Tracking iron-associated proteomes in pathogens by a fluorescence approach
The high iron-dependence of Porphyromonas gingivalis, a major threat to oral health, inspired us to develop a fluorescence approach to mine its iron-associated proteome.
Single-cell analysis by ICP-MS/MS as a fast tool for cellular bioavailability studies of arsenite
A fast and reliable single-cell ICP-MS/MS method is presented to determine the bioavailability of metal species as well as sulfur and phosphorus as internal control after re-suspension of cells in water.
The antioxidant 2,6-di-tert-butylphenol moiety attenuates the pro-oxidant properties of the auranofin analogue
Metal-based drugs are gaining momentum as a rapidly developing area of medicinal inorganic chemistry.
The P-type ATPase inhibiting potential of polyoxotungstates
Polyoxometalates (POMs) are transition metal complexes that exhibit a broad diversity of structures and properties rendering them promising for biological purposes.
On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent
The toxic effects and accumulation mechanisms of cisplatin in healthy rat kidneys has been studied ex vivo, using the Precision Cut Tissue Slices (PCTS) method, in comparison to those exerted by an experimental cytotoxic Au(III) compound.