Inflammatory Changes in Cerebral Ischemic Injury: Cellular and Molecular Involvement
Difficulties of Translating Outcomes from Animal Studies to Clinical Trials
Neuroprotective Therapies for Ischemic Stroke
Identification of MicroRNAs as Targets for Treatment of Ischemic Stroke
Combined Drug–Diagnostic Test Co-development for Predicting and Preventing Brain Impairments
Functional Predictors for Prognosis and Recovery after Mild Traumatic Brain Injury
Neurotoxicity in Spinal Cord Impairments
Advanced Approaches in Stem Cell Therapy for Stroke and Traumatic Brain Injury
Difficulties in Clinical Trials to Treat Traumatic Brain Injury and Stroke
Challenges in Using Biomarkers in Central Nervous System Applications
Development of Novel Test Platforms for the Assessment of Brain Injury
Subject Index
Publication details
About this book
A rise in the number of young and old patients suffering from a stroke or traumatic brain injury has led to the need for better drug development and treatment, as well as diagnosis and prevention of ischemic stroke and traumatic brain injury. This book provides a comprehensive overview of scientific advancements in these areas.
Chapters provide the latest knowledge in neuroscience, biotechnology, and personalized medicine applicable to acute brain injuries. Development of neuroprotective drugs is treated in detail. Chemical biomarkers for detection, imaging and preventative strategies are covered to provide medicinal chemists with a broad view of translational aspects of the field.
This book will be useful to postgraduate students and researchers in medicinal chemistry and pharmacology as well as specialists in the acute brain injury field.