Themed collection Implantable Devices

This perspective article provides an overview of the implantable medical device ecosystem, highlights recent developments, and discusses challenges and opportunities for translation of new innovative implants enabled by microtechnologies and microfabrication.

Soft based implantable devices have provided various potential diagnostic options and therapeutic methods in diverse medical fields.

A review of microfabricated implantable devices that examines the critical role of material choice in design and fabrication.

This article reviews recent developments in miniaturized neural implants for optogenetics, highlights major improvements enabled by microtechnologies, and discusses challenges faced by developers and adopters of these new technologies.

This paper presents an implantable wireless battery recharging system design for bladder pressure chronic monitoring.

Multi-functional neural probes are promising platforms to conduct efficient and effective in-depth studies of brain by recording neural signals as well as modulating the signals with various stimuli.

A new, miniaturized chemical sensor – implanted via needle biopsy – measures tissue pH and oxygen tension in vivo.

This work, focusing on an implantable drug delivery system, presents the first prototype electrolytic pump that combines a catalytic reformer and a cyclically actuated mode.

A ferromagnetic micropatterned device generating highly localized magnetic fields with controllable magnetic flux densities to manipulate neuron-like cell migration and organization at the microscale level.

We developed an artificial blood vessel implanted 3D microfluidic system for reproducing vascular functions and transvascular migration of tumor cells. Based on this model, the adhesion and transvascular migration of tumor cells across the artificial blood vessel have been well reproduced.

We demonstrate an active, implantable drug delivery device embedded with a microfluidic pump that is driven by a radio-controlled actuator for temporal drug delivery.

Bioengineering neocartilage grafts of human articular chondrocytes in a custom-built microfluidic perfusion bioreactor with integrated ultrasound standing wave trap.

A highly flexible GMR-based microfluidic analytic device was demonstrated to analyze droplets of various dimensions and different concentrations of magnetic contents.

A wearable system for intracochlear drug delivery with controllable dosing for small animals, incorporating a novel micropump and drug reservoir.

A differential dielectric sensor integrated with microfluidic chambers for implantable glucose monitoring in interstitial fluid within subcutaneous tissue.