Themed collection Biomaterials for theranostics and tissue engineering, an official WBC2024 collection

Advances in oxygenation nanozymes for overcoming diabetic ulcers
This mini-review discusses recent advances in catalase-like nanozymes for the treating diabetic ulcers. It covers the pathogenesis of diabetic ulcers with focus on hypoxia, their applications in in vivo diabetic ulcer models, and future perspectives.
Biomater. Sci., 2025, Advance Article
https://doi.org/10.1039/D5BM00340G
Recent advances in non-invasive in vivo tracking of cell-based cancer immunotherapies
This review highlights recent advances in non-invasive in vivo imaging tools and their applications in tracking cell-based cancer immunotherapies, providing a framework for real-time monitoring and predictive efficacy assessment.
Biomater. Sci., 2025,13, 1939-1959
https://doi.org/10.1039/D4BM01677G

Chondrogenic and chondroprotective response of composite collagen I/II-hyaluronic acid scaffolds within an inflammatory osteoarthritic environment
In osteoarthritic-like environments, cartilage formation was reduced and inflammatory response was higher, and including hyaluronic acid in hydrogels modulated this response.
Biomater. Sci., 2025, Advance Article
https://doi.org/10.1039/D5BM00033E

Development of a nano-vaccine for high-grade serous ovarian cancer
An overview of the development of a vaccine for High-Grade Serous Carcinoma.
Biomater. Sci., 2025, Advance Article
https://doi.org/10.1039/D4BM01696C

Multilamellar hyaluronic acid-b-poly(lactic acid) polymersomes for pathology-responsive MRI enhancement
This study introduces a biocompatible, stimuli-responsive theranostic system with ultrasmall iron oxide nanoparticles (USPIONs) encapsulated within the hyaluronic acid-b-poly(lactic acid) (HA–PLA) polymersome membrane and a model protein in the core.
Biomater. Sci., 2025, Advance Article
https://doi.org/10.1039/D4BM01583E

Enhanced in vitro transfection efficiency of mRNA-loaded polyplexes into natural killer cells through osmoregulation
The transfection efficiency of mRNA-loaded polyplexes was improved by treating NK cells with NaCl-mediated hypertonic culture media.
Biomater. Sci., 2025,13, 2082-2091
https://doi.org/10.1039/D4BM01661K

Development of a VEGF-activated scaffold with enhanced angiogenic and neurogenic properties for chronic wound healing applications
Schematic showing the development of the multifaceted VEGF-activated scaffolds to promote pro-regenerative environments for chronic wound applications.
Biomater. Sci., 2025,13, 1993-2011
https://doi.org/10.1039/D4BM01051E
Pericardial bioscaffold coated with ECM gels and urothelial cells for the repair of a rabbit urinary bladder defect
Repair of damaged or faulty complex modular organs such as the urinary bladder is a current clinical challenge.
Biomater. Sci., 2025,13, 1671-1682
https://doi.org/10.1039/D4BM00846D
Strengthening the cellular function of dermal fibroblasts and dermal papilla cells using nanovesicles extracted from stem cells using blue light-based photobiomodulation technology
Nanovesicles extracted from stem cells using blue light-based photobiomodulation enhance fibroblast ECM synthesis, angiogenesis, and WNT/β-catenin activation in hair follicle dermal papilla cells.
Biomater. Sci., 2025,13, 1209-1221
https://doi.org/10.1039/D4BM01591F
Optimized synthesis of biphasic calcium phosphate: enhancing bone regeneration with a tailored β-tricalcium phosphate/hydroxyapatite ratio
Biphasic calcium phosphate (BCP) is a bioceramic widely used in hard tissue engineering for bone replacement.
Biomater. Sci., 2025,13, 969-979
https://doi.org/10.1039/D4BM01179A
Acid-triggered size reduction of nanomedicines for enhancing tumor therapy efficacy
A size-reducing nanoparticle was synthesized by cross-linking β-cyclodextrin-cored multiarm polymers through a boronate ester, showing high tumor permeability and therapeutic effect.
Biomater. Sci., 2025,13, 617-626
https://doi.org/10.1039/D4BM01121J
Harnessing 3D printed highly porous Ti–6Al–4V scaffolds coated with graphene oxide to promote osteogenesis
Bone tissue engineering (BTE) strategies have been developed to address challenges in orthopedic and dental therapy by expediting osseointegration and new bone formation.
Biomater. Sci., 2024,12, 5491-5503
https://doi.org/10.1039/D4BM00970C
About this collection
Both theranostics and tissue engineering are two of the biggest areas of biomaterials with the potential to revolutionize healthcare. Theranostics conveys the idea of combining both therapy and diagnosis to provide a holistic solution for disease management. Tissue engineering has developed into an advanced and attractive option for the treatment of various diseases by combining cells, growth factors and scaffolds. To promote the development of the medical field, advances towards clinical translation are crucial. This official WBC 2024 themed collection is Guest Edited by Professor Lino Ferreira (ORCID: 0000-0001-8985-9302) (UC-Biotech, Portugal) and Professor Soo Hong Lee (ORCID: 0000-0001-6369-8301) (Dongguk University, Korea) and aims to capture the latest cutting-edge innovations presented at the meeting in both of these rapidly evolving fields including the latest fundamental and translational research.