Recent approaches for optical smartphone sensing in resource-limited settings: a brief review
Developments in the emerging fields of smartphone chemical and biosensing have dovetailed with increased interest in environmental and health monitoring for resource-limited environments, culminating in research toward field-ready smartphone sensors.
Frontiers in electrochemical sensors for neurotransmitter detection: towards measuring neurotransmitters as chemical diagnostics for brain disorders
This critical review highlights significant technical advances and in vivo studies from the last five years that facilitate the development of diagnostic tools for brain disorders.
Review: new insights into optimizing chemical and 3D surface structures of carbon electrodes for neurotransmitter detection
The carbon-fiber microelectrode has been used for decades as a neurotransmitter sensor, but many new carbon electrodes have recently been developed with beneficial electrochemical properties that take advantage of surface chemistry and surface structure.
Sampling, isolating and identifying microplastics ingested by fish and invertebrates
Microplastic debris (<5 mm) is a prolific environmental pollutant, found worldwide in marine, freshwater and terrestrial ecosystems. This review assesses the numerous different methods used to identify microplastics ingested by marine organisms.
Methodological evolutions of Raman spectroscopy in art and archaeology
During the last decades, Raman spectroscopy has grown from research laboratories to a well-established approach that is increasingly often used in archaeometry and conservation science.
Portable point-of-care diagnostic devices
This review highlights key development of point-of-care diagnostics for detecting DNA, proteins, bacteria/pathogens, and other species in samples that can be used for diagnosing disease and detecting harmful chemical and biochemical contaminants in samples. These technologies have great promise for improving the quality of life for those in the developing world.
Metrics for green analytical chemistry
Green analytical chemistry although is not a new concept, it does not have greenness metrics system. Some efforts have been made to develop suitable metrics for analytical chemistry. The present review analyses the different methods proposed for an accurate greenness metrics system.
Emerging patterns in the global distribution of dissolved organic matter fluorescence
The spectra responsible for natural dissolved organic matter fluorescence in 90 peer-reviewed studies have been compared using new similarity metrics.
Measuring elasticity of wet cellulose fibres with AFM using indentation and a linearized Hertz model
The mechanical properties of different pulp fibres in liquid were measured using an atomic force microscope.
Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5 diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosa.
Detecting carbohydrate–lectin interactions using a fluorescent probe based on DBD dyes
An efficient synthesis of a fluorescent probe is described that can be specifically bound by the mannose binding FimH protein.
Aluminium foil as a potential substrate for ATR-FTIR, transflection FTIR or Raman spectrochemical analysis of biological specimens
Aluminium foil is a potential low-cost alternative substrate for spectrochemical analyses: facilitating translation to a routine clinical or laboratory setting.
Analysis of synthetic cannabinoid agonists and their degradation products after combustion in a smoking simulator
An efficient twin-trap smoking inhalation model that simulates human inhalation has been developed; all six synthetic cannabinoids tested were detected.
19 F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids
Quantitative nuclear magnetic resonance (q-NMR) spectroscopy is a robust and reliable analytical method that possesses many advantages over conventional chromatographic techniques used in drug analysis.
SERS-based sandwich bioassay protocol of miRNA-21 using Au@Ag core–shell nanoparticles and a Ag/TiO2 nanowires substrate
Based on surface-enhanced Raman scattering (SERS) technology, Au@Ag@4MBA@5′-NH2-ssDNA probes and a Ag/TiO2@3′-NH2-ssDNA substrate were prepared and constructed into a sandwich structure to develop a high sensitivity bioassay of miRNA-21.
An integrated homogeneous SPARCL™ immunoassay for rapid biomarker detection on a chip
A very simple and rapid homogeneous SPARCL™ immunoassay with on-chip preserved dry reagents enables sensitive quantitative detection of biomarkers.
A methodology for the fast identification and monitoring of microplastics in environmental samples using random decision forest classifiers
A new yet little understood threat to our ecosystems is microplastics.
Validation of alkaline oxidation as a pre-treatment method for elemental quantification in single-walled carbon nanotubes
Certified fractions of Ni, Co and Mo in carbon nanotubes were recovered from a fused borate salt bead and measured with ICP-OES.
