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Cucurbiturils and Related Macrocycles Editor: Kimoon Kim


About this book

Cucurbiturils (CBs) are a young family of molecular containers, able to form stable complexes with various guests, including drug molecules, amino acids and peptides, saccharides, dyes, hydrocarbons, perfluorinated hydrocarbons, and proteins. Since the discovery of the first CB, the field has seen tremendous growth with respect to the synthesis of new homologues and derivatives, the discovery of record binding affinities of guest molecules in their hydrophobic cavity, and associated applications ranging from sensing to drug delivery.

Cucurbiturils and Related Macrocycles

provides a complete overview of CB chemistry, covering the fundamental aspects including its history, synthesis, host–guest chemistry and the thermodynamic basis thereof. The book will tackle specialist topics such as redox chemistry of CB complexes and CBs in the gas phase, and will address the recent trends of the application of CBs in other fields including biology and materials. Edited by a pioneer of cucurbituril chemistry, and with contributions from global experts, this title will appeal to students and researchers working in supramolecular chemistry, materials chemistry, nanotechnology, organic chemistry, biochemistry and chemical biology.


Book content

  • Introduction: History and Development
  • Synthesis Aspects
  • Host-guest Chemistry of the CB[n] family
  • CB Properties and the Thermodynamic Basis of Host-guest Binding
  • CBs as Reaction Vessels
  • CB-based Sensors
  • Cucurbituril Complexes of Redox Active Guests
  • CB-based Molecular Machines and Switches
  • CB-coordination Chemistry
  • Gas Phase CB chemistry
  • CBs on Surfaces
  • Functionalization and Self-assembly of Nanoparticles through CB[n]-based binding motifs
  • CB-based Polymeric Materials
  • Molecular Recognition of Biomolecules by CB[n]
  • Drug Delivery
  • Supramolecular Latch
  • Cucurbit[n]uril-type receptors: Influence of building block exchange, deletion and augmentation
  • Hemicucurbiturils and Related Macrocycles

The print version of this book is planned for release on 13 November 2019. Information about this book is subject to change without notice.

Pre-order hardback £179.00 *
* Exclusive of taxes
This book contains 550 pages.

Publication details

Copyright year: 2020
Print ISBN: 978-1-78801-500-4
ePub eISBN: 978-1-78801-917-0