From the journal RSC Chemical Biology Peer review history

17-Jul-2023

Dear Dr Hodgkinson:

Manuscript ID: CB-REV-06-2023-000105
TITLE: PROTAC Chemical Probes for Histone Deacetylase Enzymes

Thank you for your submission to RSC Chemical Biology, published by the Royal Society of Chemistry. I sent your manuscript to reviewers and I have now received their reports which are copied below.

After careful evaluation of your manuscript and the reviewers’ reports, I will be pleased to accept your manuscript for publication after revisions.

Please revise your manuscript to fully address the reviewers’ comments. When you submit your revised manuscript please include a point by point response to the reviewers’ comments and highlight the changes you have made. Full details of the files you need to submit are listed at the end of this email.

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I look forward to receiving your revised manuscript.

Yours sincerely,
Cai-Guang Yang, Ph.D.
Associate Editor/RSC Chemical Biology
Professor/Shanghai Institute of Materia Medica, CAS
Phone: +86-021-50806029
Email: yangcg@simm.ac.cn

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Reviewer 1

This manuscript provides an excellent overview of the state of the art in the field of HDAC degraders.
My only recommendation is to include the very recent paper from the Nomura laboratory: ACS Cent. Sci. 2023, 9, 5, 915–926

I fully support publication of the review article in RSC Chem. Biol.

Reviewer 2

Very wonderful manuscript which is accepted without any comments.

Thank you to the reviewers for the kind comments on the manuscript and for full endorsement for publication in RSC chemical biology. Responses to referees are below:

Referee: 1

Comments to the Author
This manuscript provides an excellent overview of the state of the art in the field of HDAC degraders.
My only recommendation is to include the very recent paper from the Nomura laboratory: ACS Cent. Sci. 2023, 9, 5, 915–926

The citation for this paper and a brief discussion on this paper have been included in the section on 'PROTACs as chemical probes' when the topic of molecular glues is mentioned. This seems the most appropriate place.

I fully support publication of the review article in RSC Chem. Biol.

Referee: 2

Comments to the Author
Very wonderful manuscript which is accepted without any comments.

Thank you.

27-Jul-2023

Dear Dr Hodgkinson:

Manuscript ID: CB-REV-06-2023-000105.R1
TITLE: PROTAC Chemical Probes for Histone Deacetylase Enzymes

Thank you for submitting your revised manuscript to RSC Chemical Biology. I am pleased to accept your manuscript for publication in its current form.

You will shortly receive a separate email from us requesting you to submit a licence to publish for your article, so that we can proceed with the preparation and publication of your manuscript.

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With best wishes,

Cai-Guang Yang, Ph.D.
Associate Editor/RSC Chemical Biology
Professor/Shanghai Institute of Materia Medica, CAS
Phone: +86-021-50806029
Email: yangcg@simm.ac.cn

If you need to contact the journal, please use the email address chembio@rsc.org

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