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DNA Damage, DNA Repair and Disease: Volume 1 Editors: Miral Dizdaroglu, R Stephen Lloyd


Publication details


Print publication date
18 Nov 2020
Copyright year
2021
Print ISBN
978-1-78801-889-0
PDF eISBN
978-1-83916-076-9
ePub eISBN
978-1-83916-086-8

About this book

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

From the book series:
Chemical Biology