Themed collection Nanoscale 2026 Emerging Investigators
Nanocarrier-empowered aggregation-induced luminescence and its therapeutic promise in oncology
This article focused on the key bottlenecks in the in vivo applications of AIEgens and systematically reviewed strategies for combining nanocarriers with them to address issues such as biocompatibility and biosafety.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04932F
Site-selective functionalization of solution-processed transition metal dichalcogenides for vertical and lateral covalent networks and heterostructures
Nanoscale, 2026, Accepted Manuscript
https://doi.org/10.1039/D5NR05499K
Recent ultratrace per- and polyfluoroalkyl substance (PFAS) detectors
Ultratrace PFAS detectors employing organic, polymeric, and nanomaterials transduce molecular recognition into optical, electrochemical, or resistive signals.
Nanoscale, 2026,18, 5709-5726
https://doi.org/10.1039/D5NR04376J
Designer charge-transfer van der Waals heterostructures
Programmable interlayer charge transfer in two-dimensional van der Waals heterostructures underpins a wide range of emergent quantum phenomena, ranging from excitonic dynamics and light–matter interactions to various correlated electron states.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D6NR00005C
Solar-energy-driven value-added oxidation processes
The value-added utilization of photogenerated holes.
Nanoscale, 2026,18, 4661-4672
https://doi.org/10.1039/D5NR05234C
Recent advances on the hydrogen spillover effect in the design of electrocatalysts
Hydrogen spillover has emerged as a pivotal mechanism enabling the directional transport of active hydrogen species (*H) in electrocatalytic systems, providing a fundamental design strategy for advanced catalyst engineering.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04837K
Surface functionalization of graphene-based materials: enhancing the performance and sustainability of cement composites
This Minireview highlights the recent advancements, challenges and future prospects in the field of the application of functionalized graphene-family materials in cement composites.
Nanoscale, 2026,18, 1316-1328
https://doi.org/10.1039/D5NR04456A
Energy-conversion nano/micromaterial based retinal prostheses for vision restoration
This review focuses on retinal prostheses using energy-conversion nano/micromaterials (photovoltaic, piezoelectric, upconversion, and photothermal), which enable wireless/self-powered operation with advantages like high sensitivity and resolution.
Nanoscale, 2025,17, 26621-26641
https://doi.org/10.1039/D5NR02287H
Unveiling quantum phases in two-dimensional materials with optical quasiparticle probes
We establish a unified framework showing how optical spectroscopies reveal the intricate coupling between quasiparticles, dimensionality, and interations in two-dimensional materials.
Nanoscale, 2025,17, 26010-26023
https://doi.org/10.1039/D5NR03359D
Challenges and strategies for first-principles simulations of two-dimensional magnetic phenomena
This review introduces key concepts and tools for modelling 2D magnets with DFT, covering magnetism basics, challenges like spin order, and methods to extract Hamiltonian parameters and critical temperatures for various anisotropies.
Nanoscale, 2025,17, 24955-24989
https://doi.org/10.1039/D4NR05503A
g-C3N5-based photocatalysts for energy and environmental applications: insights into properties, structural modifications, challenges, and future directions
The growing demand for sustainable energy and environmental remediation has intensified the search for efficient, metal-free catalysts.
Nanoscale, 2025,17, 18534-18559
https://doi.org/10.1039/D5NR02485D
Computational progress of designing single-atom alloy catalysts for methane activation
Nonoxidative coupling of methane to value-added hydrocarbons remains a major challenge in catalysis. Computational modeling plays a crucial role in uncovering the fundamental chemistry and guiding the design of efficient catalysts for this reaction.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR05405B
Advanced catalyst design and mechanistic insights in electrocatalytic upcycling of PET-derived ethylene glycol and coupled electrolysis systems
This review summarizes electrocatalytic PET upcycling to C1/C2 oxygenates, covering PET depolymerization, EGOR pathways, catalyst design, paired electrolysis, plus outlooks on durability, separation, and system design.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR05358G
Leveraging DNA-based biomaterials for advanced cancer immunotherapy
Outlining programmable DNA-based biomaterials for precise immunomodulation within tumor and lymphoid tissues, activating antigen-presenting cells and T cells to drive synergistic antitumor immunity.
