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A hollow-nanosphere-based microfluidic biosensor for biomonitoring of cardiac troponin I


Nawab Singh, Prabhakar Rai, Md. Azahar Ali, Rudra Kumar, Ashutosh Sharma, B. D. Malhotra and Renu John
J. Mater. Chem. B, 2019,7, 3826-3839

Abstract

Cardiovascular diseases (CVDs) are the leading causes of death worldwide.


A paper microfluidics-based fluorescent lateral flow immunoassay for point-of-care diagnostics of non-communicable diseases


Satheesh Natarajan, Fengmei Su, Joseph Jayaraj, Malay I. Iesh Shah and Youju Huang
Analyst, 2019,144, 6291-6303

Abstract

An easy-to-use, low-cost and portable fluorescent lateral flow immunoassay based on paper microfluidics was developed for the point-of-care diagnosis of non-communicable diseases.


Reduced graphene oxide-gold nanoparticles-catalase-based dual signal amplification strategy in a spatial-resolved ratiometric electrochemiluminescence immunoassay


Jun-Tao Cao, Xiao-Long Fu, Fu-Rao Liu, Shu-Wei Ren and Yan-Ming Liu
Analyst, 2020,145, 91-96

Abstract

A novel spatial-resolved electrochemiluminescent (ECL) ratiometry for cardiac troponin I (cTnI) analysis was developed using resonance energy transfer (RET) and a coreactant consumption strategy for signal amplification.


A one-step potentiometric immunoassay for plasma cardiac troponin I using an antibody-functionalized bis-MPA–COOH dendrimer as a competitor with improved sensitivity


Erru Ni, Yizhen Fang, Fangfang Ma, Gaoshun Ge, Jingyi Wu, Yingying Wang, Yao Lin and Huabin Xie
Anal. Methods, 2020, Advance Article

Abstract

Herein, we have reported a new one-step potentiometric immunoassay for the sensitive and specific detection of human plasma cardiac troponin I (cTnI), a biomarker of cardio-cerebrovascular diseases.


Rapid and sensitive detection of cardiac troponin I using a force enhanced immunoassay with nanoporous membrane


Won-Suk Chang, Peng Li, Sandeep Kakade, Ying Xiong, Hao Shang, Yong Zhang and Gil U. Lee
Nanoscale, 2020, Advance Article

Abstract

Schematic of the loading of superparamagnetic beads (red spheres) into a nanoporous membrane (orange membrane) in a lab on a chip device with window (on top) for the rapid and ultrasensitive detection of cardiac troponin I.


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