Themed collection Surface-enhanced Raman scattering
Surface-enhanced Raman scattering
Welcome to this Analyst themed issue on surface-enhanced Raman scattering, guest edited by Duncan Graham, Richard van Duyne and Bin Ren.
THE DISCOVERY OF SERS: an idiosyncratic account from a vibrational spectroscopist
Patrick Hendra looks back at the people and experiments that led to the discovery of SERS.
Highly sensitive and reproducible silicon-based surface-enhanced Raman scattering sensors for real applications
During the past few decades, thanks to silicon nanomaterials’ outstanding properties, different dimensional silicon nanostructures have been employed for designing and fabricating high-performance surface-enhanced Raman scattering (SERS) sensors for chemical and biological detection.
Recent topics on single-molecule fluctuation analysis using blinking in surface-enhanced resonance Raman scattering: clarification by the electromagnetic mechanism
Fluctuating single sp2 carbon clusters at single hotspots of silver nanoparticle dimers investigated by surface-enhanced Raman scattering (SERS), indicating that SERS has become an ultrasensitive tool for clarifying molecular functions on plasmonic metal nanoparticles (NPs).
Nanoparticles and intracellular applications of surface-enhanced Raman spectroscopy
Surface-enhanced Raman spectroscopy offers ultra-sensitive vibrational fingerprinting within biological cells.
Surface-enhanced resonance Raman scattering of hemoproteins and those in complicated biological systems
The SERRS spectra of heme are influenced by structural changes, orientation, and selective adsorption on the Ag surface.
Recognition of tumor cells by immuno-SERS-markers in a microfluidic chip at continuous flow
SERS active nanoparticles were labeled with a reporter molecule and conjugated with anti-EpCAM antibodies.
Temporal drift in Raman signal intensity during SERS measurements performed on analytes in liquid solutions
SERS experiments performed with the substrate immersed in liquid solutions are subjected to a temporal drift in the Raman signal intensity. This effect could have a negative impact on in situ quantitative chemical analysis.
Measuring the effects of fractionated radiation therapy in a 3D prostate cancer model system using SERS nanosensors
Using Surface Enhanced Raman Spectroscopy to measure cell death caused by radiation in a 3D model of prostate cancer.
A tunable Au core–Ag shell nanoparticle tip for tip-enhanced spectroscopy
A single Au nanoparticle (NP) with a diameter of 5 nm was transferred to the end of a Si-tip through a picking process, and an Ag shell with a controlled thickness was formed on the Au core.
Sensitive SERS nanotags for use with 1550 nm (retina-safe) laser excitation
1550 nm SERS nanotags have been developed to provide effective SERS with picomolar detection limits when excited with a retina-safe laser.
Investigation of the chemical origin and evidential value of differences in the SERS spectra of blue gel inks
Highly swellable polymer films doped with Ag nanoparticle aggregates (poly-SERS films) have been used to record very high signal : noise ratio, reproducible surface-enhanced resonance Raman (SERRS) spectra of in situ dried ink lines and their constituent dyes using both 633 and 785 nm excitation.
Rapid, accurate, and comparative differentiation of clinically and industrially relevant microorganisms via multiple vibrational spectroscopic fingerprinting
Comparison of the applicability and accuracy of FT-IR, Raman and SERS, as physicochemical whole organism fingerprinting approaches, for differentiation of a range of microbial samples.
High throughput LSPR and SERS analysis of aminoglycoside antibiotics
Aminoglycoside antibiotics are used in the treatment of infections caused by Gram-negative bacteria, and are often dispensed only in severe cases due to their adverse side effects.
Reliable SERS detection of nitrite based on pH and laser irradiance-dependent diazotization through a convenient sampling micro-chamber
A SERS-enabled micro-chamber was constructed for reliable and pretreatment-free detection of NO2− based on a pH and laser irradiance-dependent diazotization.
Assembling substrate-less plasmonic metacrystals at the oil/water interface for multiplex ultratrace analyte detection
Designing substrate-less plasmonic metacrystals for the multiplex ultratrace detection of analytes from both organic and aqueous phases.
In solution SERS sensing using mesoporous silica-coated gold nanorods
Mesoporous silica-coated gold nanorods (AuNR@MS) act as a colloidally stable Raman sensing platform with a built-in analyte size cutoff.
Unforeseen distance-dependent SERS spectroelectrochemistry from surface-tethered Nile Blue: the role of molecular orientation
The tether length of Nile Blue impacts molecular orientation leading to unique SERS spectroelectrochemistry.
Ultrasensitive detection of thyrotropin-releasing hormone based on azo coupling and surface-enhanced resonance Raman spectroscopy
A SERRS-based assay for thyrotropin-releasing hormone quantification coupled with the azo reaction was proposed with simplicity, rapidness, selectivity and ultrahigh sensitivity.
Biomolecular environment, quantification, and intracellular interaction of multifunctional magnetic SERS nanoprobes
Multifunctional composite nanoprobes, Ag–Magnetite and Au–Magnetite, were manipulated in fibroblast cells and characterized using SERS, LA-ICP-MS, and nanotomography.
SERS speciation of the electrochemical oxidation–reduction of riboflavin
The electrochemical oxidation and reduction of riboflavin is detected and characterized by SERS.
SERS detection of uranyl using functionalized gold nanostars promoted by nanoparticle shape and size
Quantitative uranyl detection using surface-enhanced Raman scattering and functionalized gold nanostars.
iSERS microscopy guided by wide field immunofluorescence: analysis of HER2 expression on normal and breast cancer FFPE tissue sections
Surface-enhanced Raman scattering (SERS) microscopy is an emerging imaging technique for tissue-based cancer diagnostics.
Silver colloids as plasmonic substrates for direct label-free surface-enhanced Raman scattering analysis of DNA
Unraveling the role played by the surface chemistry of silver colloids in the direct SERS analysis of DNA.
Time-dependent SERS spectra monitoring the dynamic adsorption behavior of bipyridine isomerides combined with bianalyte method
Based on the bianalyte method, time-dependent surface-enhanced Raman spectrosopy (SERS) spectra were applied to observe and study the competitive adsorption of bipyridine isomerides 2,2′-bpy and 4,4′-bpy.
Highly stable SERS pH nanoprobes produced by co-solvent controlled AuNP aggregation
Production of gold nanoparticle (AuNP) surface-enhanced Raman spectroscopy (SERS) nanoprobes requires replicable aggregation to produce multimers with high signal intensity.
About this collection
Surface-enhanced Raman scattering (SERS) has become a mature vibrational spectroscopic technique in the chemical, material, and life sciences. This themed issue, Guest Edited by Professors Duncan Graham, Bin Ren and Richard Van Duyne, highlights the recent discoveries and advances in the field of SERS.