Nanoscale, 2026,18, 6768-6786
https://doi.org/10.1039/D5NR04775G
Mechanisms and Potential Applications of Technologies for Detecting Specific Polyfluoroalkyl Substances via Nano-level Interactions
Nanoscale, 2026, Accepted Manuscript
https://doi.org/10.1039/D5NR05521K
Carbolong complexes: an emerging class of metallaaromatics for next-generation functional materials
Carbolong metallaaromatics combine metal–carbon conjugation and Craig aromaticity, enabling efficient charge transport and photoresponsive functions in molecular electronics, photovoltaic devices, and photothermal materials.
Nanoscale, 2026,18, 5621-5637
https://doi.org/10.1039/D5NR05504K
Bioinspired multi-compartment mesoporous nanoreactors: modular assembly and functional applications
Bioinspired multi-compartment mesoporous nanoreactors.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D6NR00015K
MXene/biomacromolecule composites: structures, properties, fabrication and applications
Biomacromolecule-regulated MXene composites form hierarchical structures with stable transport pathways, enabling multifunctional systems for EMI shielding, actuation, biomedicine, energy storage, electronics, and water purification.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR05039A
Non-traditional granular magnetoresistive devices: a short review
This review is focused on non-traditional granular magnetoresistive (MR) sensors. It discusses the underlying physical mechanisms, material configurations, fabrication strategies, and MR device performance evolution over the past two decades.
Nanoscale, 2026,18, 4568-4580
https://doi.org/10.1039/D5NR04769B
Interfacial mechanisms in the freezing of polymer solutions
Freezing of polymer solutions plays a central role in processes such as cryopreservation, porous material synthesis, and environmental remediation.
Nanoscale, 2026,18, 3453-3471
https://doi.org/10.1039/D5NR04002G
Advances and challenges in aqueous zinc-ion batteries for extreme environmental adaptability
Strategies boosting AZIBs’ extreme-condition resilience via electrode/electrolyte/interface engineering, addressing dendrites, side reactions, and thermal instability.
Nanoscale, 2026,18, 1740-1764
https://doi.org/10.1039/D5NR04573H
Progress on perovskite photodetectors for optical communications
This review summarizes the material properties, device structure, integration design, and the latest optical communication application scenarios of perovskite photodetectors.
Nanoscale, 2026,18, 1693-1739
https://doi.org/10.1039/D5NR03957F
Nanostructured self-humidifying membrane electrode assemblies: toward efficient water management in air-cooled proton exchange membrane fuel cells
By integrating material selection with structural design, tailored approaches can be applied to specific components to realize internal self-humidification functionality.
Nanoscale, 2025,17, 27704-27733
https://doi.org/10.1039/D5NR03720D
Design and application of proton gradient-based pH-responsive nanomaterials in the tumor microenvironment
The five nanoparticles target the tumor acidic microenvironment through the mechanism of (1) ionizable groups and (2) pH-sensitive chemical bonds.
Nanoscale, 2025,17, 27042-27065
https://doi.org/10.1039/D5NR02990B
Metal-organic chemical vapour deposition of van der Waals 2D chalcogenides and heterostructures: a review
This review highlights recent progress in metal-organic chemical vapour deposition of wafer-scale 2D chalcogenides and future guidelines. Key topics include precursor chemistry, growth mechanisms, epitaxy, heterostructures, and doping strategies.
Nanoscale, 2025,17, 22606-22628
https://doi.org/10.1039/D5NR02265G
Integration of 2D materials for high-performance perovskite solar cells
In this mini-review, we reviewed the role played by 2D materials as additives in PSCs and their effects on carrier transport and stability and put forward some prospects for the preparation of high-performance PSCs.
