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The chemistry and biology of guanidine secondary metabolites


Roberto G. S. Berlinck, Darlon I. Bernardi, Taicia Fill, Alessandra A. G. Fernandes and Igor D. Jurberg
Nat. Prod. Rep., 2021, Advance Article

Abstract

Guanidine metabolites isolated from microorganisms, marine invertebrates, terrestrial animals and plants are reviewed, as well as the biosynthesis, total synthesis, biological activities and ecological roles of guanidine natural products.


Heterologous expression and biochemical characterisation of cyanotoxin biosynthesis pathways


Alescia Cullen, Leanne A. Pearson, Rabia Mazmouz, Tianzhe Liu, Angela H. Soeriyadi, Sarah E. Ongley and Brett A. Neilan
Nat. Prod. Rep., 2019,36, 1117-1136

Abstract

This review discusses cyanotoxin biosynthetic pathways and highlights the heterologous expression and biochemical studies used to characterise them.


A rapid and ultrasensitive colorimetric biosensor based on aptamer functionalized Au nanoparticles for detection of saxitoxin


Le Qiang, Yu Zhang, Xin Guo, Yakun Gao, Yingkuan Han, Jun Sun and Lin Han
RSC Adv., 2020,10, 15293-15298

Abstract

We demonstrate a facile and ultrasensitive colorimetric sensor based on gold nanoparticles (Au NPs) and aptamer (Au NPs-aptamer biosensor) for specific and quantitative detection of STX.


Rapid and sensitive detection of nodularin-R in water by a label-free BLI aptasensor


Shengqun Ouyang, Bo Hu, Rong Zhou, Dejing Liu, Dingfa Peng, Zhengang Li, Zhen Li, Binghua Jiao and Lianghua Wang
Analyst, 2018,143, 4316-4322
From themed collection: Analyst Recent HOT articles

Abstract

A novel label-free BLI aptasensor was developed for the rapid and sensitive detection of nodularin-R in water.


Selection and application of aptamers with high-affinity and high-specificity against dinophysistoxin-1


Zhen Li, Bo Hu, Rong Zhou, Xiaojuan Zhang, Ruizhe Wang, Yun Gao, Mingjuan Sun, Binghua Jiao and Lianghua Wang
RSC Adv., 2020,10, 8181-8189

Abstract

For the first time, the aptamer of dinophysistoxin-1 was successfully obtained with high affinity and specificity by SELEX, and an aptasensor with a detection range from 40 to 600 nM was developed by biolayer interferometry.


CHAPTER 5
Targeting Marine Toxins and Other Adulterants in Fish


Caroline Murphy
Rapid Antibody-based Technologies in Food Analysis, 2019, 75-111

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