Contemporary Approaches to Kinase Lead Generation
The Learning and Evolution of Medicinal Chemistry against Kinase Targets
Non-Protein Kinases as Therapeutic Targets
The Drug Discovery and Development of Kinase Inhibitors Outside of Oncology
Allosteric Activators of Glucokinase (GK) for the Treatment of Type 2 Diabetes
Subject Index
Publication details
https://doi.org/10.1039/9781849733557About this book
Kinase inhibition remains an area of significant interest across academia and in the pharmaceutical industry. There are now many marketed drugs which target kinases and a significant number of compounds are currently in various stages of clinical development. Although there have been a number of publications on kinase inhibition, this is the first to examine the future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and focuses on a number of key areas for kinase inhibition over the coming years.
Author information
Richard A Ward and Frederick W Goldberg have both been working at AstraZeneca in Alderley Park for over 5 years. Richard Ward is a Computational Chemist and Frederick Goldberg is a Medicinal Chemist. They have worked on a significant number of kinase projects and are named on various kinase-related papers and patents and have both presented externally on the subject.