Insight: implantable medical devices
This perspective article provides an overview of the implantable medical device ecosystem, highlights recent developments, and discusses challenges and opportunities for translation of new innovative implants enabled by microtechnologies and microfabrication.
Soft implantable microelectrodes for future medicine: prosthetics, neural signal recording and neuromodulation
Soft based implantable devices have provided various potential diagnostic options and therapeutic methods in diverse medical fields.
Materials for microfabricated implantable devices: a review
A review of microfabricated implantable devices that examines the critical role of material choice in design and fabrication.
Miniaturized optogenetic neural implants: a review
This article reviews recent developments in miniaturized neural implants for optogenetics, highlights major improvements enabled by microtechnologies, and discusses challenges faced by developers and adopters of these new technologies.
Implantable wireless battery recharging system for bladder pressure chronic monitoring
This paper presents an implantable wireless battery recharging system design for bladder pressure chronic monitoring.
Neural probes with multi-drug delivery capability
Multi-functional neural probes are promising platforms to conduct efficient and effective in-depth studies of brain by recording neural signals as well as modulating the signals with various stimuli.
Miniaturized, biopsy-implantable chemical sensor with wireless, magnetic resonance readout
A new, miniaturized chemical sensor – implanted via needle biopsy – measures tissue pH and oxygen tension in vivo.
A cyclically actuated electrolytic drug delivery device
This work, focusing on an implantable drug delivery system, presents the first prototype electrolytic pump that combines a catalytic reformer and a cyclically actuated mode.
Magnetic micro-device for manipulating PC12 cell migration and organization
A ferromagnetic micropatterned device generating highly localized magnetic fields with controllable magnetic flux densities to manipulate neuron-like cell migration and organization at the microscale level.
An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells
We developed an artificial blood vessel implanted 3D microfluidic system for reproducing vascular functions and transvascular migration of tumor cells. Based on this model, the adhesion and transvascular migration of tumor cells across the artificial blood vessel have been well reproduced.
Wireless implantable chip with integrated nitinol-based pump for radio-controlled local drug delivery
We demonstrate an active, implantable drug delivery device embedded with a microfluidic pump that is driven by a radio-controlled actuator for temporal drug delivery.
Application of an acoustofluidic perfusion bioreactor for cartilage tissue engineering
Bioengineering neocartilage grafts of human articular chondrocytes in a custom-built microfluidic perfusion bioreactor with integrated ultrasound standing wave trap.
A highly flexible and compact magnetoresistive analytic device
A highly flexible GMR-based microfluidic analytic device was demonstrated to analyze droplets of various dimensions and different concentrations of magnetic contents.
A microfluidic reciprocating intracochlear drug delivery system with reservoir and active dose control
A wearable system for intracochlear drug delivery with controllable dosing for small animals, incorporating a novel micropump and drug reservoir.
A differential dielectric affinity glucose sensor
A differential dielectric sensor integrated with microfluidic chambers for implantable glucose monitoring in interstitial fluid within subcutaneous tissue.
About this collection
This collection of papers showcases novel research in the topic of implantable devices. The collection contains review articles and primary research papers and covers topics such as implantable sensors (physical, chemical, electrochemical), actuators, systems for drug or chemical delivery, electrical connections and probes, as well as new advances in ancillary components.