D is increasingly believed to beneficially influence asthma incidence and control, likely due to effects on innate and adaptive immunity. The primary mechanism for increasing vitamin D in the body is via UVB radiation of skin, however whether UVB has comparable effects to vitamin D on relevant immune mechanisms and asthma is unclear.

Graphical abstract: ASTHMA – comparing the impact of vitamin D versus UVR on clinical and immune parameters
From the themed collection: 2017 Perspective articles collection
Perspective

The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways. Blood pressure and cardiovascular disease

UV photoreduces nitrogen oxides sequestered in the skin. The resulting NO moves to the systemic circulation where it vasodilates and lowers BP.

Graphical abstract: The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways. Blood pressure and cardiovascular disease
From the themed collection: 2017 Perspective articles collection
Perspective

Ultraviolet radiation, vitamin D and the development of obesity, metabolic syndrome and type-2 diabetes

Obesity prevalence is increasing around the world; however, the causes are not known. Here, we discuss moderate sun exposure as a potential modifier of obesity and metabolic dysfunction, with a focus on sun-induced mediators such as vitamin D and nitric oxide.

Graphical abstract: Ultraviolet radiation, vitamin D and the development of obesity, metabolic syndrome and type-2 diabetes
From the themed collection: 2017 Perspective articles collection
Perspective

The relationship between sun exposure and all-cause mortality

Women with low sun exposure are at a dose-dependently increased risk of all-cause mortality, mainly due to an increased risk of death from cardiovascular or noncancer/noncardiovascular disease compared higher exposure.

Graphical abstract: The relationship between sun exposure and all-cause mortality
From the themed collection: 2017 Perspective articles collection
Open Access Perspective

Are low sun exposure and/or vitamin D risk factors for type 1 diabetes?

Ultraviolet radiation and vitamin D, with their known immunosuppressive effects, have the potential to delay or inhibit type 1 diabetes.

Graphical abstract: Are low sun exposure and/or vitamin D risk factors for type 1 diabetes?
From the themed collection: 2017 Perspective articles collection
Perspective

A short history of phototherapy, vitamin D and skin disease

The earliest record between sun exposure and skin disease goes back five millennia to the ancient Egyptians. Cod liver oil was a folk remedy prior to 1789 and with the observation that sunlight prevented the “appearance of mycelial fungi” in 1877 the modern era commenced with the treatment of cutaneous Mycobacterium tuberculosis.

Graphical abstract: A short history of phototherapy, vitamin D and skin disease
From the themed collection: 2017 Perspective articles collection
Perspective

UVB radiation, vitamin D and multiple sclerosis

Acheson et al. (1960) observed an inverse relationship between sunlight exposure and the incidence of Multiple Sclerosis (MS).

Graphical abstract: UVB radiation, vitamin D and multiple sclerosis
From the themed collection: 2017 Perspective articles collection
Perspective

Does sunlight protect us from cancer?

The Ultraviolet (UV) radiation contained in sunlight is a powerful mutagen and immune suppressant which partly explains why exposure to solar UV is the biggest risk factor for the development of cutaneous tumours.

Graphical abstract: Does sunlight protect us from cancer?
From the themed collection: 2017 Perspective articles collection
Perspective

Time outdoors, blood vitamin D status and myopia: a review

Myopia is a major public health concern throughout the world but whether vitamin D played a role in myopia development remains unknown.

Graphical abstract: Time outdoors, blood vitamin D status and myopia: a review
From the themed collection: 2017 Perspective articles collection
Perspective

Lung development

Recent equivocal results in high profile randomised controlled trials suggest that the impact of vitamin D deficiency on lung development is complex. In this narrative review we summarise our current understanding of the link between UV exposure, vitamin D and lung development.

Graphical abstract: Lung development
From the themed collection: 2017 Perspective articles collection
Open Access Perspective

UVR: sun, lamps, pigmentation and vitamin D

Exposure to ultraviolet radiation (UVR) has important and significant consequences on human health.

Graphical abstract: UVR: sun, lamps, pigmentation and vitamin D
From the themed collection: 2017 Perspective articles collection
Perspective

The role of UVR and vitamin D on T cells and inflammatory bowel disease

Vitamin D/UVR effects on T cells that are important in the development of inflammatory bowel disease (IBD).

Graphical abstract: The role of UVR and vitamin D on T cells and inflammatory bowel disease
From the themed collection: 2017 Perspective articles collection
16 items

About this collection

This issue of Photochemical and Photobiological Sciences contains 15 perspectives that seek to distinguish the contribution of vitamin D-dependent and vitamin D-independent pathways, initiated by UV radiation exposure, to beneficial health outcomes.

These articles are all free to access for 6 months. To read these articles, log in with your personal/institutional access or sign up for a free publishing personal account.

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