Nanoparticle–Protein Corona Complex: Composition, Kinetics, Physico–Chemical Characterization, and Impact on Biomedical Applications
NP–Protein Corona Interaction: Characterization Methods and Analysis
An Analytical Approach to Investigate Nanoparticle–Protein Corona Complexes
Impact of Nanoparticle–Protein Interactions on Biological Assays
Computer Simulations for Understanding Nanoparticle-biomolecule Corona Formation
In Silico Approaches to Design and Characterize Peptide-based Nanostructures
Nanomaterial–Blood Interactions: A Biomedical Perspective
The Protein Corona: Applications and Challenges
About this book
Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration.
This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.