Themed collection New Principal Investigators: A Spotlight on Recent Appointees

6 items
Open Access Review Article

Design strategies for organelle-selective fluorescent probes: where to start?

Advancing the development of organelle-targeted small fluorescent probes by highlighting key design strategies to reveal cellular dynamics and address persistent challenges in probe design.

Graphical abstract: Design strategies for organelle-selective fluorescent probes: where to start?
From the themed collection: 2025 Reviews in RSC Advances
Open Access Paper

Computational design of Bax-inhibiting peptides

Cyclic peptides targeting Bax were designed and evaluated via MD simulations. The peptides bind Bax with high affinity, potentially modulating its apoptotic function. This approach offers a foundation for peptide-based therapeutics.

Graphical abstract: Computational design of Bax-inhibiting peptides
Open Access Paper

Fluorescent carbon dots with dual emissions and solvent-dependent properties for water detection in organic solvents

Dual emissive carbon dots for water detection in organic solvents through changes of single emissions and ratiometric signals.

Graphical abstract: Fluorescent carbon dots with dual emissions and solvent-dependent properties for water detection in organic solvents
Open Access Paper

Diffusiophoresis in porous media saturated with a mixture of electrolytes

We have developed a mathematical model that predicts diffusiophoresis in porous media saturated with a general mixture of valence symmetric and asymmetric electrolytes.

Graphical abstract: Diffusiophoresis in porous media saturated with a mixture of electrolytes
Open Access Paper

Simple divalent metal salts as robust and efficient initiators for the ring-opening polymerisation of rac-lactide

Simple salts such as Zn(OBn)2 are robust and efficient initiators for lactide polymerisation, delivering poly(lactic acid) under industrially relevant conditions.

Graphical abstract: Simple divalent metal salts as robust and efficient initiators for the ring-opening polymerisation of rac-lactide
Open Access Paper

Cystine crystal nucleation and decay in the context of cystinuria pathogenesis and treatment

We examine cystine crystal growth and decay in cystinuria. We identify the conditions which can reproduce classical hexagonal cystine crystals and highlight an unusual dissolution pattern.

Graphical abstract: Cystine crystal nucleation and decay in the context of cystinuria pathogenesis and treatment
6 items

About this collection

We are delighted to present this special collection featuring members of our community who have recently been appointed as principal investigators.

The collection is hosted across the Advances family of journals at the Royal Society of Chemistry, and features articles from authors who have started their principal investigator role within the last three years. 

Spotlight

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