Transient Ischemic Attack, Traumatic Brain Injury, and Ischemic Stroke: Risk Factors and Treatments
Inflammatory Changes in Cerebral Ischemic Injury: Cellular and Molecular Involvement
Biomarkers of Acute Brain Injury and Surrogate Endpoints in Traumatic Brain Injury and Stroke Translational Studies
Difficulties of Translating Outcomes from Animal Studies to Clinical Trials
Neuroprotective Therapies for Ischemic Stroke
The Molecular Neuroprotective Strategies in Cerebral Ischemia: An Insight into Emerging Treatments for Oxidative Stress
Identification of MicroRNAs as Targets for Treatment of Ischemic Stroke
Combined Drug–Diagnostic Test Co-development for Predicting and Preventing Brain Impairments
Advances in Diagnostics and Treatment of Neurotoxicity after Sports-related Injuries
Functional Predictors for Prognosis and Recovery after Mild Traumatic Brain Injury
Predictors for Prognosis and Recovery from Unconsciousness Due to Brain Trauma
Neurotoxicity in Spinal Cord Impairments
Advanced Approaches in Stem Cell Therapy for Stroke and Traumatic Brain Injury
Testing and Mechanisms of Neuroprotective Agents for Cerebral Ischemic Injury in Clinical Trials, 2010–2016
Difficulties in Clinical Trials to Treat Traumatic Brain Injury and Stroke
Challenges in Using Biomarkers in Central Nervous System Applications
Resolving Difficult Case Scenarios by Incorporating Stroke Biomarkers in Clinical Decision-making
Development of Novel Test Platforms for the Assessment of Brain Injury
Advancements and Challenges in Hyperacute Stroke Translational Research
About this book
A rise in the number of young and old patients suffering from a stroke or traumatic brain injury has led to the need for better drug development and treatment, as well as diagnosis and prevention of ischemic stroke and traumatic brain injury. This book provides a comprehensive overview of scientific advancements in these areas.
Chapters provide the latest knowledge in neuroscience, biotechnology, and personalized medicine applicable to acute brain injuries. Development of neuroprotective drugs is treated in detail. Chemical biomarkers for detection, imaging and preventative strategies are covered to provide medicinal chemists with a broad view of translational aspects of the field.
This book will be useful to postgraduate students and researchers in medicinal chemistry and pharmacology as well as specialists in the acute brain injury field.