Chemical analysis using 3D printed glass microfluidics
Additive manufacturing (3D printing) is a disruptive technology that is changing production systems globally.
Using castor oil to separate microplastics from four different environmental matrices
An affordable, low-risk and quick method for the separation of microplastics from four environmental matrices based on castor oil.
Chiral micellar electrokinetic chromatographic separation for determination of L- and D-primary amines released from murine islets of Langerhans
A chiral micellar electrokinetic chromatography method developed to investigate D-amino acid secretions from murine islets of Langerhans.
Determination of the graphene–graphite ratio of graphene powder by Raman 2D band symmetry analysis
This paper presents a method to distinguish graphene from graphite in powdered samples by analysing the Raman 2D band symmetry.
Analytical determination of heroin, fentanyl and fentalogues using high-performance liquid chromatography with diode array and amperometric detection
We report a combination of HPLC and electrochemistry towards the detection of heroin, fentanyl and ten fentalogues.
Characterisation of thin boron-doped diamond films using Raman spectroscopy and chemometrics
A non-destructive chemometric method to determine thickness and boron concentration of as-deposited, thin, heavily doped diamond films by Raman microscopy.
Chiral analysis of β-methylamino alanine (BMAA) enantiomers after (+)-1-(9-fluorenyl)-ethyl chloroformate (FLEC) derivatization and LC-MS/MS
A developed method for chiral analysis of neurotoxin β-methylamino alanine (BMAA) allowed detection of D-BMAA in cycad seed samples.
Accurate flow in augmented networks (AFAN): an approach to generating three-dimensional biomimetic microfluidic networks with controlled flow
A network augmentation approach that adds synthetic connections to microvascular networks to induce biomimetic microfluidic flow.
Fluorescence signal-to-noise optimisation for real-time PCR using universal reporter oligonucleotides
In this study we optimised the fluorescence signal generation of contact quenched universal reporter oligonucleotides.
Measuring the relative concentration of particle populations using differential centrifugal sedimentation
The factors that affect the accuracy and precision of differential centrifugal sedimentation (DCS) for the analysis of nanoparticle concentration are described.
A novel EI-GC/MS method for the accurate quantification of anti-aging compound oleoylethanolamine in C. elegans
A novel GC-MS method for the quantification of oleoylethanolamine in C. elegans.
Regional feature extraction of various fishes based on chemical and microbial variable selection using machine learning
We introduce a method for extracting regional and habitat features of various fish species based on chemical and microbial correlations that incorporate integrated analysis and a variable selection approach.
Measuring the size and density of nanoparticles by centrifugal sedimentation and flotation
Analytical centrifugation in sedimentation and flotation modes is used to measure both the size and density of polystyrene nanoparticles.
Determination of amphetamine-type stimulants (ATSs) and synthetic cathinones in urine using solid phase micro-extraction fibre tips and gas chromatography-mass spectrometry
An optimum condition procedure applied to a SPME PDMS/DVB fiber tip in a mixture of drugs in a urine sample.
Raman spectroscopic library of medieval pigments collected with five different wavelengths for investigation of illuminated manuscripts
Stepwise identification of medieval pigments by Raman spectra data and excitation source.
A high-throughput method for orthophosphate determination of thermostable membrane-bound pyrophosphatase activity
Membrane-bound pyrophosphatases (mPPases) are homodimeric integral membrane proteins that hydrolyse pyrophosphate into orthophosphates coupled to the active transport of protons or sodium ions across membranes.
A one-step rapid screening test of Listeria monocytogenes in food samples using a real-time loop-mediated isothermal amplification turbidity assay
A rapid and specific, hly-based, loop-mediated isothermal amplification (LAMP) was applied for the detection of Listeria monocytogenes in food samples using LAMP-turbidity.
The influence of covalent immobilization conditions on antibody accessibility on nanoparticles
Antibody accessibility on the nanoparticle surface depends on the surface density rather than on the coupling conditions.
Electrochemical sensing of estradiol benzoate using hydroxyapatite with three-dimensional channel frameworks
Ubiquitous estradiol benzoate (17β-estradiol-3-benzoate) in the environment and daily life has become a hot issue in society since it has been proven to be closely associated with metastatic tumour formation.
