Mechanochemistry: a web themed issue
Showcasing a collection of cutting edge contributions by international leaders in the field of mechanochemistry.
A review of solvent-assisted mechanochemistry covering its range of applicability, theories of mechanism, and summarizing its advantages and limitations.
Merging microfluidics and sonochemistry: towards greener and more efficient micro-sono-reactors
This article presents microfluidics technology and sonochemistry as evolving areas in tandem showing synergistic and a green future.
Mechanochemical dry conversion of
zinc oxide to zeolitic imidazolate framework
Mechanochemical dry conversion that releases water as a sole byproduct was demonstrated to provide access to morphologically-novel ZIF with a polycrystalline grain boundary and a core–shell structure.
2D and 3D photoreactive lanthanide MOFs of trans,trans-muconic acid
2D and 3D MOFs of trans,trans-muconic acid with Er3+ and Y3+ were synthesized and their photoreactivity was studied as a function of the crystal environment.
Mechanochemical synthesis of an yttrium based metal–organic framework
A metal–organic framework, MIL-78, was prepared by ball-milling YH3 with trimesic acid in the absence of solvent. The process does not generate any liquid by-products, thus validating a solid-state approach to MOF synthesis.
Facile synthesis and regeneration of Mg(BH4)2 by high energy reactive
ball milling of MgB2
We have demonstrated purely mechanochemical hydrogenation of MgB2 to Mg(BH4)2 by high energy reactive ball milling.
Size controlled mechanochemical synthesis of ZrSi2
Mechanochemical metathesis reactions were utilized to synthesize nanocrystalline ZrSi2 ranging from 9–30 nm in size.
Three-component access to
pyrroles promoted by the CAN–silver nitrate system under high-speed vibration milling conditions: a generalization of the Hantzsch pyrrole synthesis
A general version of the classical Hantzsch pyrrole synthesis under high-speed vibration milling conditions was developed.
Synthesis of borasiloxane-based
macrocycles by multicomponent condensation reactions in solution or in a ball mill
Large macrocycles containing imine and borasiloxane links are obtained by polycondensation reactions in solution or – advantageously – by mechanochemical syntheses in a ball mill.
A mechanochemically synthesised solid solution enables engineering of the sorption properties of a Werner clathrate
Mechanochemical synthesis has been used to prepare two Werner complexes and their corresponding solid solution. The solid solution exhibits sorption properties that differ from those of the pure compounds.
mechanosynthesis of aromatic amides and dipeptides from carboxylic acids and amines
Mechanochemical carbodiimide-mediated coupling reaction between commercially available carboxylic acids and amines has been employed for the environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides.
Nucleoside phosphitylation using ionic liquid stabilised phosphorodiamidites and mechanochemistry
A range of nucleoside phosphoramidites incorporating small amino substituents have been readily synthesised using ionic liquid stabilised phosphorodiamidites coupled with mechanochemistry.
Mechanosynthesis of amides in the total absence of organic solvent from reaction to product recovery
The synthesis of various amides has been realised avoiding the use of any organic solvent from activation of carboxylic acids with CDI to isolation of the amides.
Poly(ethylene glycol) as reaction medium for mild Mizoroki–Heck reaction in a ball-mill
Phosphine-free palladium-catalyzed Mizoroki–Heck reaction was performed using ball-milling in polyethylene glycol under mild conditions.
Unexpected manganese(III) acetate-mediated reactions of β-enamino carbonyl compounds with 1-(pyridin-2-yl)-enones under mechanical milling conditions
The solvent-free reactions of β-enamino carbonyl compounds with 1-(pyridin-2-yl)-enones in the presence of manganese(III) acetate unexpectedly afforded dihydrobenzofuran derivatives under mechanical milling conditions.
Effect of atmosphere on solid-state
amine– aldehyde condensations: gas-phase catalysts for solid-state transformations
The presence of water or organic solvent vapour accelerates the solid-state condensation of solid aromatic amines and aromatic aldehydes into Schiff bases.
Solvent-free chemoselective oxidation of thioethers and thiophenes by mechanical milling
Chemoselective solvent-free oxidation of organosulphur compounds to sulfones with Oxone® under mechanical milling conditions.
Interconversion between different stoichiometric forms of a three-component crystal via liquid-assisted grinding
Reversible conversion between two pamoate : DABCO : water salts with different stoichiometries is facile via liquid-assisted grinding with additional amounts of the relevant component.
grinding as a tool to aid enantiomeric resolution by cocrystallisation
Racemic malic acid is converted into two distinct diastereomeric cocrystal phases on milling with a single enantiomer of tartaric acid.
A versatile and green mechanochemical route for
aldehyde– oxime conversions
A robust, facile and solvent-free mechanochemical path for aldehyde–oxime transformations using hydroxylamine and NaOH is explored; the method is suitable for aromatic and aliphatic aldehydes decorated with a range of substituents.
Mechanosynthesis of nanocrystalline fayalite, Fe2SiO4
Nonequilibrium and nanostructured fayalite (α-Fe2SiO4) with a large volume fraction of surfaces/interfaces is synthesized via single-step mechanosynthesis.
Desymmetrisation of aromatic
diamines and synthesis of non-symmetrical thiourea derivatives by click-mechanochemistry
Symmetrical ortho- and para-phenylenediamines were cleanly desymmetrized and transformed into mono- and bis-(thio)ureas or mixed thiourea–ureas in a click-mechanochemical reaction.
piracetam and lithium salts: ionic co-crystals and co-drugs?
Mechanochemical reaction of solid piracetam with the inorganic salts LiCl and LiBr yields ionic co-crystals which are also co-drugs.
grinding for mechanochemistry: application for automated supramolecular catalysis and preparation of a metal–organic framework
An automated grinding method based on a vortex mixer enables simultaneous grinding and UV-irradiation and it is applied to solid-state cocrystallisation, photocatalysis and synthesis of MOF.
About this collection
The peer-reviewed articles in this ChemComm web themed issue will highlight recent cutting-edge achievements in the exciting field of mechanochemistry.
The guest editors of the issue are Stuart James (Queen’s University Belfast, UK) and Tomislav Friščić (McGill University, Canada).
Articles in this web themed issue will be added below as soon as possible, after they are published.