In this work, we systematically screened and imaged multitype gallbladder cancer both in vitro and in vivo using carboxyl/amino functionalized polymer dots as a dual-modal NIR/photoacoutic probe for the first time.
An effective strategy was constructed for the small-scale preparation of AIE-active Pdots, which displayed reversibly distinct dual-color fluorescence in cancer cells.
The aggregation of amyloid-β (Aβ) peptides is closely related to Alzheimer's disease (AD). These functionalized Pdots manifest effective photo-triggered suppression ability for the Aβ aggregation and cytotoxicity under irradiation.
Pdot/g-C3N4 heterojunctions exhibit an HER of 929.3 μmol h−1 g−1 and AQE of 5.7% at 420 nm without a metallic catalyst.
Conjugated polymer dots with tunable absorptions by controlling the structure have been engineered for multiscale photoacoustic imaging-guided photothermal therapy.