How the polarity of carbohydrates can be used in chemistry
Sugar-based hydrotropes: preparation, properties and applications
Exo -glycals as useful tools for anomeric functionalization of sugars
Electrochemical glycosylation
Enzymatic thioglycosylation: current knowledge and challenges
Sucrose as chiral platform in the synthesis of macrocyclic receptors
Polyester functionalized carbohydrates via organocatalyzed ring-opening polymerization
Liquid crystal glycolipids
Sugar decorated receptors for chiral anions
Publication details
About this book
Volume 40 of Carbohydrate Chemistry: Chemical and Biological Approaches demonstrates the importance of the glycosciences for innovation and societal progress. Carbohydrates are molecules with essential roles in biology and also serve as renewable resources for the generation of new chemicals and materials. Honouring Professor André Lubineau’s memory, this volume resembles a special collection of contributions in the fields of green and low-carbon chemistry, innovative synthetic methodology and design of carbohydrate architectures for medicinal and biological chemistry.
Green methodology is illustrated by accounts on the industrial development of water-promoted reactions (C-glycosylation, cycloadditions) and the design of green processes and synthons towards sugar-based surfactants and materials. The especially challenging transformations at the anomeric center are presented in several contributions on glycosylation methodologies using iron or gold catalysis, electrochemical or enzymatic (thio)glycosylation, exo-glycal chemistry and bioengineering of carbohydrate synthases. Then, synthesis and structure of multivalent and supramolecular oligosaccharide architectures are discussed and related to their physical properties and application potential, e.g. for deepening our understanding of biological processes, such as enzymatic pathways or bacterial adhesion, and design of antibacterial, antifungal and innovative anticancer vaccines or drugs.