FTIR-spectroscopic and LA-ICP-MS imaging for combined hyperspectral image analysis of tumor models
Advantages of combined image analysis were demonstrated using infrared spectroscopy and mass spectrometry while characterizing biochemical changes occurring in tumor models.
Simple method for the quantitative analysis of thin copolymer films on substrates by infrared spectroscopy using direct calibration
Automated baseline estimation followed by least squares fitting of copolymer spectrum allows quantification in terms of comonomer volume fraction.
Secondary electrospray ionization proceeds via gas-phase chemical ionization
The proton transfer reaction in secondary electrospray ionization ultimately proceeds with gas-phase ions.
A simple design atomic emission spectrometer combined with multivariate image analysis for the determination of sodium content in urine
A simple atomic flame emission platform based on multivariate image analysis is introduced for sodium quantification in urine.
Comparison of six derivatizing agents for the determination of nine synthetic cathinones using gas chromatography-mass spectrometry
Insight into mass spectrometry ions and derivatization conditions for synthetic cathinone type new psychoactive substances.
Improved assessment of accuracy and performance indicators in paper-based ELISA
Paper-based devices are an excellent match for low-cost point-of-care testing (POCT) tools.
Electrochemiluminescent detection of glyphosate using electrodes modified with self-assembled monolayers
The use of glyphosate (GlyP) in agriculture has caused environmental and health concerns in modern society. This paper presents a study of the electrochemiluminescence (ECL) behaviour of GlyP/Ru(bpy)32+ system with the aim of applying such findings to the quantification of GlyP without previous chemical derivatization.
Determination of fragrance ingredients in fish by ultrasound-assisted extraction followed by purge & trap
Acid-sensitive organic chemicals representative of fragrance materials can be isolated from fish tissue by extraction into a mild solvent followed by capture from the gas phase.
An advanced conjugation strategy for the preparation of quantum dot-antibody immunoprobes
An advanced site-specific conjugation strategy for the preparation of quantum dot-based antibody probes applicable in various immunoassays from fluorescence to electrochemical biosensors is described.
A diagnostic test for cocaine and benzoylecgonine in urine and oral fluid using portable mass spectrometry
Surface mass spectrometry methods can be difficult to use effectively with low cost, portable mass spectrometers.
An automated approach for microplastics analysis using focal plane array (FPA) FTIR microscopy and image analysis
We present an automated approach to reduce the time demand currently needed for data analyses. We have developed a novel analysis pipeline, followed by image analysis with Python and Simple ITK image processing modules.
Quantifying ingested debris in marine megafauna: a review and recommendations for standardization
Plastic pollution has become one of the largest environmental challenges we currently face, but standardized reporting is required to meet critical research needs.
Assessing the feasibility of electrophoretic separation of CaCO3 polymorphs for archaeological applications
Our proof-of-principle method offers a fundamentally different approach to non-destructive separation of archaeological materials, based on electrophoretic polymorph separation.
Highly sensitive poisoning-resistant optical carbon dioxide sensors for environmental monitoring
Resistivity of optical carbon dioxide chemosensors towards poisoning by acidic gases is significantly improved by using an additional perfluorinated polymer coating making the sensors suitable for long-term measurements.
Comparison of ion mobility-mass spectrometry and pulsed-field gradient nuclear magnetic resonance spectroscopy for the differentiation of chondroitin sulfate isomers
The unsaturated disaccharide isomers of chondroitin sulfate (CS) obtained by enzymatic digestion of the polysaccharide can be differentiated in mixtures by ion mobility MS (A) as well as pulsed-field gradient NMR (B).
Colorimetric detection of lipopolysaccharides based on a lipopolysaccharide-binding peptide and AuNPs
A facile colorimetric assay for the detection of lipopolysaccharides (LPSs) was proposed based on a LPS-binding peptide and AuNPs.
Differential quantification of SCCA1 and SCCA2 cancer antigens using a hydrogel biochip
Assay on a biochip provides a simple and accurate procedure for the differential quantitation of SCCA1 and SCCA2.