Nanoscale, 2025,17, 22033-22049
https://doi.org/10.1039/D5NR01504A
Leveraging metal sites in doped metal halide perovskites for enhanced photocatalysis: fundamentals and applications
This review systematically reveals the in-depth relationship between doping strategies, property regulation, and functional applications as well as promotes more efficient applications of metal-doped MHP materials for photocatalysis.
Nanoscale, 2025,17, 18446-18476
https://doi.org/10.1039/D5NR02472B
Highly efficient charge inversion in dense periodic nanoporous framework membranes
Monovalent cations induce charge inversion in the TpPa-SO3H membrane, enabling reversible cation/anion selectivity via synergistic pore–pore interactions at ultrahigh pore density and saturated ion adsorption in nanoconfined channels.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D6NR00034G
Coacervate microenvironments modulate fluorescent dye behaviour and Förster energy transfer dynamics
Coacervation induced the aggregation and fluorescence quenching of pyranine (PN) and sulphorhodamine B (SRh). Nanoscale confinement of PN and SRh within the coacervate phase enables efficient Förster energy transfer.
Nanoscale, 2026,18, 6259-6263
https://doi.org/10.1039/D5NR04690D
Non-invasive modulation of carrier injection efficiency via electronic phase separation at organic/inorganic interfaces
Magnetic-field-controlled phase separation in LPCMO dynamically shifts the interfacial barrier, offering a non-invasive route for amplifying carrier injection in hybrid organic/inorganic devices.
Nanoscale, 2025,17, 27849-27857
https://doi.org/10.1039/D5NR04434K
Structural distortions control scaling of exciton binding energies in two-dimensional Ag/Bi double perovskites
Structural distortions in Ag/Bi quasi-2D double perovskites are responsible for the unexpected trend in the exciton binding energies.
Nanoscale, 2025,17, 23924-23929
https://doi.org/10.1039/D5NR03010B
Molybdenum-Driven Electronic Restructuring of Iron Carbides Unlocks Faster Volmer Kinetics in Alkaline Hydrogen Evolution
Nanoscale, 2026, Accepted Manuscript
https://doi.org/10.1039/D5NR05502D
Anchored nanocatalysts enable efficient oxygen reduction in barium cobaltite cathodes
Ex-solved metal nanoparticles are anchored on solid oxide fuel cell (SOFC) cathodes, enabling accelerated oxygen reduction rate.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04551G
Super Electron Transfer Channels Enable Prussian-Blue-Like Nanocarbon Felts for Ultrasensitive Glucose Biosensing Applications
Nanoscale, 2026, Accepted Manuscript
https://doi.org/10.1039/D5NR05292K
Light-driven cation pumping in atomic-level van der Waals heterostructures towards efficient osmotic energy harvesting
Cascaded vdW heterostructure membranes convert light into built-in potential to drive directional ion transport for enhanced osmotic energy conversion.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D6NR00014B
Modulating the electronic structure of cobalt sites using zinc to promote the oxygen evolution electrocatalysis
Zn incorporated into Co layered (oxy)hydroxides modulates the electronic states of Co through Zn–O–Co bridging motifs. This induces an intermediate-spin state of the Co site, facilitating Co–oxo formation and boosting the OER performance.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D6NR00253F
The bis-salphen Zn(II) unit: a versatile building block for self-assembled heteroleptic coordination cages
The bis-salphen motif functions as a versatile building unit for heteroleptic prismatic coordination cages showing a ligand-dependent "on-off" emission behaviour.
Nanoscale, 2026,18, 7002-7009
https://doi.org/10.1039/D5NR04564A
Unlocking high-voltage sodium ion batteries with MOF-derived Cr2S3@C anode materials
Nernst-based thermodynamic screening identifies Cr2S3 as a low-potential anode material. Coupled conversion–alloying reactions enable high-voltage Na-ion full cells with enhanced energy density.
