Phenotypic Drug Discovery Editors: Beverley Isherwood, Angelique Augustin
Preliminary content
Front Matter
Pages 1 - 6
Preface
Pages 7 - 8
Contents
Pages 21 - 26
Chapter 5
Contemporary Techniques for Target Deconvolution and Mode of Action Elucidation
Markus Schirle and Jeremy L. Jenkins
Pages 83 - 103
Chapter 6
Artificial Intelligence as an Enabler for Phenotypic Drug Discovery
Nicole Renaud and Yuan Wang
Pages 104 - 117
Subject Index
Pages 242 - 245
Publication details
- Print publication date
- 10 Dec 2020
- Copyright year
- 2021
- Print ISBN
- 978-1-78801-876-0
- PDF eISBN
- 978-1-83916-072-1
- ePub eISBN
- 978-1-83916-079-0
About this book
Phenotypic drug discovery has been highlighted in the past decade as an important strategy in the discovery of new medical entities. How many marketed drugs are derived from phenotypic screens? From the most recent examples, what were the factors enabling target identification and validation? This book answers these questions by elaborating on fundamental capabilities required for phenotypic drug discovery and using case studies to illustrate approaches and key success factors. Written and edited by experienced practitioners from both industry and academia, this publication will equip researchers with a thought-provoking guide to the application and future development of contemporary phenotypic drug discovery for clinical success.