Bioparticles coated with an ionic liquid for the pre-concentration of rare earth elements from microwave-digested tea samples and the subsequent quantification by ETV-ICP-OES
An analytical procedure for straight-forward quantification of rare earth elements (REEs) in tea was developed.
The performance of single and multi-collector ICP-MS instruments for fast and reliable 34S/32S isotope ratio measurements
The performance and validation characteristics of different single collector inductively coupled plasma mass spectrometers based on different technical principles (ICP-SFMS, ICP-QMS in reaction and collision modes, and ICP-MS/MS) were evaluated in comparison to the performance of MC ICP-MS for fast and reliable S isotope ratio measurements.
Improved strategies for selection and characterization of new monoclonal anti-carbamazepine antibodies during the screening process using feces and fluorescence polarization immunoassay
Methodological suggestions for the production of monoclonal hapten antibodies.
A fluoride-selective electrode (Fse) for the quantification of fluoride in lithium-ion battery (Lib) electrolytes
In this work, a fluoride-selective electrode (FSE) was applied with regard to the analysis of fluoride in lithium hexafluorophosphate-based lithium-ion battery (LIB) electrolytes.
Measurement uncertainty associated with shipboard sample collection and filtration for the determination of the concentration of iron in seawater
ANOVA used to determine uncertainty associated with the way in which deep, open ocean seawater samples were collected and conditioned (filtered).
Fingerprinting of falsified artemisinin combination therapies via direct analysis in real time coupled to a compact single quadrupole mass spectrometer
Using portable single-quadrupole DART-MS technology, suspect pharmaceuticals can be rapidly and efficiently analyzed providing detailed information on their true origin.
Sensing chlorinated hydrocarbons via miniaturized GaAs/AlGaAs thin-film waveguide flow cells coupled to quantum cascade lasers
Mid-infrared (MIR) sensors based on attenuated total reflection (ATR) spectroscopy provide robust, rapid and sensitive platforms for the detection of low levels of organic molecules and pollutants.
Rapid detection of toxic compounds in tobacco smoke condensates using high-resolution 1H-nuclear magnetic resonance spectroscopy
In 2012, the FDA Tobacco Products Scientific Advisory Committee published a list of 93 harmful and potentially harmful constituents (HPHCs) of tobacco products and tobacco smoke.
UV-VIS spectroscopy for monitoring yogurt stability during storage time
Color, texture and taste are key elements of a consumer's buying decision; thus, monitoring the stability of these features throughout the entire period of yogurt validity is fundamental for dairy product producers.
In situ monitoring of additives during CO2 gas hydrate formation
The combination of pressure/temperature traces with in situ mid-infrared fiberoptic evanescent field spectroscopy as advanced sensing concept for CO2 gas hydrate analysis.
Rapid, high-throughput, and quantitative determination of orange juice adulteration by Fourier-transform infrared spectroscopy
Orange juice is a hugely popular, widely consumed, and high price commodity typically traded in a concentrate form making it highly susceptible to adulteration.
Multi-scale magnetic nanoparticle based optomagnetic bioassay for sensitive DNA and bacteria detection
An optomagnetic bioassay is optimized by means of extending the linear range in the presence of larger nanoparticles.
Geographical differentiation of a monovarietal olive oil using various chemical parameters and mid-infrared spectroscopy
Olive oil discrimination with different analytical techniques.
AFM force indentation analysis on leukemia cells
To complement the existing literature, an automated batch analysis protocol was developed to perform unbiased data processes on AFM indentation data measured over leukemia cancer cells.
Rapid detection and identification of bacterial meningitis pathogens in ex vivo clinical samples by SERS method and principal component analysis
Three pathogens, N. meningitidis, H. influenzae, and S. pneumoniae, have been successfully detected and identified in clinical cerebrospinal fluids using SERS method.
The soybean lipoxygenase-fluorescein reaction may be used to assess antioxidant capacity of phytochemicals and serum
The new LOX-FL method highlights improvement of serum antioxidant capacity after antioxidant intake better than widely used methods.
About this collection
This collection features recent open access articles published in Analytical Methods.