Nanoscale, 2026,18, 6967-6975
https://doi.org/10.1039/D5NR05088J
Solvothermal synthesis of spherical CoMnO3 catalysts for efficient trace ethylene removal under high humidity
Cetyltrimethylammonium bromide-assisted synthesis yields mesoporous MnCoOx spheres with superior activity and exceptional water resistance, enabled by Mn–Co synergy and abundant oxygen vacancies.
Nanoscale, 2026,18, 6986-7001
https://doi.org/10.1039/D5NR05508C
InGaN/GaN multi-quantum well LED array for short-distance optical links
An InGaN/GaN multi-quantum-well LED array is designed and fabricated for use in high-speed multi-channel data transmission systems.
Nanoscale, 2026,18, 6976-6985
https://doi.org/10.1039/D5NR04586J
Molecularly modified ultrathin Al2O3 layers as proton-conductive, oxygen-impermeable nanomembranes for catalytic surfaces
Ultrathin inorganic oxide coatings can improve selectivity in photo- and electrocatalysis, but they also bury active sites and impede transport of the desired reactants.
Nanoscale, 2026,18, 6894-6905
https://doi.org/10.1039/D5NR04262C
W2N3 Nanodot/2D C3N4 Heterostructures with Interfacial Covalent Bonding Toward Pt-Free Photocatalytic Hydrogen Evolution
Nanoscale, 2026, Accepted Manuscript
https://doi.org/10.1039/D5NR05506G
Random sequence-guided crosslinking for on-demand injectable HA–DNA hydrogels supporting neural progenitor cells
Hyaluronic acid (HA) hydrogels crosslinked through DNA hybridization (HA–DNA hydrogels) offer a programmable and cell-compatible platform for regenerative medicine.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR05011A
Bio-based PEDOT: nanocellulose hybrids as efficient hole-transport layers for photoelectrochemical devices
PEDOT polymerized in the presence of two NCC allomorphs enables the development of sustainable hole-transport materials that can match the performance of PEDOT:PSS, addressing a key challenge for environmentally compatible optoelectronic devices.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04688B
Analysis of transport mechanisms in superlattice FinFETs from room temperature to cryogenic temperature and discussion on continued scalability beyond 7 nm
Superlattice FinFETs, showing high performance and the capability for continuous scaling, are promising candidates for future logic devices.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04582G
X-ray photoelectron spectroscopy analysis of reference compounds for studying rechargeable Li-, Na-, and K-ion batteries
We built a unified XPS and HAXPES reference library for Li, Na, and K battery materials, binders, and salts. Optimized preparation and selective Os coating suppress charging and provide reliable fingerprints for SEI and surface chemistry.
Nanoscale, 2026,18, 6350-6358
https://doi.org/10.1039/D5NR04532K
Multilevel dynamic control of surface plasmon propagation direction using phase-change materials
Ultracompact asymmetric nanogrooves integrated with GST.
Nanoscale, 2026,18, 6342-6349
https://doi.org/10.1039/D5NR04634C
Completely degradable bilayer functional-ionic wood heterostructure-derived nanogenerator for eco-friendly power generation
A bilayer functional ionic wood heterostructure enables efficient triboelectric energy harvesting via strong polarization from oppositely functionalized cellulose nanostructures and rapid ionic charge transport.
Nanoscale, 2026,18, 6329-6341
https://doi.org/10.1039/D5NR04814A
Band structure engineering in porous g-C3N4via tailoring surface carbon for enhanced photocatalytic hydrogen evolution
For achieving enhanced hydrogen evolution activity, surface-carbon-modified porous ultrathin g-C3N4 nanosheets with high specific surface area, huge pore volume, narrowed bandgap and a more negative conduction band were synthesized via a CVD process.
Nanoscale, 2026,18, 6359-6368
https://doi.org/10.1039/D5NR04835D
Mechanically encoded strain-vector keys as physical unclonable functions
Optical physically unclonable functions based on mechanically encoded strain-vector keys are demonstrated as practical identifiers and cryptographic keys for mutual authentication and image encryption.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04377H
Tunable cation vacancy engineering of FeP toward efficient hydrogen evolution reaction
Tunable cation vacancy engineering of FeP leads to a volcano-type HER activity trend. An optimal vacancy level of 16.2% maximizes active sites and *H adsorption for efficient HER, while excessive vacancies induce severe oxidation to impede the HER.
