Advances in Biological Solid-State NMR: Proteins and Membrane-Active Peptides Editors: Frances Separovic, Akira Naito
Structural Studies of Small Bioactive Compounds Interacting with Membranes and Proteins
Lipopolysaccharide Induces Raft Domain Expansion in a Cholesterol-Containing Membrane
Deuterium NMR of Mixed Lipid Membranes
NMR of Lipids and Lipid/Peptide Mixtures
Dynamic Structure Analysis of Peptides in Membranes by Solid-State NMR
Helical Membrane Protein Structure: Strategy for Success
A Promising Prognosis for Solid-State NMR of Functional Membrane Protein Complexes
2H Solid-State NMR Study of Peptide–Membrane Interactions in Intact Bacteria
NMR Studies of Small Molecules Interacting with Amyloidogenic Proteins
Solid-State NMR Studies of β -Amyloid Fibrils and Related Assemblies
Subject Index
Publication details
- Print publication date
- 06 Mar 2014
- Copyright year
- 2014
- Print ISBN
- 978-1-84973-910-8
- PDF eISBN
- 978-1-78262-744-9
- ePub eISBN
- 978-1-78262-119-5
About this book
The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation.
Advances in Biological NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis.
Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid state NMR. A thorough and comprehensive discussion of this promising technique follows, which is essential reading for those working or studying at postgraduate level in this exciting field.