We demonstrate that positively-charged NBD amines can effectively scavenge biological H2S in live cells and in mice.
The piperazine ring is a very important factor in governing molecular structure to generate the special properties of a compound.
A semipinacol rearrangement of vinylogous α-ketol cocatalyzed by a cinchona-based primary amine and Brønsted acids can be achieved with good enantiocontrol, and theoretical investigations have been performed to uncover and understand it in detail.
We report on aromatic N-glucosides that inhibit selectively the cancer metabolism via two coexistent mechanisms: by deprivation of the glucose uptake through blocking of GLUT1 and by formation of sequestering nanonet through biocatalytic self-assembly.
A mitochondria-targeted red-emitting probe is designed and prepared for H2S detection in living cells and zebrafish.