Nanoscale, 2026,18, 5821-5830
https://doi.org/10.1039/D5NR04402B
A surfactant-mediated Ni/MgAl bifunctional catalyst for highly selective tandem conversion of acetone to methyl isobutyl ketone
A surfactant-assisted impregnation strategy was developed to construct a heterogeneous catalyst of Ni/MgAl-SDBS with coexistence of Ni0/Ni2+ species, which efficiently transformed acetone into methyl isobutyl ketone with a high selectivity of 94.5%.
Nanoscale, 2026,18, 5330-5336
https://doi.org/10.1039/D5NR04445F
Palladium-based polyelemental nanoparticles for ethanol oxidation reaction
The strain effect, ligand effect, and multisite synergy of palladium-based polyelemental nanoparticles enhance their activity and durability for ethanol oxidation reaction.
Nanoscale, 2026,18, 5347-5356
https://doi.org/10.1039/D5NR04574F
Lateral CO diffusion on micropatterned Ag/CuO arrays enables efficient CO2-to-C2+ electroreduction
Spatial lateral CO diffusion on micropatterned Ag/CuO arrays enables efficient C–C coupling for high-value CO2-to-C2+ electroreduction.
Nanoscale, 2026,18, 5337-5346
https://doi.org/10.1039/D5NR04711K
From batch to flow plasmon catalysis: revealing mass transport limits in Au@Pd nanocatalysts for Suzuki coupling
Transitioning plasmonic chemistry from batch to flow, we show that controlled mass transport in a flow reactor unlocks hot-carrier transfer in gram-scale Au@Pd–Al2O3 catalysts, tripling Suzuki coupling and enabling scalable light-driven synthesis.
Nanoscale, 2026,18, 5357-5370
https://doi.org/10.1039/D5NR03832D
Noble-metal-free recyclable electronic nanoinks for wireless wearable sensors
This study elucidates how functional property changes in printed sensors across multiple reuse phases and presents a surface-cleaning method for regenerating printable nanoinks.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04828A
Large-scale synthesis of zinc oxide-supported indium single-atom catalysts for efficient electrocatalytic CO2 reduction reaction
We report the large-scale synthesis of ZnO-supported In single-atom catalysts using a micro-impinging stream reactor. The catalysts achieve high formate selectivity (85%) and outstanding long-term stability (>40 h) toward CO2 reduction reaction.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR04922A
First-principles prediction of 2D non-centrosymmetric Al2O3 with tunable piezoelectric and electric-field-responsive properties
Using DFT and global structure search, a new non-centrosymmetric Al2O3 is predicted. The structure can be tuned by using an external electric field. These results offer a pathway toward electric-field-gated non-volatile memory devices.
Nanoscale, 2026,18, 4757-4767
https://doi.org/10.1039/D5NR04553C
Synchronizing carrier extraction and dielectric coupling in a hierarchical homometallic plasmonic catalyst for light-driven nitrate reduction
A hierarchical homometallic plasmonic AuL–S catalyst enables precise dielectric matching for optimal carrier extraction and plasmon coupling capabilities towards light-driven plasmonic catalysis of nitrate reduction into ammonia.
Nanoscale, 2026,18, 4117-4126
https://doi.org/10.1039/D5NR04795A
Performance and stability evaluation of LaF3 thin-film waveplates for high-power 266 nm laser applications
Thin-film LaF3 waveplates exhibit superior stability and low retardance drift under changing humidity compared with all-SiO2 waveplates, supporting reliable high-power laser operation at a 266 nm wavelength.
Nanoscale, 2026,18, 4127-4134
https://doi.org/10.1039/D5NR04985G
The role of nickel hydroxide phases in wastewater electrolysis for sustainable green hydrogen production
Nickel hydroxide bifunctional electrocatalysts for sustainable green hydrogen production.
