Recent Perspectives in Catalysis under Continuous Flow
Green Biotransformations under Flow Conditions
Perspectives on the Use of Flow Systems to Carry Out Organic Photochemical Reactions
Sustainable Approaches to C–H Functionalizations Through Flow Techniques
Ionic Polymerisation and New Approaches to Polymerisation under Flow Conditions
New Microreactor Designs for Practical Applications Realized by Additive Manufacturing
Additively Manufactured Advanced Flow Reactors for Enhanced Heat and Mass Transfer
Integrated Microreaction Systems of Microdevices with Conventional Equipment
Automation of Flow Chemistry
Upscaling the Aza-Diels–Alder Reaction for Pharmaceutical Industrial Needs in Flow Chemistry
Industrial Continuous-flow Chemistry under cGMP Conditions
About this book
Historically pharmaceutical and fine chemical products have been synthesised using batch methods, but increasingly chemists are looking towards flow chemistry as a greener and more efficient alternative. In flow chemistry reactions are performed in a reactor with the reactants pumped through it. It has the benefit of being easily scaled up and it is straightforward to integrate synthesis, workup and analysis into one system. Flow chemistry is considered a greener alternative to batch chemistry because it is easier to control and minimise hazardous intermediates and by-products. There is significant interest in the use of flow chemistry both in the lab and on an industrial scale.
Flow Chemistry provides an update on recent advances that have been made in the field. Particular emphasis is given to the new integrated approaches that bring together several elements to implement flow processes as a regular green chemistry tool for the chemical industries. With chapter contributions from several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries.
Santiago V Luis is Professor of organic chemistry at the University Jaume I, Castellon, Spain.
He studied Chemistry at the University of Zaragoza and completed his PhD at the University of Valencia in 1983 working on mechanistic studies using functional polymers. After postdoctoral work at the University of Pittsburgh (USA) under the supervision of J. Rebek, in Supramolecular chemistry, he obtained an academic appointment at the University Jaume I in Castellón (Spain) where he is Head of the research group in Supramolecular and Sustainable Chemistry. Research areas involve Supramolecular and Biomimetic chemistry and new tools in Sustainable and Green Chemistry, with emphasis in catalysis and flow chemistry using polymer-supported reagents and catalysts.
Eduardo Garcia-Verdugo is Professor of organic chemistry at the University Jaume I, Castellon, Spain.
He obtained his chemistry degree at the University of Valencia (1995) and his PhD in chemistry at the University Jaume I (Spain) in 2001. After working as a researcher at Nottingham University (UK) under the supervision of M. Poliakoff (until 2004) as a MSCA fellow, he returned to Spain and worked as a Ramon y Cajal fellow at the University Jaume I until 2009, and then he obtained a permanent position as Cientifico Titular of CSIC at ICP (Madrid) (2009–2010). In 2010, he moved to a permanent academic position at the University Jaume I. Currently, he is working on the integration of different so-called enabling techniques (catalysis, polymeric materials, continuous flow processes, microreactors, bio-catalysis, neoteric solvents (ILs, SCFs)) to develop more efficient and greener organic transformations.