Singlet carbenes as mimics for transition metals: synthesis of an air stable organic mixed valence compound [M2(C2)+˙; M = cyclic(alkyl)(amino)carbene]


Liqun Jin, Mohand Melaimi, Liu Liu and Guy Bertrand
Org. Chem. Front., 2014,1, 351-354
From themed collection: Celebrating the 2016 RSC Prize and Award Winners

Abstract

A bis-carbene-stabilized ethynyl radical cation, a purely organic mixed valence compound, is indefinitely air stable.


Reductive decyanation of malononitriles and cyanoacetates using photoactivated neutral organic super-electron-donors


Eswararao Doni and John A. Murphy
Org. Chem. Front., 2014,1, 1072-1076
From themed collection: Celebrating the 2016 RSC Prize and Award Winners

Abstract

A metal-free reductive procedure for decyanation of malononitriles and cyanoacetates, using photoactivated organic electron donors, is described.


Copper-catalyzed three-component synthesis of 5-acetamidoimidazoles from carbodiimides, acyl chlorides and isocyanides


Giulia Sapuppo, Qian Wang, Dominique Swinnen and Jieping Zhu
Org. Chem. Front., 2014,1, 240-246
From themed collection: Celebrating the 2016 RSC Prize and Award Winners

Abstract

Three-component reaction of carbodiimides, acyl chlorides, and isocyanides took place smoothly at room temperature to afford 1,4-disubstituted 5-acetamidoimidazoles in good yields.


Accurate and precise quantification of Cu,Zn-SOD in human red blood cells using species-specific double and triple IDMS


Julia Gleitzmann, Andrea Raab, Dirk Schulze, Hermann Wätzig, Jörg Feldmann and Claudia Swart
J. Anal. At. Spectrom., 2016,31, 1922-1928
From themed collection: Speciation Analysis

Abstract

Species-specific double and triple isotope dilution mass spectrometry (IDMS) was applied for the precise quantification of Cu,Zn-SOD in human erythrocytes.


Structure and bonding of group 4-nickel heterobimetallics supported by 2-(diphenylphosphino)pyrrolide ligands


Peter L. Dunn, Rebecca K. Carlson, Laura Gagliardi and Ian A. Tonks
Dalton Trans., 2016,45, 9892-9901
From themed collection: New Talent: Americas

Abstract

The synthesis of a full series of group 4/nickel complexes supported by a 2-(diphenylphosphino)pyrrolide (NP) ligand is reported.


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Peptide supramolecular materials for therapeutics


Kohei Sato, Mark P. Hendricks, Liam C. Palmer and Samuel I. Stupp
Chem. Soc. Rev., 2018,47, 7539-7551
From themed collection: Supramolecular Medicine

Abstract

Supramolecular assembly of peptide-based monomers into nanostructures offers many promising applications in advanced therapies. In this Tutorial Review, we introduce molecular designs to control the structure and potential biological function of supramolecular assemblies.


Synthesis and peptide functionalization of hyperbranched poly(arylene oxindole) towards versatile biomaterials


Al Halifa Soultan, Thomas Verheyen, Mario Smet, Wim M. De Borggraeve and Jennifer Patterson
Polym. Chem., 2018,9, 2775-2784

Abstract

An azide derivative of hyperbranched poly(arylene oxindole) is synthesized for postgrafting by CuAAC. RGDS functionalization promotes cell attachment and proliferation.


Designing well-defined photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells


Elisa M. Ovadia, David W. Colby and April M. Kloxin
Biomater. Sci., 2018,6, 1358-1370
From themed collection: Biomaterials Science Lectureship Winners

Abstract

In this work, we establish an approach for the three-dimensional (3D) culture and differentiation of induced pluripotent stem cells (iPSCs) within well-defined synthetic matrices using light-based chemistries of relevance for the study of both disease and regeneration.


3D printing with peptide–polymer conjugates for single-step fabrication of spatially functionalized scaffolds


Paula Camacho, Hafiz Busari, Kelly B. Seims, Peter Schwarzenberg, Hannah L. Dailey and Lesley W. Chow
Biomater. Sci., 2019,7, 4237-4247

Abstract

Solvent-cast 3D printing with peptide–polymer conjugates introduces a versatile platform to spatially organize peptides to guide local cell behavior.


Hierarchical supramolecular hydrogels: self-assembly by peptides and photo-controlled release via host–guest interaction


Chih-Wei Chu and Bart Jan Ravoo
Chem. Commun., 2017,53, 12450-12453

Abstract

Using photoresponsive host–guest chemistry, three different payloads can be photo-released successively from the same peptide hydrogel.


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