Nanoscale, 2026, Advance Article
https://doi.org/10.1039/D5NR05037E
Enhanced electrocatalytic activity for nitrobenzene reduction via p–d orbital hybridization in single- and dual-atom catalysis
Aniline (PhNH2) is usually prepared via the hydrogenation of nitrobenzene (PhNO2) under high-temperature and high-pressure conditions.
Nanoscale, 2026,18, 3682-3697
https://doi.org/10.1039/D5NR04666A
Ultrasound activated bowl-like nanomotors release nitric oxide for enhanced thrombus therapy
By integrating sonodynamic therapy, asymmetric morphology-enhanced mobility, and NO-mediated multimodal thrombolysis, AB-LC effectively enhances thrombolytic therapy.
Nanoscale, 2026,18, 3135-3142
https://doi.org/10.1039/D5NR04212G
A flexible plasmonic SERS hydrogel patch for metabolite sensing on bio-interfaces
A flexible stretchable SERS hydrogel patch is developed by using self-assembled Ag nanoparticle films for metabolite sensing at bio-interfaces.
Nanoscale, 2026,18, 3105-3113
https://doi.org/10.1039/D5NR04403K
Precise control of InP quantum dot growth via recyclable indium adducts
Master of Puppets: By forming adducts with the Indium precursor, triarylphosphines are able to exert control over InP QD formation, allowing targeted choice of QD size and their optoelectronic properties.
Nanoscale, 2026,18, 3128-3134
https://doi.org/10.1039/D5NR03865K
Rational design of benzoimidazoisoindolone-linked conjugated ladder polymer for enhanced visible-light-driven photocatalytic water oxidation
A benzoimidazoisoindolone-linked coplanar ladder polymer was rationally designed and exhibited a 2-times higher visible-light-driven photocatalytic water oxidation performance than its imide-linked linear analogue.
Nanoscale, 2026,18, 3114-3119
https://doi.org/10.1039/D5NR04396D
High-valence Ir single atoms enhance oxygen evolution electrocatalysis
High-valence Ir single atoms were anchored on a NiS2 support, which exhibited superior OER catalytic activity by lowering the energy barrier and accelerating the reaction kinetics in the OER process.
Nanoscale, 2026,18, 3120-3127
https://doi.org/10.1039/D5NR04489H
Anti-interference bimodule biosensors with Au/Cu2O hollow spheres for accurate detection of uric acid in human serum
This work presents a flexible biosensor with independent pH and uric acid modules. The integrated real-time pH calibration corrects signal drift, enabling reliable uric acid detection in human serum.
Nanoscale, 2026,18, 3095-3104
https://doi.org/10.1039/D5NR04790K
Engineering a CeO2 layer on gold nanopyramids for enhanced near-infrared photothermal conversion
Precise engineering of a CeO2 layer (3–7 nm) on anisotropic Au nanobipyramids modulated the dielectric environment, achieving 56.2% photothermal efficiency at 1064 nm, and enabling effective tumor therapy.
Nanoscale, 2026,18, 2536-2544
https://doi.org/10.1039/D5NR04209G
Element doping-driven band regulation toward stable 4.5 V sodium-ion layered oxides
Zn doping upshifts the O p-band center, strengthening TM–O bonds and stabilizing octahedral coordination. This mechanism enhances structural stability and capacity retention, providing a theoretical framework for high-voltage SLOC design.
Nanoscale, 2026,18, 1975-1985
https://doi.org/10.1039/D5NR04193G
About this collection
Nanoscale is proud to present this themed collection highlighting 2026’s rising stars of nanoscience and nanotechnology research, which gathers the very best work from researchers in the early stages of their independent career.
Each contributor was recommended by experts in their fields for carrying out work with the potential to influence future directions in nanoscience and nanotechnology. Congratulations to all the featured researchers on their important work in the field so far!