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Exploiting Natural Diversity for Industrial Enzymatic Applications
Artificial Metalloenzymes
Computational Techniques for Efficient Biocatalysis
Modulating Enzyme Activity via Incorporation of Non-canonical Amino Acids
Enhancing Enzymatic Performance via Restricted Sequence Space Approaches
Customizing Transcription-factor Biosensors for Modern Biotechnology
Engineering Enzymes for Natural Product Biosynthesis and Diversification
Impact of Synthetic Biology on Secondary Metabolite Biosynthesis
Self-contained Biocatalysts
Designing Multi-enzymatic Systems for the Preparation of Optically Active Molecules
Artificial Biocatalytic Cascades to Alcohols and Amines
Subject Index
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About this book
The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.