An efficient artificial light-harvesting system with two-step sequential energy transfer has been successfully constructed based on supramolecular self-assembly.
Three new iridium(III) polypyridyl complexes were synthesized. The cytotoxic activity in vitro and in vivo, apoptosis, cell cycle arrest, mitochondrial membrane potential, ROS and the expression of Bcl-2 family proteins were investigated.
The endoplasmic reticulum stress (ERS)-induced autophagy and apoptosis are favorable for the suppression of many cancer types.
Gastrointestinal tumors are the most frequently diagnosed malignancy and the second highest contributor to cancer mortality.
Gastric cancer (GC) is a great threat to human health and life.