Themed collection Biomaterials for theranostics and tissue engineering, an official WBC2024 collection

12 items
Minireview

Advances in oxygenation nanozymes for overcoming diabetic ulcers

This mini-review discusses recent advances in catalase-like nanozymes for the treating diabetic ulcers. It covers the pathogenesis of diabetic ulcers with focus on hypoxia, their applications in in vivo diabetic ulcer models, and future perspectives.

Graphical abstract: Advances in oxygenation nanozymes for overcoming diabetic ulcers
Review Article

Recent advances in non-invasive in vivo tracking of cell-based cancer immunotherapies

This review highlights recent advances in non-invasive in vivo imaging tools and their applications in tracking cell-based cancer immunotherapies, providing a framework for real-time monitoring and predictive efficacy assessment.

Graphical abstract: Recent advances in non-invasive in vivo tracking of cell-based cancer immunotherapies
Open Access Paper

Chondrogenic and chondroprotective response of composite collagen I/II-hyaluronic acid scaffolds within an inflammatory osteoarthritic environment

In osteoarthritic-like environments, cartilage formation was reduced and inflammatory response was higher, and including hyaluronic acid in hydrogels modulated this response.

Graphical abstract: Chondrogenic and chondroprotective response of composite collagen I/II-hyaluronic acid scaffolds within an inflammatory osteoarthritic environment
Open Access Paper

Development of a nano-vaccine for high-grade serous ovarian cancer

An overview of the development of a vaccine for High-Grade Serous Carcinoma.

Graphical abstract: Development of a nano-vaccine for high-grade serous ovarian cancer
Open Access Paper

Multilamellar hyaluronic acid-b-poly(lactic acid) polymersomes for pathology-responsive MRI enhancement

This study introduces a biocompatible, stimuli-responsive theranostic system with ultrasmall iron oxide nanoparticles (USPIONs) encapsulated within the hyaluronic acid-b-poly(lactic acid) (HA–PLA) polymersome membrane and a model protein in the core.

Graphical abstract: Multilamellar hyaluronic acid-b-poly(lactic acid) polymersomes for pathology-responsive MRI enhancement
Open Access Paper

Enhanced in vitro transfection efficiency of mRNA-loaded polyplexes into natural killer cells through osmoregulation

The transfection efficiency of mRNA-loaded polyplexes was improved by treating NK cells with NaCl-mediated hypertonic culture media.

Graphical abstract: Enhanced in vitro transfection efficiency of mRNA-loaded polyplexes into natural killer cells through osmoregulation
Open Access Paper

Development of a VEGF-activated scaffold with enhanced angiogenic and neurogenic properties for chronic wound healing applications

Schematic showing the development of the multifaceted VEGF-activated scaffolds to promote pro-regenerative environments for chronic wound applications.

Graphical abstract: Development of a VEGF-activated scaffold with enhanced angiogenic and neurogenic properties for chronic wound healing applications
Paper

Pericardial bioscaffold coated with ECM gels and urothelial cells for the repair of a rabbit urinary bladder defect

Repair of damaged or faulty complex modular organs such as the urinary bladder is a current clinical challenge.

Graphical abstract: Pericardial bioscaffold coated with ECM gels and urothelial cells for the repair of a rabbit urinary bladder defect
Paper

Strengthening the cellular function of dermal fibroblasts and dermal papilla cells using nanovesicles extracted from stem cells using blue light-based photobiomodulation technology

Nanovesicles extracted from stem cells using blue light-based photobiomodulation enhance fibroblast ECM synthesis, angiogenesis, and WNT/β-catenin activation in hair follicle dermal papilla cells.

Graphical abstract: Strengthening the cellular function of dermal fibroblasts and dermal papilla cells using nanovesicles extracted from stem cells using blue light-based photobiomodulation technology
Paper

Optimized synthesis of biphasic calcium phosphate: enhancing bone regeneration with a tailored β-tricalcium phosphate/hydroxyapatite ratio

Biphasic calcium phosphate (BCP) is a bioceramic widely used in hard tissue engineering for bone replacement.

Graphical abstract: Optimized synthesis of biphasic calcium phosphate: enhancing bone regeneration with a tailored β-tricalcium phosphate/hydroxyapatite ratio
Paper

Acid-triggered size reduction of nanomedicines for enhancing tumor therapy efficacy

A size-reducing nanoparticle was synthesized by cross-linking β-cyclodextrin-cored multiarm polymers through a boronate ester, showing high tumor permeability and therapeutic effect.

Graphical abstract: Acid-triggered size reduction of nanomedicines for enhancing tumor therapy efficacy
Paper

Harnessing 3D printed highly porous Ti–6Al–4V scaffolds coated with graphene oxide to promote osteogenesis

Bone tissue engineering (BTE) strategies have been developed to address challenges in orthopedic and dental therapy by expediting osseointegration and new bone formation.

Graphical abstract: Harnessing 3D printed highly porous Ti–6Al–4V scaffolds coated with graphene oxide to promote osteogenesis
12 items

About this collection

Both theranostics and tissue engineering are two of the biggest areas of biomaterials with the potential to revolutionize healthcare. Theranostics conveys the idea of combining both therapy and diagnosis to provide a holistic solution for disease management. Tissue engineering has developed into an advanced and attractive option for the treatment of various diseases by combining cells, growth factors and scaffolds. To promote the development of the medical field, advances towards clinical translation are crucial. This official WBC 2024 themed collection is Guest Edited by Professor Lino Ferreira (ORCID: 0000-0001-8985-9302) (UC-Biotech, Portugal) and Professor Soo Hong Lee (ORCID: 0000-0001-6369-8301) (Dongguk University, Korea) and aims to capture the latest cutting-edge innovations presented at the meeting in both of these rapidly evolving fields including the latest fundamental and translational research.


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