About this book
Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration.
This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.
Book content
- Biological Significance to the Nanoparticles Protein Corona
- Methodologies Used for Characterisation of NP Protein Corona
- Impact of Nanoparticles Protein Interactions on Ecotoxicity Studies
- Computational Approaches in Understanding the Effect of Nanoparticles Protein Corona to Cellular Membranes
- In-silico Approaches to Design and Characterize the Peptide-based Nanostructures
- Effect of Nanoparticle Protein Corona in Genotoxicity Assessment
- Introduction to the Nanoparticles Protein Corona
- Protein Corona: Applications and Challenges
- Factors Affecting the Nanoparticles Protein Corona Formation
- Nanomaterials–Vascular Components Interactions Including Nanoparticle–Plasma Protein Biointerface
- Impact of Nanoparticles Protein Interactions on Biological Assays
- Methods to Detect the Nanoparticles Protein Corona
The print version of this book is planned for release on 30 July 2019. Information about this book is subject to change without notice.
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