Capillary Electrophoresis–Mass Spectrometry for Metabolomics – From Metabolite Analysis to Metabolic Profiling
CE-MS Workflows for Metabolomics: A Focus on Sample Preparation
Capillary Electrophoresis–Mass Spectrometry Using Non-covalently Coated Capillaries for Metabolic Profiling of Biological Samples
Capillary Electrophoresis–Mass Spectrometry for Metabolomics Using New Interfacing Designs
Stacking or On-line Sample Concentration in CE-MS for Metabolomics
On-line Solid-phase Extraction Capillary Electrophoresis–Mass Spectrometry and Data Analysis Approaches for Metabolomics
CE-MS for Anionic and Cationic Metabolic Profiling: System Optimization and Applications
CE-MS for Metabolomics: A Comparison with Other Techniques
Potential of CE-MS for Chiral Metabolic Profiling
Single-cell Metabolomics with Capillary Electrophoresis–Mass Spectrometry
Capillary Electrophoresis–Mass Spectrometry for Lipid Analysis
Multisegment Injection–Capillary Electrophoresis–Mass Spectrometry: A Robust Platform for High Throughput Metabolite Profiling with Quality Assurance
About this book
Capillary electrophoresis–mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In this book, the unique features of CE-MS for metabolomics studies are highlighted including CE separation modes, capillary coatings and practical aspects of CE-MS coupling alongside a comprehensive overview of recent technological developments and applications.
CE-MS can be considered a relatively new technique in the field of metabolomics and it is therefore important to inform the scientific community about the possibilities of advanced CE-MS approaches for metabolomics studies. This book outlines the potential of this technique for researchers working in metabolomics, bioanalytics and biomarker analysis.
Strongly believing in the power of analytical technology to contribute to a better understanding of biochemical mechanisms underlying diseases, Rawi Ramautar studied both Pharmacochemistry and Analytical Sciences at Vrije Universiteit of Amsterdam in order to have the right background for a PhD training in this direction. In 2010, he completed his PhD on the development of capillary electrophoresis-mass spectrometry methods for metabolomics at the Utrecht University. Intrigued by metabolomics for disease prediction and diagnosis, Rawi switched to the Leiden University Medical Center to broaden his horizon on this topic. In 2013 and 2017, Rawi Ramautar received the highly prestigious Veni and Vidi personal grants, respectively, from the Netherlands Organisation for Scientific Research. Currently, he is a Principal Investigator (tenured) at the Leiden Academic Center for Drug Research of the Leiden University where his group is developing microscale analytical workflows for volume-restricted biomedical problems.