Combining imaging and anticancer properties with new heterobimetallic Pt(II)/M(I) (M = Re, 99mTc) complexes


Letícia Quental, Paula Raposinho, Filipa Mendes, Isabel Santos, Carmen Navarro-Ranninger, Amparo Alvarez-Valdes, Huaiyi Huang, Hui Chao, Riccardo Rubbiani, Gilles Gasser, Adoración G. Quiroga and António Paulo
Dalton Trans., 2017,46, 14523-14536
From themed collection: Frontiers in Radionuclide Imaging and Therapy

Abstract

New metal-based anticancer agents with imaging, chemotherapeutic and photosensitizing properties.


In vitro/in vivo “peeling” of multilayered aminocarboxylate gold nanoparticles evidenced by a kinetically stable 99mTc-label


Francisco Silva, Lurdes Gano, Maria Paula Cabral Campello, Rosa Marques, Isabel Prudêncio, Ajit Zambre, Anandhi Upendran, António Paulo and Raghuraman Kannan
Dalton Trans., 2017,46, 14572-14583
From themed collection: Frontiers in Radionuclide Imaging and Therapy

Abstract

The BBN-Au-DTDTPA coating is selectively released upon interaction with glutathione (GSH), rendering this nanoplatform potentially useful for GSH-mediated drug delivery.


Mangiferin functionalized radioactive gold nanoparticles (MGF-198AuNPs) in prostate tumor therapy: green nanotechnology for production, in vivo tumor retention and evaluation of therapeutic efficacy


A. Y. Al-Yasiri, M. Khoobchandani, C. S. Cutler, L. Watkinson, T. Carmack, C. J. Smith, M. Kuchuk, S. K. Loyalka, A. B. Lugão and K. V. Katti
Dalton Trans., 2017,46, 14561-14571
From themed collection: Frontiers in Radionuclide Imaging and Therapy

Abstract

We report here production of MGF-198AuNPs and its application for prostate tumor therapy.


Technetium-99m complexes of L-arginine derivatives for targeting amino acid transporters


Maurício Morais, Vera F. C. Ferreira, Flávio Figueira, Filipa Mendes, Paula Raposinho, Isabel Santos, Bruno L. Oliveira and João D. G. Correia
Dalton Trans., 2017,46, 14537-14547
From themed collection: Frontiers in Radionuclide Imaging and Therapy

Abstract

The metal complex Tc2 exhibits relevant internalization in several cancer cell lines, likely to be mediated by cationic amino acid transporters.


Fluoroquinolones as imaging agents for bacterial infection


Syed Ali Raza Naqvi and Karl Drlica
Dalton Trans., 2017,46, 14452-14460
From themed collection: 2017 Frontier and Perspective articles

Abstract

Three ways to radioactively label fluoroquinolones are available, thereby creating multiple options for developing a diagnostic for deep-seated bacterial infection.


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Identification of metabolites of liquiritin in rats by UHPLC-Q-TOF-MS/MS: metabolic profiling and pathway comparison in vitro and in vivo


Xia Zhang, Caijuan Liang, Jintuo Yin, Yupeng Sun and Lantong Zhang
RSC Adv., 2018,8, 11813-11827
From themed collection: Editors' collection: Food Engineering, Science, Technology, and Nutrition

Abstract

Liquiritin (LQ), the main bioactive constituent of licorice, is a common flavoring and sweetening agent in food products and has a wide range of pharmacological properties, including antidepressant-like, neuroprotective and anti-cancer properties.


Synthesis, structures, redox properties, and theoretical calculations of thiohalide capped octahedral hexanuclear technetium(III) clusters


Takashi Yoshimura, Kojiro Nagata, Ayumi Matsuda, Toshiki Omote, Yasushi Kino, Tsutomu Takayama, Tsutomu Sekine and Atsushi Shinohara
Dalton Trans., 2019,48, 14085-14095

Abstract

Thiohalide capped octahedral hexanuclear technetium(III) clusters were synthesized and characterized.


Synthesis of Os(II)–Re(I)–Ru(II) hetero-trinuclear complexes and their photophysical properties and photocatalytic abilities


Yasuomi Yamazaki and Osamu Ishitani
Chem. Sci., 2018,9, 1031-1041
From themed collection: In celebration of Kazunari Domen’s 65th birthday, 2018

Abstract

Novel Os(II)–Re(I)–Ru(II) hetero-trinuclear complexes, which can absorb a wide range of visible light and induce durable CO2 reduction, were synthesised.


Synthesis of a porphyrin with histidine-like chelate: an efficient path towards molecular PDT/SPECT theranostics


Steven Y. Yap, Huguette Savoie, Isaline Renard, Benjamin P. Burke, Harry C. Sample, Saul Michue-Seijas, Stephen J. Archibald, Ross W. Boyle and Graeme J. Stasiuk
Chem. Commun., 2020,56, 11090-11093

Abstract

“Click” chemistry was utilised to synthesis multifunctional theranostic drugs with therapeutic, diagnostic, and prostate-cancer targeting capabilities, paving a path towards “personalised” medicine ultimately improving patients' quality of life.


Photocatalytic CO2 reduction using metal complexes in various ionic liquids


Yoshiyuki Asai, Haruka Katsuragi, Kazuki Kita, Taro Tsubomura and Yasuomi Yamazaki
Dalton Trans., 2020,49, 4277-4292

Abstract

Photoreduction of CO2 catalysed by metal complexes successfully took place in various ionic liquids with relatively high durability.


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