Nanomedicines

Nanomedicines and nanopharmacology is a rapidly developing and evolving field with new techniques and applications under constant development. This book will provide an overview of the chemistry of nanocarrier design and the considerations that need to be made when developing a nanomedicine. Providing an understanding of the relationship of nanocarrier, drug and targetting moieties and physico-chemical properties, this title will provide an accurate and current representation of the field by addressing the promises, prospects and pitfalls of nanomedicine. Covering a wide range of areas in detail, this book will provide an excellent companion for medicinal chemists, pharmacologists and biochemists working in industry or academia.

From the book series:
Drug Discovery

Nanomedicines: Design, Delivery and Detection Editor: Martin Braddock

Front Matter

Preface

Contents

Design Considerations for Properties of Nanocarriers on Disposition and Efficiency of Drug and Gene Delivery

Targeting Cyclins and Cyclin-dependent Kinases Involved in Cell Cycle Regulation by RNAi as a Potential Cancer Therapy

Nanoparticle Carriers to Overcome Biological Barriers to siRNA Delivery

Magnetic Targeting as a Vehicle for the Delivery of Nanomedicines

The Development of Theranostics – Imaging Considerations and Targeted Drug Delivery

The Role of Imaging in Nanomedicine Development and Clinical Translation

Anticancer Agent-Incorporating Polymeric Micelles: from Bench to Bedside

Polymeric Nanoparticles and Cancer: Lessons Learnt from CRLX101

Nanodelivery Strategies in Breast Cancer Chemotherapy

Developing a Predictable Regulatory Path for Nanomedicines by Accurate and Objective Particle Measurement

Nanomedicine: Promises and Challenges

The Challenge of Regulating Nanomedicine: Key Issues

Doxil^® – the First FDA-approved Nano-drug: from Basics via CMC, Cell Culture and Animal Studies to Clinical Use

Subject Index

Publication details

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